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Lopes_Lab

@lopeslab.bsky.social

We use molecular & cell biology and single-molecule approaches to study DNA replication stress and its contribution to genome instability in cancer.

350 Followers  |  319 Following  |  16 Posts  |  Joined: 16.01.2025  |  1.9672

Latest posts by lopeslab.bsky.social on Bluesky

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One more appointment with great science in a few days, one click away ๐Ÿ‘‡

28.05.2025 19:55 โ€” ๐Ÿ‘ 8    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Exciting PhD project available in our lab (time sensitive)! ๐Ÿ‘‡

07.05.2025 12:10 โ€” ๐Ÿ‘ 10    ๐Ÿ” 15    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Exciting science ahead! Hope to see many of you online on Tuesday 6th (just connect, no registration needed)

01.05.2025 14:49 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

More exciting genome integrity research at the horizon. Register to receive alerts and marks for your calendar ๐Ÿ‘๐Ÿ‘‡

02.04.2025 21:25 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

yes, Zoom link (and QR code to register for e-mail alerts) are in the flyers ๐Ÿ‘

18.03.2025 08:58 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Andre Nussenzweig, Michele Pagano, @polosophie.bsky.social Evi Soutoglou, @nitikataneja.bsky.social Marco Tigano, @rubenvanboxtel.bsky.social. Chairs: @lopeslab.bsky.social @dimiccolab.bsky.social Hope to see many of you frequently online!

17.03.2025 23:13 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@alebrambati.bsky.social @cantorlab.bsky.social Raphael Ceccaldi @chowdhurylab.bsky.social @albertociccia.bsky.social Diego Dibitetto, @agagambus.bsky.social @kajastelab.bsky.social @peterlylab.bsky.social @martakova.bsky.social @fmattiroli.bsky.social Mate Maus @centromellone.bsky.social

17.03.2025 23:11 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Andre Nussenzweig, Michele Pagano, #polosophie.bsky.social Evi Soutoglou, #nitikataneja.bsky.social Marco Tigano, #rubenvanboxtel.bsky.social. Chairs: #lopeslab.bsky.social #dimiccolab.bsky.social Hope to see many of you frequently online!

17.03.2025 21:58 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30โ€™), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!๐Ÿ‘‡

17.03.2025 21:58 โ€” ๐Ÿ‘ 38    ๐Ÿ” 34    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1

Your lombard eye is infallible ๐Ÿ˜œ

04.02.2025 22:00 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Just landed back in the lab, after a few incredible days on the Alps! A wonderful opportunity to consolidate our projects, rethink our strategies, explore new ideas, blend as a team... and, above all, have a lot of fun! Proud of you guys... and certainly much stronger now! ๐Ÿ‘๐Ÿคฉ

03.02.2025 23:00 โ€” ๐Ÿ‘ 10    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Congrats Francesca, so well deserved! ๐Ÿ‘๐Ÿ‘

25.01.2025 01:32 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thanks, Annabel!

20.01.2025 08:30 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

a great conference, and a tribute to a great scientist and man ๐Ÿ‘‡

19.01.2025 22:58 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Project lead in our lab by @vcherdy.bsky.social with key collaborative contributions, mainly from @nitikataneja.bsky.social. Another important step forward, investigating how nuclear architectural components orchestrate the replication stress response throughout the nucleus!

19.01.2025 12:01 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Preview
Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels Mild replication interference is a consolidated strategy for cancer chemotherapy. Tolerance to mild replication stress (RS) relies on active fork slowing, mediated by transient fork reversal and RECQ1...

Landing on Bluesky by sharing the latest preprint from the lab: nucleoplasmic Lamin A/C modulates RECQ1-mediated fork restart upon mild genotoxic stress, by regulating heterochromatin marks and ADP-ribosylation levels at replication factories
www.biorxiv.org/content/10.1...

19.01.2025 12:01 โ€” ๐Ÿ‘ 26    ๐Ÿ” 8    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

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