Anne Spurkland

GATHeR: Graph-based Accurate Tool for Immunoglobulin HEavy- and Light-chain Reconstruction Recovering full-length, paired B-cell receptor (BCR) sequences from scRNA-seq reads remains difficult, especially in naive and memory B cells where immunoglobulin transcripts are sparse. Current metho...

New BCR reconstruction tool for scRNA-seq: assembles full heavy & light chains and annotates constant regions. Check it out:
www.biorxiv.org/content/10.1...

#scRNAseq #immunology

Congenital rubella syndrome and autism spectrum disorder prevented by rubella vaccination--United States, 2001-2010 - PubMed We estimate that rubella vaccination prevented substantial numbers of CRS and ASD cases in the United States from 2001 through 2010. These findings provide additional incentive to maintain high measle...

MMR vaccines do not cause autism (see my 🧵 of studies)

At the same time, one potential cause of autism is rubella, which is *prevented* by MMR vaccines.

Which means...vaccines may actually help prevent autism.

🧵

pubmed.ncbi.nlm.nih.gov/21592401/

In the bookshop this morning:

PARENTS: “Okay, we’re leaving now.”

CHILD: *pulls another book from the shelf and sits down *

CHILD: “Then I guess this is goodbye.”

PNAS Special Feature. Reimagining Science Communication in the COVID Era and Beyond.

The PNAS Reimagining Science Communication in the COVID Era and Beyond Special Feature advocates for a paradigm shift in science communication, from traditional, top-down dissemination to participatory and inclusive approaches. Explore the Special Feature: www.pnas.org/topic/575

screenshot of a figure from the article, showing the chimeric composition of FCoV-23, with FCoV-1 backbone and spike from CCoVII

A lab is not required to generate chimeric coronaviruses, with a spike of a different virus: they can emerge naturally ▫️1/2

(from newly published paper by Attipa & @amandatron89.bsky.social et al.; preprinted in 2023)
www.nature.com/articles/s41...

What has always irritated me about this debate - and what I discuss in this piece - is how the lab leak has never had a shred of evidence supporting it. People are using the same arguments today that they were in 2020.

Meanwhile, zoonosis has only gotten more likely over time.

Sviktende vitenskaps­journalistikk Det handler ikke om å kneble kontroversielle teorier, men journalistisk ansvar og vitenskapelig redelighet.

Sviktende vitenskaps­journalistikk

"Likevel trakk flere bokanmeldelser frem Bratlies vitenskapelige analyse som «solid». Dette vitner om lavt kunnskapsnivå og sviktende kildekritikk i redaksjonene."

Vaccine advisory committees and transparent practices Why changes to ACIP are concerning.

I have so busy at work of late so had no extra capacity to write but managed to pen this over the weekend discussing changes to ACIP and my concerns for vaccine uptake and vaccine hesitancy -

"The lab leak hypothesis is nothing more than a “god of the gaps” argument that attempts to find holes in the zoonosis hypothesis, but without managing to come up with a plausible scenario itself."

People familiar with debunking creationism are not falling for that lableak crap 😅

Good read 🔽

The documentary movie Blame wins the audience award at Turin film festival.

I think it resonates with audiences, because it offers something almost lost in today's world.

A calm, factual story about the origin of SARS-CoV-2.

Can't wait for more people to see it!

www.blame-documentary.com

En kritisk anmeldelse av "Mysteriet i Wuhan - Jakten på covid-pandemiens opphav" av Sigrid Bratlie En bok fylt av selvmotsigelser, cherry-picking av data, konspiratorisk argumentasjon og grove beskyldninger som bidrar til å svekke tillit til forskning og bidra til å gjøre verden mindre trygg i møte...

En bok fylt av selvmotsigelser, cherry-picking av data, konspiratorisk argumentasjon og grove beskyldninger som bidrar til å svekke tillit til forskning og bidra til å gjøre verden mindre trygg i møte med neste pandemi.

Les min anmeldelse og kritiske gjennomgang.

tjomlid.com/en-kritisk-a...

