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Anne Goriely

@agoriely.bsky.social

Human genetics, rare disease and de novo variant detection | selfish selection | mosaicism | cell competition | paternal age effects | spermatogenesis | testis @University of Oxford @MRC- WIMM

718 Followers  |  749 Following  |  1 Posts  |  Joined: 17.12.2023
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Posts by Anne Goriely (@agoriely.bsky.social)

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#ScientistSpotlight πŸ§ͺ

This week we’re featuring Hans Ng, a postdoctoral researcher in the Anne Goriely Lab at the #MRCWIMM.

@sciencehans.bsky.social @agoriely.bsky.social @medsci.ox.ac.uk @rdm.ox.ac.uk

13.01.2026 10:09 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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In-person tickets open: The Shape of Shells 🐚

https://gres.hm/shape-shells

Seashells, built by molluscs layer by layer, follow simple mathematical rules that create beautiful self-similar forms. Prof Alain Goriely* explains how we get various shapes, spines & wrinkles

*also of Oxford Mathematics

27.12.2025 10:00 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Expectations for papers performing Mendelian randomization analyses

Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...

We are trying to set standards -

17.07.2025 18:45 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Challenge of the best kind. Many thanks to my co-lead Dr Minna Jeffery & fellow grant holders @agoriely.bsky.social @lisahinton.bsky.social and our integral co-production panel: Marysia Price-Nowak, Arti Patel, Francesca Wicks, Jon Wells, Dr Shwetha Ramachandrappa, Alexa Gummow & others who helped!

15.07.2025 11:06 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Congratulations to @agoriely.bsky.social on being awarded the Spinoza chair by @amsterdamumc.bsky.social πŸŽ‰

In June, Prof Goriely will give her Spinoza lecture on how new genetic mutations arise in the testes, their increase in frequency as men age, and how they can lead to serious genetic diseases.

21.05.2025 08:34 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
International Women's Day at the MRC WIMM
YouTube video by MRC Weatherall Institute of Molecular Medicine International Women's Day at the MRC WIMM

For International Women's Day tomorrow, we asked some of our female scientists, including @agoriely.bsky.social & @sumanasharma.bsky.social, to reflect on why this day is so important, the barriers and biases women can face in their careers, and which women have inspired them.

#IWD2025

07.03.2025 12:10 β€” πŸ‘ 10    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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A fantastic trip to King George V college in Southport for #RareDiseaseDay for our "We are all Mutants" workshop! Students discussed the criteria for inclusion of diseases in the newborn screening program & assessed the ethical dilemmas with whole genome sequencing. #Genomics @cpmoxford.bsky.social

03.03.2025 16:55 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 1    πŸ“Œ 3
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Learning to catch a wave between sessions #lornegenome #lornegenome2025

17.02.2025 04:50 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Nature should have a bluesky button!

25.01.2025 08:27 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Official lab account @gorielylab.bsky.social
Follow us there if you want to know what we are up to!! 🧬

24.01.2025 13:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Funding awarded for new theatre-based community engagement project Alison Kay and Anne Goriely, together with Minna Jeffery (St. Anne’s College) and Lisa Hinton (Nuffield Dept. of Primary Care Health Sciences), have won an award from the University of Oxford’s PCER F...

NEW: @genomics-ali.bsky.social & @agoriely.bsky.social have been awarded funding for a new community engagement project, which will use theatre to explore public perception of a new form of genetic testing.

Read more: buff.ly/4jkEens

This project is also supported by @cpmoxford.bsky.social

23.01.2025 11:34 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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a couple of cartoon characters standing next to each other with one wearing a purple earring Alt: a couple of cartoon characters standing next to each other with one wearing a purple earring

πŸ“£ Big news! Our tag-team effort on common variants in rare neurodevelopmental conditions is now out in Nature πŸ“£

Co-first authoring with the brilliant Qinqin HuangπŸŒŸβ€”proof that teamwork does make the dream work. πŸ’ͺ www.nature.com/articles/s41...

20.11.2024 16:03 β€” πŸ‘ 158    πŸ” 47    πŸ’¬ 11    πŸ“Œ 7
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Somatic mutation and selection at epidemiological scale As we age, many tissues become colonised by microscopic clones carrying somatic driver mutations ([1][1]–[10][2]. Some of these clones represent a first step towards cancer whereas others may contribu...

Resharing here a recent X post. In this preprint, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people. 1/ www.medrxiv.org/content/10.1...

20.11.2024 14:27 β€” πŸ‘ 88    πŸ” 38    πŸ’¬ 2    πŸ“Œ 5
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To all you scientists in training: there’s a podcast that explores the creative process of amazing scientists. Check it out and please subscribe!
Apple Podcasts: podcasts.apple.com/us/podcast/n...
Spotify: open.spotify.com/show/6berzd2...

04.09.2023 20:36 β€” πŸ‘ 25    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Doing good science is 90% finding a science buddy to constantly talk to about the project.

09.11.2024 22:53 β€” πŸ‘ 882    πŸ” 215    πŸ’¬ 22    πŸ“Œ 65

Inspired by the other amazing starter packs - here's one for cancer researchers!

I tried to make this broad - from immunology to genomics to cell biology and so much more..

This list also includes organizations & institutes supporting cancer researchers πŸ§ͺπŸ”¬βš•οΈπŸ©Ί

Hope its useful!

go.bsky.app/FEoaJMc

14.11.2024 21:44 β€” πŸ‘ 363    πŸ” 127    πŸ’¬ 99    πŸ“Œ 15

I couldn't spot a starter pack for rare disease / clinical genomics, so I started one: go.bsky.app/SUWZ9Hw

Very much a work in progress, and biased by who I have already found here, so please suggest people to add! Self-nominations encouraged.

#ClinicalInformatics #genomics #bioinformatics πŸ–₯️🧬

15.11.2024 10:29 β€” πŸ‘ 155    πŸ” 46    πŸ’¬ 38    πŸ“Œ 5