Molly Schumer

In this #Journal Club, @delvecchyo.bsky.social &Co discuss a study that mapped the genetic basis of hybrid incompatibility in swordtail fish, revealing #melanoma-causing gene interactions that reduce survival in natural hybrid populations.

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A reminder that the PhD program for EMBL is open for winter recruitment round. If you want to understand life at a molecular level and have a quantitative science (you don't have to have done biology - we love our mathematicians/physcists/chemists!) apply www.embl.org/about/info/e...

Building a community of PROPEL-affiliated programs at UCSF, U. Utah, UCSC, MUSC, U. Iowa, UW/Fred Hutch, OHSU, and Stanford!

There are unprecedented challenges for science, calling for bold action and collective effort. Training the next generation of scientific leaders has never been more important. Join us as we grow National PROPEL to answer this call. Learn more: propelscholars.org @propelscholars.bsky.social 🧪🧬🖥️🧵

I’m extremely honored to be a recipient of the NIH Director’s Pioneer Award!

Why some federal workers aren't scared by the threat of shutdown layoffs Some federal workers support the government shutdown, even as President Trump threatens to use this moment to lay off employees and cut funding to programs.

@jenna-m-norton.bsky.social “Every awful thing that would happen in a shutdown...is already happening.” This isn’t about partisanship. It’s about stopping the erosion of our public services. It’s time to protect the programs that serve our communities and stand up to authoritarianism. #StopTheScam

Letter Regarding Compact MIT Chapter of the American Association of University Professors October 6, 2025 Statement on the “Compact for Academic Excellence in Higher Education” MIT has been invited by the federal governmen...

I am proud of MIT, where our branch of AAUP has voted unanimously to endorse this statement urging MIT leadership and the MIT Corporation to reject the Compact wholesale
docs.google.com/document/d/1...

Over the weekend ICE abducted an NIH contractor when he showed up to a courthouse for his green card hearing. He is documented. His wife is a citizen.

He is also member of the skeleton crew of animal care staff that works through a shutdown, to ensure the health and wellbeing of research animals.

Happy to share work spearheaded by former grad student Colin Shew testing shared duplicated cis regulatory elements (CREs) using an MPRA. While we find some high effect CREs, collectively paralog differences represent modest effects accounting for observed gene expression divergence.

I want to try something again at #ASHG25 this year: I'll block some time on Thursday and Friday afternoons to meet with trainees who would be interested to chat on any topic.

I did this last year and it was great to meet a whole bunch of new people, at all career stages!

FlyBase Update – October 2025 The termination of the NIH/NHGRI FlyBase grant has placed the long-term sustainability of FlyBase at risk. However, thanks to the generous support of several key individuals and institutions, we are pleased to announce that FlyBase will remain operational through the coming year. We extend our deepest gratitude to Yukiko Yamashita, Cassandra Extavour, Hugo Bellen, Thom Kaufman, the Genetics Society of America / Drosophila Board, the Bloomington Drosophila Stock Center, an anonymous donor and the Wellcome Trust. We are especially thankful for a generous gift from Seemay Chou, Jed McCaleb, and The Navigation Fund. We also greatly appreciate the continued support from the broader Drosophila community – your donations and service fees have been vital in helping us stay afloat. Special thanks also go to Jessica Manning for her tireless administrative work at Harvard, to Ruth Lehmann, Hugo Bellen, and Paul Sternberg for advice and efforts, and to the Board of the European Drosophila Society for all their efforts. Sadly, we must also share that several long-standing FlyBase team members have recently moved on. We are immensely grateful to Susan Russo-Gelbart, Lynn Crosby, Gil dos Santos, Kris Broll, Victoria Jenkins, and TyAnna Lovato for their many years of dedicated service and contributions to FlyBase. Looking ahead, ensuring FlyBase’s sustainability beyond the next year – and successfully integrating with the Alliance – will require new funding sources. We kindly ask for your continued support: • European labs: Please consider contributing to the Cambridge, U.K. FlyBase group • U.S. and other non-European labs: Please consider contributing to the U.S. FlyBase groups • Both U.K. and U.S. FlyBase are working diligently to establish an invoicing system. We appreciate your continued patience. For more information on how to support us, please visit: Contribute to FlyBase wiki page https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase...
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila

Human-mediated land-use and climate change occur simultaneously, but how do they interact to shape adaptive dynamics? Super excited to share the first paper from the Kreiner lab, led by postdoc extraordinaire @rpineau.bsky.social

This is a breathtaking abuse of the law and power by the President of the United States.

America is on the brink of martial law.

Do not be silent.