En kritisk anmeldelse av "Mysteriet i Wuhan - Jakten på covid-pandemiens opphav" av Sigrid Bratlie Molykelærbiolog Sigrid Bratlie kom nylig ut med sin bok "Mysteriet i Wuhan", og jeg møtte henne til debatt på Wonderful World – den nordiske filosofi og vitenskapsfestivalen i Stavanger i slutten av m...

Hvis du gidder å lese denne, er du god. Men jeg har skrevet en ganske omfattende, kritisk analyse av Sigrid Bratlie sin bok "Mysteriet i Wuhan". Håper du finner det interessant!

tjomlid.com/en-kritisk-a...

This is truly BRILLIANT science communication—clear, compelling, & convincing while also fast, funny, & entertaining

Like most of those working in science & public health, based on the best available evidence I believe Covid was zoonotic in origin—& this superb episode makes me even more convinced

Jeg tror man får vaksinen mot helvetesild dekket når det er i forbindelse med forventet svekket immunforsvar pga behandling mot kreft o.l.? Det ville iallefall ikke vært urimelig.

Kjempesøte!!

We were just notified that our contract to UCSD and Scripps Research to support wastewater surveillance in San Diego (searchcovid.info) was terminated immediately for the same reasons 👇.

That means no more genomic wastewater surveillance, and our proposed extensions to measles, Hep A, others, gone.

Ja, i Vestmarka mellom Semsvannet og Gupu.

Fra skogtur høsten 2024. Kan ikke engelske navn på honning sopp og kjuke. Artsorakelet kan kanskje hjelpe.

A group of brown mushroom i green surroundings

A group of grey mushrooms growing on a dead birch

A group of young mushrooms growing on a dead birch

Four chatarelles on the forest floor.

More mushrooms for you...

36 Hours in Oslo (Published 2023) The Norwegian capital is refashioning itself into a major cultural destination, with new museums, daring architecture, intriguing restaurants and myriad ways to celebrate the outdoors – even in the he...

Oslo is a nice town to visit. NYT made this overview in 2023 for how to spend 36 h in Oslo. Imagine what you experience if you had many more hours available here: www.nytimes.com/interactive/...

We are particularly interested in the SH2D2A gene encoding the adapter molecule TSAd. Check out our recently uploaded preprints on BioRxiv to see what we have been working on lately: www.biorxiv.org/search/%2522...

Immunobiology - Institute of Basic Medical Sciences The focus of the Immunbiology Laboratory is immune receptor biology and how this relates to the molecular mechanisms involved in autoimmune disease and cancer.

My group is part of the Immunobiology lab at the Department of Molecular Medicine, Institute of Basic Medical Sciences. The new PhD student will be part of this larger environment www.med.uio.no/imb/english/...

PhD-research fellowship in Molecular Immunology (276280) | University of Oslo Job title: PhD-research fellowship in Molecular Immunology (276280), Employer: University of Oslo, Deadline: Friday, March 21, 2025

A 3 year #PhD research fellowship in molecular immunology is available in my lab in Oslo, Norway. We focus on the role of adaptor molecules in #signaling in #Tcells. (Oslo has great opportunities for out doors activities). #immunosky www.jobbnorge.no/en/available...

Probably you've already thought of this but NOW is the time to stockpile chemicals, pipette tubes, kimwipes, parafilm, gloves, agar, sharpies and post-it notes.

Spend from your grants while they still exist.

🧪⚗️🧫🥼📁🖇️📓✏️

Me too

I got laid off today, with the rest of 18F.

18F was an elite federal software shop. We made gov't websites work better, more efficiently for the American people. We saved taxpayers from getting screwed over by contractors. And were fired for it.

We made this website to tell our story:
18f.org

Ending virology and vaccine research is far more dangerous than virology and vaccine research itself.

We can mitigate risks in the lab, but we can’t mitigate the catastrophic risk of being unprepared and defenseless against emerging viruses.

Bluesky Starter Packs - Bluesky Directory Browse a list of Bluesky Starter Packs. Discover and connect with your community on Bluesky

Check the immunology starter packs here: blueskydirectory.com/starter-pack...

På Storfotens hjemmeside har vi samlet endel adresser til skobutikker med store sko: www.storfoten.no/category/sko...

I kommentarfeltet under NRK-saken fra lørdag kom jeg over denne nettsiden: thedragshoes.com