Genuinely thrilled to share our new story with the world - an amazing collaboration with @profsharona.bsky.social and Bill Zagotta using their innovative FRET technique to study mitofusin conformational changes. Huge credit to Sophie Hurwitz for tackling this project. urldefense.com/v3/__https:/...
10.10.2025 18:31 — 👍 9 🔁 5 💬 2 📌 0Excited to share new work led by outstanding former grad student Kübra Akkaya! We show that Stearoyl-CoA Desaturases (SCDs) regulate intestinal stem and progenitor cell proliferation by balancing fatty acids, sustaining epithelial homeostasis and regeneration.
23.09.2025 12:55 — 👍 4 🔁 3 💬 1 📌 0
Hello! Ever wonder what's "talking to" your favorite transcript, but were too scared to ask? In our review in @cp-cellreports.bsky.social, @mardakheh.bsky.social and I highlight new RNA-focused tools for discovering RNA interactions across organizational scales. Checkit!
tinyurl.com/ydn6e3ac
We show that the liver cancer fibrolamellar carcinoma is characterized by increased mitochondrial calcium levels, which leads to inhibition of BCAA catabolism. Congratulations to all the authors, and many thanks to collaborators @lucasbsullivan.bsky.social @shaoenong.bsky.social
31.05.2025 06:24 — 👍 0 🔁 1 💬 0 📌 0
Our paper on regulation of BCAA catabolism by mitochondrial calcium signaling is out!
Mitochondrial calcium signaling regulates branched-chain amino acid catabolism in fibrolamellar carcinoma | Science Advances www.science.org/doi/10.1126/...
ATTENTION MITO-CALCIUM ENTHUSIASTS: there's a new game in town! This piece highlights a new paper by the Elrod Lab interrogating TMEM65’s role in mitochondrial calcium efflux. The De Stefani and Glancy labs have recently reported similar findings. Congratulations on this important discovery!
31.05.2025 05:59 — 👍 3 🔁 3 💬 0 📌 0
It's my great pleasure to present the next big preprint from SheqLab! An exciting application of our O-MAP platform that I hope will transform the study of nuclear architecture.
If you've ever wanted to dissect the subnuclear "neighborhood" around an individual locus, read on! (1/30)