California vows to ‘instantly’ cut funding to universities that cave to Trump ‘compact’ Governor Gavin Newsom urges schools not to sign ‘radical agreement’ to cuts to departments, students and speech Any California universities that sign the Trump administration’s proposed “Compact for Academic Excellence in Higher Education” will “instantly” lose their state funding, California governor Gavin Newsom said in a statement. The Trump administration on Wednesday offered nine prominent universities, including the University of Southern California, the chance to sign a “compact” that asks the universities to close academic departments that “purposefully punish, belittle, and even spark violence against conservative ideas”, limit the proportion of international undergraduate students to 15% , accept the administration’s definition of gender and ban the consideration of race or sex in hiring and admissions, in exchange for “substantial and meaningful federal grants”. Continue reading...

California vows to ‘instantly’ cut funding to universities that cave to Trump ‘compact’

"What is happening in this country is happening because science is bad for tyrants, and always has been"

It's official! We are moving to Stowers!
Very exciting opportunity to expand our studies of insect-plant interactions. We have many opportunities available in biochemistry, development, behavior, genetics, evolution, genomics, AI, and even pest control. Interested in any of these things? Reach out!

Another violent attack by an ICE officer on a civilian at 26 Federal Plaza—this time on a journalist, who had to be carried out on stretcher.

Another attack on the First Amendment, our neighbors, and our democracy.

I'm skimming, but this paragraph stood out:

Do you know ~60% of human SVs fall in ~1% of GRCh38? See our new preprint: arxiv.org/abs/2509.23057 and the companion blog post on how we started this project and longdust: lh3.github.io/2025/09/29/o.... Work with Alvin Qin

New paper alert!!!🚨 in our new study we find that Antarctic icefishes added a new module in their skulls during their adaptive radiation special shout out to @mayaranevesbio.bsky.social who led this project!

www.pnas.org/doi/10.1073/...

Delighted to contribute to an effort led by @omfishient.bsky.social, @jasonwilliamsny.bsky.social, @danielbolnick.bsky.social, @jbyoder.org, Susan Brennen, + Gisele Muller-Parker.

Petition link here:
laurenkuehne.github.io/grfpChanges/

@mollyschumer.bsky.social if the data is pre SPQR chemistry I would recommend fibertools. If it’s new data then you can use Jasmine from Pacbio, Andrew and I spent a fair amount of time looking at the Jasmine results and they look good. And it will all still work with downstream fibertools commands

What are people using for calling m6A from pacbio revio data? This is for analysis of fiberseq library. Any suggestions appreciated, we are newbies with m6A analysis!

Hello #fish 🐟 🐠 researchers and PIs of tomorrow! We would be excited to sponsor you for an Ecology, Evolution and Behavior (EEB) Presidential #Postdoc Fellowship application @michiganstateu.bsky.social. Application deadline is Nov 10, so get in touch soom!

#EndlessFishMostBeautiful

We are searching for a Forest Ecophysiologist (tenure track Assistant or Associate Professor) to join the Department of Forest and Conservation Sciences, University of British Columbia Faculty of Forestry. Please share! Details are here: ubc.wd10.myworkdayjobs.com/ubcfacultyjobs

1/ I’m Till Eckert, a ProPublica reporter. For the past 2 weeks, I’ve been going to the same NY immigration courthouse.

Nearly every time, I see ICE agents arresting immigrants. Today, a woman was slammed to the ground after begging officials not to take her husband away.

Thread 👇

Introgression and Parental Conflict Underlie Repeated Occurrences of Postzygotic Isolation Postzygotic reproductive isolation is often thought to accumulate as a byproduct of neutral divergence. Yet, it frequently evolves rapidly, in line with non-neutral evolution. A major driver of intrin...

I'm so proud of this work!!! It was an incredible amount of effort that started when I was trapped in a greenhouse during the pandemic and is only now seeing the light of day. Kudos to Megan, Hagar, & Pia!

We'd love to hear your thoughts!
www.biorxiv.org/content/10.1...

We're on a roll: Super proud of this paper lead by Dr. Megan Frayer & GS Hagar Soliman (with a major contrib from GS Pia Schwarz): Introgression and Parental Conflict Shape Repeated Occurrences of Postzygotic Isolation @hybridzones.bsky.social @hagarsoliman.bsky.social @pfschwarz.bsky.social

Please share with anyone who cares about NSF support for graduate students and take 30 seconds to sign and leave a comment.

The deadline for the 2025 Graduate Research Fellowship Program is about one month away and literally no one can apply. #NSFGRFP

jasonjwilliamsny.github.io/grfp2025/

C. elegans is a real animal and we set out to understand how it comes to have its distinctive biogeography. Its ancestral center of diversity is in the higher elevation forests of Hawaii. Its closest relatives are spread across east Asia. Did they travel from Asia? [Preprint 🧵]