Antonia Weberling

Very excited to present my research focussing on the evolutionary differences of epiblast morphogenesis across amniotes next week at the kick-off of @vgzt2021.bsky.social season 7!
A story of 🐁,🧍,🐓 & many 🦎🦎🦎🦎

Very excited to be presenting my research at the kick-off of the @vgzt2021.bsky.social season 7!

This collaborative project was conducted across the following institutes. @stowersinstitute.bsky.social @mdanderson.bsk.social @oxfordwomenshealth.bsky.social @cambiochem.bsky.social @ox.ac.uk @cam.ac.uk

Thank you coauthors @shylonatasha.bsky.social @zgrif26.bsky.social @thomsanger.bsky.social @hollfelderlab.bsky.social @swilliamslabox.bsky.social @aussiebiologist.bsky.social @rrbehringer.bsky.social

Through confocal imaging we describe basement membrane deposition in the ovary during folliculogenesis. We can report a double basement membrane deposited on either side of the granulosa cell layer surrounding the follicles.

Exploring the sub-cellular architecture of the germinal bed & stage II follicles, we could analyse the granulosa (g) and theca (th) cell layers surrounding stage II follicles. Primordial follicles (pf) start exhibiting enlarged nuclei and cytoplasm!

Oogenesis takes place in 10 stages. It starts in the oogonial nest - a mitotic stem cell niche within the germinal bed - which then undergo meiosis to form primordial follicles
We identified oogonia and primordial follicles using section H&E staining paired with confocal DAPI/WGA staining!

Thrilled that our preprint on anole oocyte formation is now online @holyanole.bsky.social !
Such a great collaboration merging our expertise in anole reproductive tract morphology and early embryogenesis to understand how egg cells form!

ecoevojobs.net 2025-26

UPDATE: The 2025-2026 list of faculty and postdoc positions in ecology and evolutionary biology is out! Be sure to check out this active and helpful community run resources! docs.google.com/spreadsheets...

Congratulations @juliaeckert.bsky.social! Such a great pipeline that will help many researchers doing analysis of 3D epithelial tissues!

6/6
Massive Thanks to co-first @shylonatasha.bsky.social & all coauthors @hollfelderlab.bsky.social @swilliamslabox.bsky.social‬ @aussiebiologist.bsky.social
for our collaboration between
@stowersinstitute.bsky.social @oxford_uni ‪@cam.ac.uk‬ @oxfordwomenshealth.bsky.social‬ @cambiochem.bsky.social

5/6
Lumenogenesis coincides with circular expression of gastrulation marker Brachyury prior to AP-axis formation suggesting a novel role of Brachyury preceding #gastrulation

4/6
We suggest alternative anterior-posterior #patterning regulation in chameleons with anterior marker genes Cerberus expressed in the middle (arrows) and on the posterior (asterisks) of the embryo but not on the anterior side, while Lefty is completely absent.
#AP-axis

3/6
A purse string mechanism through supra-cellular actin cables closes the epiblast lumen dorsally suggesting a novel form of epiblast lumenogenesis and amniotic cavity formation.

2/6
The #squamate chameleon diverges from what has been reported for #chicken pre-gastrulation morphogenesis
Starting off as flat plate the chameleon hollows and adopts a dome-like shape. Hinge points at the side of the dome result in the formation of amniotic folds.
#devbio #evodevo

1/6
Preprint Alert
Ever thought that humans & chameleons look alike?
We follow chameleon development from fertilisation to oviposition & uncover the process through which they form an epiblast lumen that exhibits striking similarity to human embryos
#devbio #evodevo

www.biorxiv.org/content/10.1...

Honouring our friend Dr. Svetlana Jovanic who passed away after battling cancer for almost 3 years.

a passionate researcher
a keen photographer
a generous and loyal friend.

She investigated #zebrafish & #gastruloids using #lightsheet #microscopy.

We will not forget her.

🧬🇬🇧 UK Evo-Devo Starter Pack go.bsky.app/SgRdF9T

Had a lovely time presenting my new chameleon study at the UK #EvoDevo meeting on Friday!
Great discussions and really interesting talks!

If there is still space, could I please be added?
I'm working on comparative analysis of embryogenesis across the amniote phylum using non-model organisms.

Congratulations to Svetlana and all coauthors, this is such a cool study!

The preprint of my dear friend Svetlana Jovanic showing that
"cell behaviour during gastrulation is robust to the deficiency of yolk topology & signalling originating from the yolk syncytial layer."
is now online!
Super interesting read! #zebrafish #embroids #DevBio

www.biorxiv.org/content/10.1...

Congratulations @aaronhgriffing.bsky.social & team!

such cool data!

really impressive imaging and 3D reconstructions!

I'm over the moon to announce that my first novel "Leopold - the Boy at the Lake" will be published later this year at Wichern Verlag in Germany.

Just got the cover in - now, it starts to feel real...

Freue mich wahnsinnig, dass mein #Erstling dieses Jahr im Wichern Verlag erscheinen wird!

Thanks so much!

Congratulations! A really nice study!

Amazing! Thank you so much!

Hello Angelo,
may I ask whether you could add me to the starter pack? I'm setting up my independent research in evodevo - comparing early embryogenesis in amniotes. we have just published our first study in that direction focussing on early development of the brown anole - more soon to follow...

Thank you to all collaborators for such an amazing project
@aussiebiologist.bsky.social
@shylonatasha.bsky.social
@thomsanger.bsky.social
@holyanole.bsky.social
@hollfelderlab.bsky.social
Marta Marchini, Katherine Starr, Melainia McClain, & Hannah Wilson

Looking forward to our next projects!

Pre‐oviposition development of the brown anole (Anolis sagrei) Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipul.....

1/2
Very excited to announce the publication of our study on early anole embryogenesis @devdynamics.bsky.social

Read the full article here!

anatomypubs.onlinelibrary.wiley.com/doi/full/10....

@stowersinstitute.bsky.social
@ox.ac.uk
@oxfordwomenshealth.bsky.social
@loyolachicago.bsky.social