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Tim Krischuns

@krischuns.bsky.social

Virologist | Influenza | Polymerases | RNA Viruses | PostDoc @HeidelbergUniversity @ChlandaLAB @Bioquant | former Institut Pasteur | Science

163 Followers  |  285 Following  |  6 Posts  |  Joined: 08.01.2025
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Posts by Tim Krischuns (@krischuns.bsky.social)

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Mosquitoes like Aedes aegypti spread viruses that cause major global diseases. We decided to have a closer look at a family of mosquito carbohydrate-binding proteins involved in infecting these vector species. We found some unexpected things 😁

Preprint out now 🦟🦟🦟

www.biorxiv.org/content/10.6...

13.02.2026 09:04 β€” πŸ‘ 33    πŸ” 17    πŸ’¬ 1    πŸ“Œ 1
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New week, new HUPs member spotlieght!

πŸ‘‹πŸ» Meet Jules Duruz, General Executive. He studies the behaviour of small marine invertebrates to better understand nervous system evolution. He values building a supportive, interdisciplinary postdoc community and especially enjoys HUPs networking events.

12.02.2026 10:43 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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New week, new HUPs member spotlight!

πŸ‘‹πŸ» Meet Magdalena Wierzbicka, Communication Manager & Event Coordinator. She works on the development of drugs targeting the blood–brain barrier in brain cancers. She enjoys connecting with fellow postdocs while exploring the many paths postdoc life can offer.

05.02.2026 11:03 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
HEALTH + LIFE SCIENCE ALLIANCE | Interinstitutional Postdocs

Together with colleague and friend Carl Herrmann @uniheidelberg.bsky.social, we are looking for a motivated postdoc with experience in organoid culture and data analysis (#bioinformatics), for a project in the @hlsalliance.bsky.social Joint Postdoc call.

www.health-life-sciences.de/opportunitie...

03.02.2026 11:03 β€” πŸ‘ 10    πŸ” 8    πŸ’¬ 0    πŸ“Œ 2
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Cryo-EM structure reveals how influenza A virus NEP binds the viral polymerase at a regulatory hotspot, coordinating RNA synthesis and nuclear export. Fantastic collaboration with @loiccarrique.bsky.social and Jon Grimes. www.science.org/doi/10.1126/...

24.01.2026 17:25 β€” πŸ‘ 54    πŸ” 27    πŸ’¬ 1    πŸ“Œ 0
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New week, new HUPs member!

πŸ‘‹πŸ» Meet Oscar O’Dwyer Lancaster-Jones, Treasurer of our network. He develops new methods for engineering heart tissue from many cells. He enjoys being part of a young, interdisciplinary network and helping shape something new at Heidelberg University.

22.01.2026 10:20 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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New week, new HUPs member!

πŸ‘‹πŸ» Meet Karel Mocaer, Vice-President of our network. She works with volume electron microscopy and complementary techniques to study the visual system of marine flatworms. She is passionate about building platforms that connect postdocs and help access career development!

15.01.2026 13:37 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Adaptation differences and mechanisms of influenza viruses to ANP32 proteins across species | Journal of Virology The influenza virus RNA polymerase is a heterotrimeric complex comprising the PB2, PB1, and PA subunits. It binds to the eight segmented genomic RNAs of the virus, each of which is encapsidated by nuc...

Adaptation differences and mechanisms of influenza viruses to ANP32 proteins across species journals.asm.org/doi/10.1128/...

05.01.2026 14:31 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

How does it behave for thicker chlamy lamella? πŸ‘‹

13.12.2025 09:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

For our English speaking members (and friends): the polls are in! As of March '26, we will have a new Board of Directors ("Vorstand"), as well as a new Advisory Board ("Beirat").

Our new president will be Prof. Sandra Ciesek (Frankfurt)! Cordial congratulations, Sandra πŸ’

Further board members ⬇️

05.12.2025 16:19 β€” πŸ‘ 13    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1

Last chace to register for this year's Influenza Update Meeting - and places are going fast. Don't miss out!

Looking forward to seeing you there, flu people

05.11.2025 13:17 β€” πŸ‘ 6    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Our new preprint is out πŸ₯³πŸ₯³πŸ₯³

Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence?

πŸ‘‡

03.11.2025 12:26 β€” πŸ‘ 111    πŸ” 47    πŸ’¬ 3    πŸ“Œ 2
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Mysteries of trafficking of the vRNP segmented genome and assembly of influenza A virus revealed by in situ cryo-ET!
πŸ”— rdcu.be/eMmct
We are very excited that our paper is finally out!
πŸŽ‰ Big congratulations to Moritz Wachsmuth-Melm and to everyone involved.

24.10.2025 08:11 β€” πŸ‘ 74    πŸ” 28    πŸ’¬ 1    πŸ“Œ 3
Abstract submission

🦠 Abstract submission for the 35th Annual Meeting of the Society for Virology is open!

Share your research with the virology community and help shape the scientific dialogue next year in Heidelberg.

