bioRxiv Neuroscience

Novel, small molecules targeting the 5-HT4R receptor protect against stress-induced maladapative behavior with efficacy across age https://www.biorxiv.org/content/10.1101/2025.10.08.680712v1

Neural Underpinnings of Olfactory Dysfunction across Parkinson's and Alzheimer's Spectra https://www.biorxiv.org/content/10.1101/2025.10.07.681050v1

Biophysical simulations of fMRI responses using realistic microvascular models: insights into distinct hemodynamics in humans and mice https://www.biorxiv.org/content/10.1101/2025.10.08.680976v1

Human AUTS2 regulates neurodevelopmental pathways via dual DNA/RNA binding. https://www.biorxiv.org/content/10.1101/2025.10.07.681056v1

EEG Microstates Reveal Differential Network Dynamics under Constant Current and Oscillatory Brain Stimulation https://www.biorxiv.org/content/10.1101/2025.10.08.681119v1

Closed-loop beta stimulation enhances beta activity and motor behaviour https://www.biorxiv.org/content/10.1101/2025.10.07.680961v1

Novelty-dependent enhancement of sustained attention and electrophysiological signatures via transcutaneous auricular vagus nerve stimulation. https://www.biorxiv.org/content/10.1101/2025.10.07.680948v1

Sleep Facilitates Pattern Separation through SK Channel-Mediated Sparse Coding https://www.biorxiv.org/content/10.1101/2025.10.08.681112v1

Across-speaker articulatory reconstruction from sensorimotor cortex for generalizable brain-computer interfaces https://www.biorxiv.org/content/10.1101/2025.10.08.680888v1

PTH-Induced Behavioral and Metabolic Alterations in Mouse Models of Hyperparathyroidism https://www.biorxiv.org/content/10.1101/2025.10.07.681037v1

Profiles of Neuroaffective Responding to Natural Reward-Predicting Cues and Alcohol Images in Alcohol Use Disorder: An Event-Related Potential Approach https://www.biorxiv.org/content/10.1101/2025.10.07.680946v1

Convergent and Divergent Cerebellar Alterations in 22q11.2 Copy Number Variants https://www.biorxiv.org/content/10.1101/2025.10.07.679846v1

Prenatal Acetaminophen Exposure Does Not Disrupt Human Fetal Brain Development in Cortical Organoid Models https://www.biorxiv.org/content/10.1101/2025.10.07.681041v1

Exploring the likelihood of the membrane pollution hypothesis with a physiologically plausible biophysical model. https://www.biorxiv.org/content/10.1101/2025.10.06.680798v1

Myelin pathology is a key feature of X-linked Dystonia Parkinsonism https://www.biorxiv.org/content/10.1101/2025.10.07.680990v1

Unmasking Early Microglial Remodeling in an Alzheimer's Disease Mouse Model https://www.biorxiv.org/content/10.1101/2025.10.07.681006v1

Parallelized Brightfield and Fluorescence Imaging of Organoids Using a Scalable Multi-Camera Platform https://www.biorxiv.org/content/10.1101/2025.10.07.681020v1

ASSESSMENT OF CELL-TYPE-SPECIFIC EXCITATORY SYNAPTIC STRENGTH IN THE DORSOLATERAL STRIATUM OF GOAL-DIRECTED AND HABITUAL COCAINE-SEEKING BEHAVIOR https://www.biorxiv.org/content/10.1101/2025.10.07.680788v1

Behavioral evidence for visually dominant audiovisual motion integration https://www.biorxiv.org/content/10.1101/2025.10.07.680959v1

Neural Computational Model Predicts Attentional Dynamics during Immersive Search in Virtual Reality https://www.biorxiv.org/content/10.1101/2025.10.07.680957v1

iGABASnFR Imaging Reveals Diffusion-Driven GABA Clearance in the Cerebral Cortex https://www.biorxiv.org/content/10.1101/2025.10.07.680664v1

Aggregation-prone alpha-synuclein proteoforms and dysregulated molecular signatures in the vermiform appendix of synucleinopathy patients https://www.biorxiv.org/content/10.1101/2025.10.07.680938v1

Sildenafil-driven cone PDE6 inhibition alters receptive-field properties of retinal ganglion cells ex vivo https://www.biorxiv.org/content/10.1101/2025.10.07.680926v1

Disinhibition of a recurrent attractor gates a persistent goal signal for navigation https://www.biorxiv.org/content/10.1101/2025.10.07.681003v1

Arousal increases locus coeruleus blood flow, salience-related brain responses, and modulates negative-valence attentional biases https://www.biorxiv.org/content/10.1101/2025.10.07.680973v1

Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1

Mechanical Properties of the Developing Brain in a Model of Fetal Alcohol Spectrum Disorders and Relationships to Perineuronal Net Integrity https://www.biorxiv.org/content/10.1101/2025.10.07.680991v1

Controlled Delivery of a Neurotrophic Factor in the Adult Mouse Brain Using Engineered Microglia https://www.biorxiv.org/content/10.1101/2025.10.06.680702v1

Glial cell-intrinsic and non-cell autonomous toxicity in a Drosophila C9orf72 neurodegeneration model https://www.biorxiv.org/content/10.1101/2025.10.07.680869v1

Mu suppression reveals auditory-motor predictions after short motor training in non-musicians https://www.biorxiv.org/content/10.1101/2025.10.06.680771v1