Sebastian Kadener

“Remote and partial clocks expand the circadian neuronal network, driving widespread molecular rhythmicity in Drosophila” Circadian clocks orchestrate daily physiology and behavioral rhythms, yet the extent to which cells lacking canonical clock components exhibit robust temporal regulation remains unclear. Here we addre...

Our new paper is out on bioRxiv and we’re really excited about it!
www.biorxiv.org/content/10.6...

We show that circadian clocks in the fly brain are far more distributed than the classic view. Huge kudos to the authors, especially @inespatop.bsky.social and Anne, and to our collaborators!!

Congrats Anita!

But this is happening to people around us: foreign professors, teachers, students, postdocs, neighbors. And sometimes much worse. Please don’t assume this can’t happen where you live. And if you witness it, say something. Silence is complicity.

I never imagined something like this happening in Newton, MA. I’m not someone who casually throws around “racist,” but the apathy and lack of empathy truly shocked me. Again, this isn’t about me, I’m a citizen and safe.

Then she asked if I’d be in trouble under the new immigration policy, and said maybe she should call ICE on me. I calmly repeated her words out loud so others could hear. The store was full, people behind me, the cashier, others nearby, and no one said a word.That silence was what hit me hardest.

At Wegmans (Newton, MA) on Saturday, I had a minor altercation with a young woman over something trivial. I was polite. But once she heard my accent, she told me to “leave her country” because I wasn’t born here.

Sharing this not because I need support (I’m fine), but because we all need to be aware of how bad things are getting, especially for people who are foreign, “look foreign,” and/or have an accent, even in very progressive, very blue places. 🧵

Thanks!

Thanks!

Circular RNAs exhibit exceptional stability in the aging brain and serve as reliable age and experience indicators Kirio et al. demonstrate that circRNAs steadily accumulate in the aging fly brain due to their exceptional stability. Temperature exposure (29°C) further elevates select circRNAs, which remain high weeks later, underscoring their potential as markers of both age and past experiences.

Super excited our paper on circRNA stability in the brain and their use as life experience markers is out! @inespatop.bsky.social www.cell.com/cell-reports...

Tissue-like multicellular development triggered by mechanical compression in archaea The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...

Exciting paper by the Bisson lab @Archaeon_Alex . So happy to be a small part of it and congrats to all the authors! www.science.org/doi/10.1126/...

Leaving the nasty one-lettered place was harder than giving up carbs, but I did it! I’ve made it to the land of blue skies and good vibes. ✌️