πŸ• Deadline: Jan 4, 2026

πŸ”— virology-meeting.de/programme-ab...

#GfV2026 #virology #virologymeeting

22.10.2025 07:34 β€” πŸ‘ 15    πŸ” 14    πŸ’¬ 0    πŸ“Œ 2

Happens when cars are just seen as one mode of transportation and not religion πŸ˜‰

18.10.2025 20:29 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Dear scientific community,

I am looking for two postdoctoral structural biologists to join my group at the Department of Biochemistry, University of Oxford.

my.corehr.com/pls/uoxrecru...

my.corehr.com/pls/uoxrecru...

08.09.2025 15:16 β€” πŸ‘ 29    πŸ” 30    πŸ’¬ 2    πŸ“Œ 2

Very proud of this achievement. Lots of exciting work ahead - stay tuned!

16.07.2025 19:34 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Big personal news: Today I’ve started as Full Professor & Director of the Molecular Virology Department at Heidelberg University (@uniheidelberg.bsky.social). 1/4

01.07.2025 13:31 β€” πŸ‘ 21    πŸ” 2    πŸ’¬ 2    πŸ“Œ 2
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A new mural has been unveiled in the French city of Roubaix to mark #July4th.

(🎨 Judith de Leeuw)

04.07.2025 13:48 β€” πŸ‘ 2946    πŸ” 1015    πŸ’¬ 64    πŸ“Œ 87
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Old cytokine, new tricks: A refined model of interferon’s antiviral activity Interferon is a central component of the vertebrate antiviral immune response, thought to act through induction of hundreds of interferon-stimulated genes, with some redundancy. This Perspective highl...

Out now! A fresh perspective on interferon-mediated antiviral activity -- How many ISGs does it take to inhibit a virus? Perhaps far fewer than we think.

dx.plos.org/10.1371/jour...

09.05.2025 15:07 β€” πŸ‘ 44    πŸ” 13    πŸ’¬ 0    πŸ“Œ 0
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Repost appreciated:

Open #PhDposition in structural virology in my group! Join us in UmeΓ₯, πŸ‡ΈπŸ‡ͺ to uncover how arboviruses remodel the cellular interior. In situ #cryoET combined with #virology, #cellbiology, and #biophysics.

Deadline 4 May. More info: www.carlsonlab.se/join/

04.04.2025 08:06 β€” πŸ‘ 23    πŸ” 30    πŸ’¬ 1    πŸ“Œ 5

Bon voyage!

12.04.2025 10:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Training the Physician-Scientists of Tomorrow: Institut Pasteur MD-PhD Program In the face of global health crises and growing public health challenges, strengthening the links between scientific research (both fundamental and applied) and clinical practice has become essential....

πŸ“šπŸ©Ί We are launching our MD-PhD program to bridge clinical practice and scientific research. Our goal: training physician-scientists who can tackle global health challenges with agility and expertise.
#GlobalHealth #MedicalResearch

27.03.2025 13:28 β€” πŸ‘ 31    πŸ” 13    πŸ’¬ 0    πŸ“Œ 0
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I'm super happy that our story is now published!
πŸ“– www.science.org/doi/10.1126/...
But what changed compared to the original preprint?

Also, I feel i should post Movie 1 πŸŽ₯, that inspired the cover. Back when I did the original bluesky thread, movies were not available.

21.03.2025 14:09 β€” πŸ‘ 215    πŸ” 68    πŸ’¬ 7    πŸ“Œ 9

We're on the cover of @science.org this week. Awesome work by @florentwaltz.bsky.social. #CryoET is reaching crazy resolutions inside cells, and this is just the beginning. Fantastic interpretation of the proton motive force by @verenaresch.bsky.social. Always a pleasure making #SciArt with you!πŸ§ͺ🧢🧬🌾

20.03.2025 22:37 β€” πŸ‘ 308    πŸ” 69    πŸ’¬ 16    πŸ“Œ 2
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g-f-v.org/stellungnahm...

14.03.2025 16:15 β€” πŸ‘ 141    πŸ” 50    πŸ’¬ 4    πŸ“Œ 2
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Hundreds of #virologists queing for the dinner party of the #GfV2025 conference in #Hamburg. Thanks a lot to Thomas Dobner and his team for organizing a vibrant #conference of the #DACH society with terrific keynote speakers! πŸ™ The GfV board of directors wishes all participants a safe trip home! πŸ€—

07.03.2025 12:42 β€” πŸ‘ 26    πŸ” 3    πŸ’¬ 0    πŸ“Œ 2
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Many thanks to everyone involved in all our work and activities of our young GfV #jGfV.
Many members of the #jGfV Board are here in Hamburg

06.03.2025 15:05 β€” πŸ‘ 28    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Can coronaviruses continue to surprise us? This question was answered by keynote speaker Prof. David Veesler from Seattle on day 2.
(HMB)

05.03.2025 08:50 β€” πŸ‘ 13    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0