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Richard White

@richardwhite321.bsky.social

Prof @LSHTM. Science for better tuberculosis policy & practice, vaccines. Co-Author 'Intro to Infectious Disease Modelling' rb.gy/ztlw9u How I got here bit.ly/4gbQd4J (skip to ~8:00) Amateur choir member: eg rb.gy/a1vvt

287 Followers  |  160 Following  |  39 Posts  |  Joined: 29.11.2024  |  2.1357

Latest posts by richardwhite321.bsky.social on Bluesky

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Excerpts from Copenhagen: The UNION World Conference on Lung Health 2025 Each year, many LSHTM TB researchers participate in the UNION World Conference on Lung Health, the world's largest conference on TB and lung health. This year, the conference takes place in

Join us ๐Ÿ“† 9 Dec โฐ 12.45 @tb-lshtm.bsky.social seminar
Free & Open to all
@kchorton.bsky.social @richardwhite321.bsky.social @reinhouben.bsky.social @dopapus.bsky.social @laragosce.bsky.social @danieljgrint.bsky.social

tinyurl.com/2s4y3jcd

25.11.2025 12:38 โ€” ๐Ÿ‘ 5    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

With huge thanks to all the tutors, students and the @gatesfoundation.bsky.social for making this all possible!

24.11.2025 13:51 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Another successful "Intro to TB Modelling" course in Copenhagen at #WLHC2025. Over 70 joined to learn about TB modelling!

Followed by the now-traditional TB Modelling and Analysis Consortium social, which was also very well-attended and a lot of fun.

24.11.2025 13:51 โ€” ๐Ÿ‘ 12    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
2026-27 Project (Sumner & Clark & Grint) - MRC London Intercollegiate Doctoral Training Partnership Studentships Mathematical modelling and clinical trial simulation of TB prevention SUPERVISORY TEAM Supervisor Dr Tom Sumner...

#5 Mathematical modelling and clinical trial simulation of TB prevention
mrc-lid.lshtm.ac.uk/2026-27-proj...
with Tom Sumner, @raclark18.bsky.social & @danieljgrint.bsky.social

18.11.2025 14:49 โ€” ๐Ÿ‘ 1    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Information for applicants - MRC London Intercollegiate Doctoral Training Partnership Studentships MRC LID studentship information for applicants How to Apply Projects Studentship funding Studentship options Studentship...

@lshtm-tbmod.bsky.social is offering multiple PhD opportunities through MRC LID, deadline 14 Jan. More details: mrc-lid.lshtm.ac.uk/applicants/
Projects include
#1 TB & screening
#2 TB & climate change
#3 TB & vaccines
#4 TB & influenza
#5 TB & prevention
@cmmid-lshtm.bsky.social @lshtm.bsky.social

18.11.2025 14:49 โ€” ๐Ÿ‘ 7    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Whatโ€™s a #UnionConf without the TB modelling course? Packed room again for a long day of intro to modelling.
@lshtm-tbmod.bsky.social @tb-mac.bsky.social #WCLH2025 #TBSky

18.11.2025 10:28 โ€” ๐Ÿ‘ 17    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
2026-27 Project (Clark & White) - MRC London Intercollegiate Doctoral Training Partnership Studentships How should countries deliver new TB vaccines when risk factors are considered? SUPERVISORY TEAM Supervisor...

#3 How should countries deliver new TB vaccines when risk factors are considered?
mrc-lid.lshtm.ac.uk/2026-27-proj...
with @raclark18.bsky.social & @richardwhite321.bsky.social

18.11.2025 14:49 โ€” ๐Ÿ‘ 1    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Modelling Like an Experimentalist Dahlin etย al. (2024) apply experimental thinking to a model of mosquito-borne disease transmissions.

"Validate With Simulated Truth: A first habit is to test whether an analytical pipeline can recover known conditions."

Very good advice below. So much COVID nonsense (e.g. 'immunological dark matter') basically came down to a non-identifiable model that hadn't been properly tested.

