Ania Holubecki

Poster from D. C. Perez entitled "increased inter-individual variability in functional network organization of older adults compared to younger adults"

3) @dianacperez.bsky.social is presenting TUESDAY AM at LPB028

Diana used precision datasets of younger and older adults to individual brain network maps
▶️ she shows that variability increases across the lifespan, suggesting new models for the development of individual differences

Image of Z. Ladwig poster entitled "Precision fMRI reveals densely interdigitated network patches with conserved motifs in the individual lateral prefrontal cortex"

1) @zachladwig.bsky.social will be available on SATURDAY PM at poster CC14

He’ll show his work using precision fMRI to identify new common network motifs in the PFC and investigate how network borders support executive function.
Preprint: www.biorxiv.org/content/10.1...

I'm recruiting PhD students for my lab at Northwestern! I'm reviewing applications for the Department of Psychology for the Cognitive Affective Neuroscience and Clinical areas, due 12/1. 🧠

Come join the CATS Lab: nucatslab.com

Learn about our latest research: iamh.northwestern.edu/research/res...

Congrats @josephsalvo.bsky.social! 🧠🎓

Happy to have helped collect this dataset.

Our new paper is out now in Neuron! 🎉 With @vaibhavtripathi.bsky.social @maxwellelliott.bsky.social Joanna Ladopoulou, Wendy Sun, Mark Eldaief, and Randy Buckner

Paper link: www.sciencedirect.com/science/arti...

End of August means ECVP! This year, I am here (in beautiful Mainz) with a special mission - to find postdocs who will join us in (equally beautiful) Krakow, PL! Drop me a DM if you are interested!
@ecvp.bsky.social

Are there good neuro/neuroimaging journals that still accept brief communications, i.e., short papers focused on 1-2 results? Interesting results but not "major impact".
#neuroskyence

High frequency broadband activity detected noninvasively in infants distinguishes wake from sleep states https://www.biorxiv.org/content/10.1101/2025.08.08.668962v1

Overall, we found that noninvasive HFB detection is not only possible at sites where the skull hasn’t fully developed, but sufficiently robust to enable systematic investigation of early cognitive development!

Thanks to my co-authors, as well as to the Dynamic Brain Lab for their support! 🙂

Plot of how the reliability of the wake > sleep effect at the single-baby level relates to the number of trials used in analyses. Shading represents the standard error of the mean.

At the single-baby level, the same wake > sleep effects were detected with 60% reliability using as few as 50 seconds of data per state. Although this reliability is lower than the 90% group-level reliability, 60% is higher than reliabilities seen in other developmental scalp EEG studies.

Subject-by-trial reliability plots for midline (Fz, Cz, Pz), frontal (F3, F4), central (C3, C4), and occipital (O1, O2) channels. Darker red colors represent greater reliability (>50%), and darker grayscale colors represent lower reliability (<50%). White on the right portions of plots represents missing data resulting from channel exclusion within individual babies due to low data quality.

We found that when varying both the number of trials and babies included in group analyses, the reliability of the wake > sleep effect stabilized at ~90% at around 25 seconds of data per state, with as few as 10 babies (see panels A and C) and even fewer babies for occipital channels (see panel D)!

Topographic plots comparing HFB power between 25 seconds of wake data versus 25 seconds of sleep data per baby, across 18 babies. More red regions represent greater HFB power during wake states, and darker grayscale regions represent greater HFB power during sleep states. Significant channels are marked with larger black dots. There are 10 topographic plots because analyses were done 10 times for reliability analyses.

At the group level, we found that HFB power was greater in wake versus sleep states in midline and central channels near fontanelles, as well as occipital channels over thin skull. This was replicated 9/10 times (90% reliability) using as little as 25 seconds of data per state!

We analyzed scalp EEG data from 18 babies during wake and sleep states (5-second trials). Past intracranial work has shown that HFB is greater in wake vs. sleep states, so to see whether we could detect this signal in babies, we compared HFB power between these two states. 😴👶

Schematic of estimated fontanelle and suture locations (in pink), overlaid with scalp EEG channels arranged according to the international 10-20 system.

iEEG electrode implantation is extremely rare in babies because they have fontanelles (see pink regions in image) and thin skull. However, scalp EEG channels over these regions may be able to detect HFB since they are closer to brain tissue, allowing for less signal drop off!

