deprescribing.org

Cohort study published in @jamanetworkopen.com investigated 120 older US veterans who potentially experienced a Gabapentinoid-Loop Diuretic prescribing cascade.

Important findings including the downstream harms of this prescribing cascade can be found in the full article here:
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Gabapentinoid #deprescribing guidelines are being currently developed by Danijela Gnjidic's team at @sydney.edu.au. Find their project listed on our Deprescribing Guidelines Repository (DEPOT) here:
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💡 Large retrospective study finds approximately 1 in 20 nursing home residents who start #gabapentinoids go on to receive a loop diuretic within 3 months.

The study highlights the prevalence of an often overlooked prescribing cascade!

Read the full article here:
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Shared Decision Making is important when having deprescribing conversations with patients and family members who may have different perspectives.

Find helpful shared-decision making resources and patient information sheets from deprescribing.org here:
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Identifying deprescribing profiles in older adults from 14 countries using the Patient Deprescribing Typology AbstractBackground and Objectives. Categorizing older adults by their medication and deprescribing beliefs may support tailored communication and shared de

Patient's attitudes towards their medications, information-seeking behaviours, & #deprescribing preferences were studied across 14 different countries 🌍 , with 3 distinct categories of patients found.

Discover detailed insights from the full study here:
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Indigenization action plan — Do I still need this medication? Is deprescribing for you? Select \u201CAccept all\u201D to agree to our use of cookies and similar technologies to enhance your browsing experience, security, analytics and customization. Select \u201DManage cookies\u201D or…

Piqued your curiosity on the importance of indigenous reconciliation in healthcare? 🤔

Learn more about the IWG and CADeN's Action Plan for Decolonizing and Indigenizing Medication Appropriateness in Canada here:
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Great to see our Co-Director Wade Thompson's contribution to a reflective article on Supporting Medication Appropriateness Among Indigenous Peoples in Canada!

Read about the CADeN Indigenization Working Group (IWG) and their learnings in the full article here:
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Find our complementary deprescribing.org #PPI #Deprescribing Tools & Resources here:
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A Budget Impact Analysis conducted for adult patients using PPIs long-term inappropriately in England, UK 🇬🇧 found an estimated net savings of £11.5 million would be realized over a 5-year period if 20% of patients had their PPI stopped!

Read the full analysis here:
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@england.nhs.uk

Check out @wypartnership.bsky.social and @england.nhs.uk's new webpage on "Anticholinergic Medicines" and their risks below 👇

www.wypartnership.co.uk/our-prioriti...

Always great to see new resources promoting safe medication use in older adults!

Don't miss out on future updates!

E-mail deprescribing@deprescribing.org and ask to be added to our mailing list.

🎉 Our Fall 2025 Newsletter is now out! 🎉

Learn all about our updates, including new resources, publications, & more:
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A heartfelt thanks to all of our team members, partners, & collaborators that helped to spread the word of #deprescribing over the past year! 👏

Find helpful resources for #PPI #Deprescribing such as deprescribing guidelines, algorithms, patient resources, and more from deprescribing.org here:

deprescribing.org/resources/de...

The C-SENIoR Trial, recently published in the Drugs & Aging journal by @springernature.com demonstrates the outcomes of a multifaceted, multidisciplinary intervention on Proton Pump Inhibitor (PPI) #deprescribing!

Read the full article here:
link.springer.com/article/10.1...

Also check out the Opioid Deprescribing Guidelines from Aili Langford's team at the University of Sydney here:
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Find helpful shared-decision making tools & other deprescribing resources at:
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Great to see Opioid Deprescribing highlighted in @nejm.org!

Opioid deprescribing through a tailored, patient-centered plan is recommended when the potential harms of opioid therapy outweigh the potential benefits.

Link to the article here:
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@sydney.edu.au

💡 Find a link to the new resources for patients, carers, and healthcare providers, developed in collaboration between ISMP Canada, Deprescribing.org, and Canada's Drug Agency here:
www.cda-amc.ca/appropriate-...

🚨 Be sure to sign-up for the "More Medications May Not Be Better" Webinar hosted by the Canadian Medication Safety Network on Wednesday November 26 from 12 - 1 PM ET!

Join the conversation on addressing potentially inappropriate #polypharmacy.

Registration Link:
us02web.zoom.us/meeting/regi...

The talk will occur during World Antimicrobial Resistance Awareness Week (WAAW), a global campaign from November 18 to 24 to raise awareness and promote action against the spread of drug-resistant pathogens.

Learn more about WAAW here:
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Join @choosingwiselyca.bsky.social on November 18 at 1 p.m. ET for a free online webinar on "How Urine Tests Drive Antibiotic Overuse Across Health Care Sectors"!

Learn about how low-value urine testing can lead to unnecessary testing and antibiotic use.

Registration link here:
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🎉 A big thank you to all of the contributors to this valuable resource!

Find more helpful resources from the Appropriate Use Advisory Committee, such as the '5 Questions to Ask About My Multiple Medications' handout for patients here:
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deprescribing.org, Canada's Drug Agency, & ISMP Canada, are happy to have co-developed '5 Tips to Manage Polypharmacy', a new resource for clinicians to emphasize 5 crucial tips to manage #polypharmacy.

➡️ Find Links to the Full Toolkit and Shareable Handout here:
deprescribing.org/resources/5-...

Find our deprescribing.org BZRA Deprescribing Guidelines and Resources to help with the process here:
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Learn about CBTi, a free non-pharmacological alternative to sleep medications here:
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Intriguing study from @thelancet.com finds #deprescribing sleep medications in adults over age 50 could:
📉 Reduce the lifetime incidence of falls by 8.5% & cognitive impairment by 2.1%
📈 Increase life expectancy by 0.11 years
💵 Result in net lifetime savings of $6,600 per person
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💡 Learn more about Canadian Patient Safety Week (Oct 27 to 31), and how you can spread awareness here:
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🗣️ All Voices for Safer Care!

@he-es-canada.bsky.social
#CPSW2025

Don't miss out on a free webinar, "Taking multiple medications? 5 questions to ask" to be presented by @dremilymcd.bsky.social on Oct 29, 2025 at 12:00 PM ET hosted by the Canadian Medication Appropriateness and Deprescribing Network!

👉 Find the registration link here:
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A-I-D for cascades: an application of the Behaviour Change Wheel to design a theory-based intervention for addressing prescribing cascades in primary care Prescribing cascades, which occur when a medication is used to treat the side effect of another medication, are important contributors to polypharmacy. There is an absence of studies that evaluate…

❗ Be sure to also check out the team's previous publication on using the Behaviour Change Wheel (BCW) Framework to design sample interventions for addressing prescribing cascades:
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Continue to follow deprescribing.org for more exciting work on prescribing cascades!

🎉 Congrats to Sameera Toenjes and her team for an excellent publication in @plosone.org highlighting the perspectives of primary care clinicians regarding perceived barriers, facilitators, and team roles in addressing prescribing cascades:

Read the full article here!
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Why Deprescribing is as Important as Prescribing What you need to know about going off a medication

Thanks @daphneberryhill.bsky.social for showcasing deprescribing.org on the "Meet Me at the Medcart" substack!

Read the full article where Daphne and @lisamccarthy.bsky.social discuss key points to keep in mind while #deprescribing:
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Consider following the Medcart Substack! 👏 👏

Also check out:
➡️ A Playbook for Medication Optimization for Sustainability in Inpatient Care:
cascadescanada.ca/resources/me...

➡️ deprescribing.org Guidelines and Algorithms:
deprescribing.org/resources/de...

@ccghc.bsky.social
@longwoods.bsky.social