09.11.2025 21:18 โ€” ๐Ÿ‘ 49    ๐Ÿ” 6    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 2
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Projects - MRC London Intercollegiate Doctoral Training Partnership Studentships 2026-27 MRC LID POTENTIAL RESEARCH PROJECTS MRC LID is offering 40 distinct potential projects for...

Excited to say that we have a PhD project out on our age-sex research - looking at combinations of #AMR. With the fabulous @jodi-lindsay.bsky.social and Lanre Edun! Do get in touch for more information!

mrc-lid.lshtm.ac.uk/2026-27-proj...

10.11.2025 16:05 โ€” ๐Ÿ‘ 1    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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UK to put 250,000 lives at risk from HIV, TB and malaria with aid cuts Exclusive: The UK is expected to pledge ยฃ850m to the Global Fund to Fight Aids, TB and Malaria โ€“ a cut of 15 per cent โ€“ despite previous assurances that funding would be protected

Ahead of The Union World Conference on Lung Health, Katherine Horton provides @the-independent.com with insights into the devastating impact of the funding cuts on global health, particularly tuberculosis.

Be sure to read about the threat of UK aid cuts: www.independent.co.uk/news/uk/poli...

10.11.2025 21:41 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Climate change and tuberculosis: an analytical framework Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...

Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease
www.thelancet.com/journals/lan...

31.10.2025 09:12 โ€” ๐Ÿ‘ 22    ๐Ÿ” 18    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Announcement Awardees | TBVI Awards 2026 - TuBerculosis Vaccine Initiative Announcement Awardees | TBVI Awards 2026

โœจ Iโ€™m so honoured to have been awarded one of this yearโ€™s TBVI Awards! โœจ

Iโ€™m truly grateful for this recognition and excited for the opportunity to showcase my research at the TBVI Annual Meeting in January 2026.

#TBVI #tuberculosis #vaccines

tbvi.eu/announcement...

28.10.2025 13:24 โ€” ๐Ÿ‘ 9    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative Undernutrition is a key driver of the global tuberculosis epidemic, increasing the risk of people developing tuberculosis disease and of poor outcomes in those who do.1 Each year, WHO publishes estima...

โ€œWow, I saw in the last GTB report undernutrition is much less important for TB than we previously thoughtโ€ I hear you sayโ€ฆ
Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition โ€“ see our latest comment here: www.thelancet.com/journals/lan...

28.10.2025 09:44 โ€” ๐Ÿ‘ 7    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Impact of fluoroquinolone resistance on the cost-effectiveness of empiric treatment for multidrug- or rifampicin-resistant tuberculosis The WHO recommends the bedaquiline, pretomanid, and linezolid (BPaL) regimen with the additional fluoroquinolone antibiotic moxifloxacin (BPaLM) for initial treatment of multidrug- or rifampicin-resis...

When fluoroquinolone resistance status is unknown, empirical use of BPaLM (adding moxifloxacin to BPaL) is cost-effective as a replacement for BPaL even with high fluoroquinolone resistance levels! ๐Ÿฆ ๐Ÿ’Š

doi.org/10.1371/jour...

20.10.2025 18:47 โ€” ๐Ÿ‘ 12    ๐Ÿ” 12    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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A global analysis of patterns of tuberculosis exposure and transmission Tuberculosis (TB) is a major public health concern and the leading infectious cause of mortality globally. The disease exhibits strong prevalence patterns by age and sex, but the implications of these...

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries.

bit.ly/4nbV492

12.10.2025 12:51 โ€” ๐Ÿ‘ 16    ๐Ÿ” 17    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad:

idm.uct.ac.za/media/739223

09.10.2025 11:28 โ€” ๐Ÿ‘ 82    ๐Ÿ” 40    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 3
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About half of people with #TB are asymptomatic (aTB). Calls have been made to stratify treatment and estimate incidence based on aTB case definitions

In this preprint we raise concerns that symptoms are an inadequate & inconsistent classifier of TB state, being highly influenced by context

โฌ‡๏ธlink

15.08.2025 18:02 โ€” ๐Ÿ‘ 12    ๐Ÿ” 4    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
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Do no harm - re-evaluating the risks of overtreatment in community-wide tuberculosis screening Background Community-wide screening is a crucial strategy to end tuberculosis (TB), but a common concern is potential harm from overtreatment following false positive diagnoses. However, current refer...

