Sanjeev Herr

Shawn Hervey-Jumper, MD, (left) and Brain Nahed, MD, (right) pose for a photo with the award certificate.

Shawn Hervey-Jumper, MD, at the podium presenting his talk.

The big screen showing UCSF neurosurgeon Shawn Hervey-Jumper, MD, at the podium delivering his presentation.

Congratulations to @ucsfhealth.bsky.social neurosurgeon @herveyjumper.bsky.social on receiving the Guha Award from the AANS/CNS Section on Tumors & @neuroonc.bsky.social! 🎉 This award recognizes his lab’s research advances in cancer neuroscience and his dedication to mentoring. #2025CNS #CNSConnects

The Los Angeles skyline and palm trees below a banner for the 2025 CNS Annual Meeting being held October 11-15, 2025.

We’re excited to be in sunny L.A. for #2025CNS! Check out all the incredible work that our faculty, residents, and medical students are doing: neurosurgery.ucsf.edu/news/ucsf-ne...
@herveyjumper.bsky.social @ucsfcancer.bsky.social @ucsfhealth.bsky.social #Neurosurgery

How to disconnect therapy-resistant tumor networks in glioblastoma?

In our paper, online @Cancer Discovery, we built an anti-tumor microtube (TM) screening pipeline and found that Protein Kinase C activators disrupt TMs, silence Ca²⁺ “pacemakers” and boost radiotherapy.
doi.org/10.1158/2159...

I’m thrilled to report on work I led with Dr. Shawn Hervey-Jumper and Dr. Todd Hollon which shows that we can forecast where glioblastoma will recur even at time of initial resection.

It’s wonderful to see all the work I conducted during my research year @neurosurgucsf.bsky.social come together!

Graphic showing an MRI scan of a low grade glioma below a headline that says, How AI is Changing Brain Tumor Surgery. Subheading says: High-tech imaging approaches allow neurosurgeons to interpret tissue samples during surgery to remove previously invisible malignant cells.

Quote card showing Shawn Hervey-Jumper, MD, a UCSF neurosurgeon and the Mitchel S. Berger, MD Endowed Professor of Neurosurgery, during an awake brain surgery. He is quoted saying: With this new technology, we can deliver safer, more complete tumor resections.

UCSF neurosurgeon @herveyjumper.bsky.social & his @umich.edu colleagues have developed an intraoperative tool called FastGlioma that uses AI to help neurosurgeons see in real-time where tumor cells have infiltrated brain tissue. 🧪 braintumorcenter.ucsf.edu/news/how-ai-...
@ucsfcancer.bsky.social

See highlights of @ucsfradonc.bsky.social participation at the 2025 @astro-org.bsky.social conference starting tomorrow: cancer.ucsf.edu/news/2025/09... #ASTRO2025 #UCSF

If Anti-Seizure Meds Don’t Work for Epilepsy, Can Surgery Help? Vikram Rao, director of the UCSF Epilepsy Center, discusses why a third of seizure patients don’t respond to medication and the promising new surgical and technological treatments available.

Anti-seizure meds don’t work for 1 in 3 epilepsy patients. UCSF experts are closing the gap with surgery and breakthrough devices that can change lives. tiny.ucsf.edu/HzE2SS

Durably reducing conspiracy beliefs through dialogues with AI Conspiracy theory beliefs are notoriously persistent. Influential hypotheses propose that they fulfill important psychological needs, thus resisting counterevidence. Yet previous failures in correctin...

Personalized conversations with a trained #AI chatbot can reduce belief in conspiracy theories, according to a 2024 Science study.

The findings, which challenge the idea that such beliefs are impervious to change, point to a tool for combating misinformation. https://scim.ag/47uE1uz

Great talks and even more interesting and engaging discussion! Fantastic start to the think tank!

From Chronic Pain to Parkinson’s, 4 Ways DBS is Changing Care UCSF looks back on four ways it pioneered deep brain stimulation with the help of federal funding, helping patients with Parkinson’s Disease, chronic pain, depression, and more.

A breakthrough method for personalized deep brain stimulation (DBS) is improving Parkinson’s treatment, and could one day be applied to depression and other conditions. "Tailoring these treatments to the person’s neural signature is really the key,” Dr. Edward Chang says. https://ucsfh.org/45HdiIr

What an incredible month it has been completing my sub-I at @neurosurgucsf.bsky.social ! I learned so much, met so many incredible people, and I had a great time doing it. I am truly grateful to have had this opportunity. #Neurosurgery #Match2026

Peacock feathers can be lasers Tail feathers can emit narrow beams of light, a first in the animal kingdom

Peacocks have a secret hidden in their brightly colored tail feathers: tiny reflective structures that can amplify light into a laser beam. scim.ag/3UEM2oQ

We’re honored to be named among the top two neurosurgery programs nationwide and the Best in the West by @usnews.com! 🎉 It's a privilege caring for our patients and their families, and we thank our entire team for hard work and dedication. @ucsfhealth.bsky.social www.ucsfhealth.org/lp/us-news-2...

Graphic that depicts an overview of the study in which UCSF researchers modeled and optimized DBS settings to improve walking in patients with Parkinson's, identifying key insights abut the neurophysiology of walking along the way.