HFB indexes local brain activity and is predominantly studied invasively using iEEG. This signal is tricky to detect with scalp EEG because it is attenuated as it passes through skull.

HFB has been studied across development, but to our knowledge, not in babies - why not?

High frequency broadband activity detected noninvasively in infants distinguishes wake from sleep states High frequency broadband activity (HFB; 70-150 Hz) indexes local brain activity. It is predominantly studied using invasive measures due to signal drop off from skull attenuation. We hypothesized that...

I’m very excited to share my FIRST first-author preprint - the result of my Northwestern graduate school lab rotation with Lisa Johnson!

We detected HFB in babies (1-4 months) noninvasively using scalp EEG, distinguishing wake from sleep states. 👶

Link: doi.org/10.1101/2025...

I still get chills

Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts

Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE

see videos, read paper, follow thread
doi.org/10.31234/osf...

Congrats @josephsalvo.bsky.social and @rementurus.bsky.social !

SO exciting to see the first results from this project, which we started when the lab first opened! Collecting this dataset was my main focus during my RCship, and we’re very grateful to the epilepsy patients who gave much of their time to make this happen. Congratulations, Chris! 🧠

Technical Associate I, Kanwisher Lab MIT - Technical Associate I, Kanwisher Lab - Cambridge MA 02139

I’m hiring a full-time lab tech for two years starting May/June. Strong coding skills required, ML a plus. Our research on the human brain uses fMRI, ANNs, intracranial recording, and behavior. A great stepping stone to grad school. Apply here:
careers.peopleclick.com/careerscp/cl...
......

Congratulations Nate! BYU is lucky to have you. :)

The Saxe Lab @ MIT is hiring! We seek one lab manager to start in summer 2025. Research in our lab focuses on social cognition (learn more on saxelab.mit.edu).

Please apply at: tinyurl.com/saxe2025 (Job ID 31993).

Review of applications starts on March 24, 2025.

Sharing appreciated. Thank you!

“Imagine publishing a preprint” :) Congrats @rementurus.bsky.social!

QR code and stand up for science logo, with paypal donation link: https://www.paypal.com/ncp/payment/9ZTLJN7MH6Z7E

📣 Want to DONATE to help us Stand Up for Science on March 7th? *NEW LINK!*

Make a tax-deductible donation using the QR code below!

Direct link: www.paypal.com/ncp/payment/...

#scienceforall #sciencenotsilence #standupforscience2025

Within-Individual Precision Mapping of Brain Networks Exclusively Using Task Data Precision mapping of brain networks within individuals has become a widely used tool that prevailingly relies on functional connectivity analysis of resting-state data. Here we explored whether networ...

[PREPRINT❗️❗️] Very excited to share our latest work on precision mapping of brain networks exclusively using task data!🧠
With @maxwellelliott.bsky.social Joanna Ladopoulou, Mark Eldaief, and Randy Buckner
www.biorxiv.org/content/10.1...
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Chicago, IL Location: Federal Plaza 211 S Clark St, Chicago, IL, United States Address: 211 S Clark St, Chicago, IL 60604 Time: 12-3 PM

Hey #Chicago!
It's time to take a stand for #science. We are rallying on March 7 at noon at the Federal Plaza. Start making your signs!

Info
standupforscience2025.org/chicago-il/

RSVP (optional)
www.eventbrite.com/e/stand-up-f...

#standupforscience #scienceforall
@standupforscience.bsky.social

Chicago, IL Location: Federal Plaza 211 S Clark St, Chicago, IL, United States Address: 211 S Clark St, Chicago, IL 60604 Time: 12-4 PM

HEY CHICAGO

standupforscience2025.org/chicago-il/

photo of illinois with text looking for illinois volunteers

☀️📣 Looking for a STATE LEAD and VOLUNTEERS to help us #standupforscience2025 in Illinois!

Know someone interested? Fill out this form: airtable.com/app4h5wUssMG...

#scienceforall #sciencenotsilence

Welcome to the Bluesky account for Stand Up for Science 2025!

Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!

#scienceforall #sciencenotsilence

If you are a neuroscientist, please use SFN's site to write to your reps about the importance of funding for science (they have letters ready to go, you can just use theirs or write/edit as you see fit): www.sfn.org/advocacy/adv...