In a new preprint (NOT PEER REVIEWED) we continue to explore the challenge of overtreatment in community screening. It seems the benefits of TB treatment far outweigh the harms, especially once we accept that sputum culture is not perfect. Important food for thought. www.medrxiv.org/content/10.1...

07.10.2025 09:17 โ€” ๐Ÿ‘ 12    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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New approaches for modelling tuberculosis transmission in low incidence settings at University of Bristol on FindAPhD.com PhD Project - New approaches for modelling tuberculosis transmission in low incidence settings at University of Bristol, listed on FindAPhD.com

PhD opportunity: New approaches to modelling TB transmission in low-incidence settings.
Supervised by Ellen Brooks-Pollock (Bristol), me (Bath) & Rajeka Lazarus (Bristol)
Apply: www.findaphd.com/phds/project...
Deadline 20 Oct
#PhD #Tuberculosis #Epidemiology #InfectiousDisease

27.09.2025 07:10 โ€” ๐Ÿ‘ 5    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Policy and Research | Global TB Caucus Discover the latest tuberculosis policy briefs, research insights, and evidence-based recommendations from the Global TB Caucus. Our Policy and Research page features global TB data, legislative frame...

Nice to see the latest #GlobalTBCaucus advocacy tool. This should come in handy for evidence-based fundraising as we face challenges in global health funding.
www.globaltbcaucus.org/policy-and-r...

26.09.2025 16:18 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Our work on modelling population-wide screening in Viet Nam is now available in PLOS Global Public Health! tinyurl.com/3ymhuj5s

11.09.2025 03:54 โ€” ๐Ÿ‘ 12    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3
Differences in Tuberculosis Prevalence by Sex Over 1993-2024: A Systematic Review and Meta-Analysis Background: Tuberculosis (TB) prevalence is higher among men than women in low- and middle-income countries (LMICs). However, summary measures of sex difference

1/ Itโ€™s been 10 years (๐Ÿ˜ฎ) since we reported that #TB prevalence was twice as high in men as in women.

๐Ÿ“ข Our new preprint explores how sex differences have shifted with more recent national prevalence surveys and growing attention to #gender responsive TB prevention and care.

bit.ly/4gqP1LH

16.09.2025 11:50 โ€” ๐Ÿ‘ 8    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

Our systematic review of rural/urban differences in #TB prevalence shows evidence of rapidly urbanising epidemics in many settings, with differences across countries and regions.

Link to preprint below โฌ‡๏ธ

22.09.2025 07:55 โ€” ๐Ÿ‘ 8    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The potential impact, cost and cost-effectiveness of tuberculosis interventions - a modelling exercise Background While a range of interventions exist for tuberculosis prevention, screening, diagnosis, and treatment, their potential population impact and cost-effectiveness are seldom directly compared,...

At a time when global resources for #TB research, development, prevention, and care are limited, which interventions should be prioritised in high burden settings?

๐Ÿ“ข Our new pre-print compares the impact, cost, and cost-effectiveness of 9 TB interventions in 3 countries. 1/n

bit.ly/3V3vXth

05.09.2025 10:05 โ€” ๐Ÿ‘ 11    ๐Ÿ” 9    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Exploring trade-offs in diagnostic algorithm, population coverage, and duration of community screening for tuberculosis Background Current tuberculosis (TB) prevention and care strategies have failed to reduce disease burden at the pace required to meet global targets. Community screening may enable more rapid declines...

Community screening for #tuberculosis could extend the reach of #TB services, but evidence on its effectiveness is limited.