A new study led by @doriswang.bsky.social's lab developed a systematic way to quantify key aspects of gait in patients with #Parkinsons and used machine learning to identify personalized deep brain stimulation (DBS) settings to improve walking: www.ucsf.edu/news/2025/07...
@ucsfhealth.bsky.social 🧠📈

Our latest research on the neural basis of speech-motor sequencing is now published in @nathumbehav.nature.com! Check out this high-level explainer video and read the full paper here: t.co/YKJlabr3yb

Electrocorticographic Detection of Speech Networks in Glioma-infiltrated Cortex https://www.biorxiv.org/content/10.1101/2025.07.04.663249v1

Graphic showing microscopy image in the background and photos of the publication's lead authors (L to R): Takahide Nejo, PhD (first author), Saritha Krishna, PhD (second author), Shawn Hervey-Jumper, MD (co-senior author), Hideho Okada, MD, PhD (co-senior author). Text includes publication citation: Glioma-neuronal circuit remodeling induces regional immunosuppression. Nejo T et al. (2025) Nat Comm. 16(1): 4770.

In @natcomms.nature.com, Takahide Nejo, PhD & the Okada lab worked with Saritha Krishna, PhD & @herveyjumper.bsky.social to show how the complex interaction between #glioblastoma and immune cells suppresses pro-inflammatory immune responses and drives tumor growth: www.nature.com/articles/s41... 🧪

Award graphic announcing Shawn Hervey-Jumper, MD, as the winner of the 2025 Abhijit Guha Award from the Section on Tumors of the AANS/CNS and the Society of Neuro-Oncology.

Congratulations to @herveyjumper.bsky.social for being named this year's recipient of the Abhijit Guha Award! 🎉 This award recognizes his accomplishments as a neurosurgeon-scientist and his role as a mentor in the field of neuro-oncology. #SNO2025 @neuroonc.bsky.social @ucsfcancer.bsky.social

New paper with @herveyjumper.bsky.social and Vardhaan Ambati! It shows that causal (DCS+) language cortex in glioma patients has greater ECoG information encoding (higher entropy and linguistic decoding). DCS+ sites showed stronger oscillations and high gamma, enabling prediction of DCS sites.

NEW content online!

The actor Harvey Fierstein, with short gray hair and wearing a blue suit and a colorful bow tie, holds a Tony Award, touching his hand to his chest. Photo by Sara Krulwich/The New York Times

Harvey Fierstein, who has been a steady presence onstage and backstage over the course of 40 years, received a lifetime achievement Tony Award on Sunday night. Follow live updates. nyti.ms/445CFUN

Heading to the airport to catch a plane to Allegheny for my first neurosurgery Sub-I. There are not enough words to express the gratitude that I have for my research year in the Hervey-Jumper lab. Incredible group, work and mentorship. Feeling blessed.

UCSF neuro-oncologist Susan Chang, MD, FASCO, stands in front of the stage at the 2025 ASCO Annual Meeting wearing her ASCO medal. The ribbons on her meeting badge indicate that she has been a member of the society for 30 years and that she is a Fellow of ASCO.

Congratulations to @ucsfhealth.bsky.social neuro-oncologist Susan Chang, MD, on being named a Fellow of the @ascocancer.bsky.social for her dedication to volunteer service efforts within oncology that have benefitted the patients and the field! 🎉 #ASCO25 @ucsfcancer.bsky.social

Eric Small with UCSF peers, Drs. Mi-Ok Kim, Patrick Ha, and Hyunseok Kang

Peers from @ucsanfrancisco.bsky.social celebrate with Dr. Eric Small @ucsfhealth.bsky.social at #ASCO25 as he prepares to assume his role as President of @ascocancer.bsky.social for the 2025-2026 year ascopost.com/issues/may-2...

Thrilled for this opportunity to present on the work I have been doing this past year in the lab of Dr. Hervey-Jumper! @neurosurgucsf.bsky.social

June 1st at 9:45 am CT Sanjeev Herr, BS, MS @sanjeevherr.bsky.social @ucsfhealth.bsky.social presents at #ASCO25 Clinical Science Symposium on Refining Local Therapies in Central Nervous System Oncology at Symposium during the @ascocancer.bsky.social annual meeting in Chicago.

June 1st at 9:45 am CT Sanjeev Herr, BS, MS @sanjeevherr.bsky.social @ucsfhealth.bsky.social presents at #ASCO25 Clinical Science Symposium on Refining Local Therapies in Central Nervous System Oncology at Symposium during the @ascocancer.bsky.social annual meeting in Chicago.
lnkd.in/gkF6dRDT

Tissue samples were from healthy cortex (e.g., insular tumor resection), allowing transcriptionally defined neuronal subclasses, including numbers of glutamatergic + GABAergic neurons. This link better enables aperiodic (1/f) slope from EEG/ECoG to be used as a surrogate for cortical excitability.

New paper with Shawn Hervey-Jumper's lab! As only PART of this project, it validates the relationship between aperiodic slope and cortical excitability using ECoG and single-nuc RNA sequencing in humans. Tissue samples with more excitatory neurons showed flatter aperiodic slope.

Aperiodic neural dynamics define a novel signature of glioma-induced excitation-inhibition dysregulation https://www.biorxiv.org/content/10.1101/2025.05.23.655626v1

Edward Chang, MD, Chair of Neurosurgery at UCSF.

Big News: We are proud to announce that @ucsanfrancisco.bsky.social's Chair of Neurosurgery, Edward Chang, MD, has been elected to the @nasonline.org — one of the highest honors given to American scientists! 🎉