In our latest preprint, we examine the epidemiological impact of trade-offs in diagnostic algorithm, population coverage, and duration of screening. 1/n

bit.ly/3UK7pFD

27.08.2025 14:55 โ€” ๐Ÿ‘ 12    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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The Union's TB Undernutrition working group is hosting a webinar with Dr Matthew Saunders.

๐Ÿ“… 21 August at 2pm CET

Dr Saunders (@lshtm.bsky.socialโ€ฌ) will share findings from a new analysis that redefines the relationship between BMI and TB incidence.

๐Ÿ“ง To join email membership@theunion.org.

07.08.2025 13:22 โ€” ๐Ÿ‘ 3    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Within-country heterogeneity in patterns of social contact relevant for tuberculosis infection transmission, prevention, and care Mycobacterium tuberculosis (Mtb) transmission is driven by variable social, environmental, and biological factors, including the number and duration of indoor contacts. Social contact data can provide...

Our new study examines social contact patterns in urban, peri-urban, and rural communities and their implications for #TB interventions like household contact tracing, infection prevention, and cluster RCTs. #MedSky #EpiSky #IDsky #TBSky

Read more in @plosglobalpublichealth.org

15.07.2025 21:49 โ€” ๐Ÿ‘ 14    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The potential impact of reductions in international donor funding on tuberculosis in low-income and middle-income countries: a modelling study We estimate substantial potential impacts on tuberculosis morbidity and mortality due to reductions in international donor funding. Expanded support from domestic and international donors is essential...

Sobering study on the devastating impact of aid cuts on tuberculosis incidence and mortality in low and middle income countries

Governments of highest TB burden nations will need to wake up and invest more!

www.thelancet.com/journals/lan...

14.07.2025 10:17 โ€” ๐Ÿ‘ 61    ๐Ÿ” 37    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3

Reduced international donor funding through not only the termination of #USAID, but also announced reductions in donor pledges to #TheGlobalFund from other countries, could lead to substantial potential impacts on #TB morbidity and mortality.

Read how in our new study in @lancetgh.bsky.social ๐Ÿ‘‡

15.07.2025 12:27 โ€” ๐Ÿ‘ 7    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Figure 1. Estimated number of trial endpoints in the control group of a prevention-of-disease vaccine trial in a high disease-burden setting showing number of endpoints on the y-axis and time in months on the x-axis. For bacteriologically confirmed symptomatic tuberculosis disease endpoints only, we estimate 69 endpoints, and for combined bacteriologically confirmed asymptomatic and symptomatic tuberculosis disease endpoints, we estimate 151 endpoints. Scenario assumes symptomatic disease incidence before trial screening of 300/100โ€‰000 per year and following 10โ€‰000 individuals over 3 years. Prevalent symptomatic and asymptomatic tuberculosis disease are screened out in month 0 and are not trial endpoints. Active screening occurs every 6 months for both scenarios and participants self-presenting with symptoms suggestive of tuberculosis disease would also be investigated.

Figure 1. Estimated number of trial endpoints in the control group of a prevention-of-disease vaccine trial in a high disease-burden setting showing number of endpoints on the y-axis and time in months on the x-axis. For bacteriologically confirmed symptomatic tuberculosis disease endpoints only, we estimate 69 endpoints, and for combined bacteriologically confirmed asymptomatic and symptomatic tuberculosis disease endpoints, we estimate 151 endpoints. Scenario assumes symptomatic disease incidence before trial screening of 300/100โ€‰000 per year and following 10โ€‰000 individuals over 3 years. Prevalent symptomatic and asymptomatic tuberculosis disease are screened out in month 0 and are not trial endpoints. Active screening occurs every 6 months for both scenarios and participants self-presenting with symptoms suggestive of tuberculosis disease would also be investigated.

In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials.

doi.org/10.1016/S221...

@lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

04.07.2025 11:25 โ€” ๐Ÿ‘ 14    ๐Ÿ” 14    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

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