People are starving to death, or being gunned down while desperately trying to access food at aid sites β even journalists are in grave danger. This abhorrent situation cannot be allowed to continue
www.bbc.co.uk/news/live/cv...
@andytruman4.bsky.social
Group Leader at the John Innes Centre. Biosynthesis and discovery of specialised metabolites. Norwich. He/Him. https://www.jic.ac.uk/people/andrew-truman/
People are starving to death, or being gunned down while desperately trying to access food at aid sites β even journalists are in grave danger. This abhorrent situation cannot be allowed to continue
www.bbc.co.uk/news/live/cv...
Thanks for your advocacy and this excellent letter, @anthrofuentes.bsky.social !
18.07.2025 14:02 β π 19 π 12 π¬ 2 π 0Also, wasnβt particularly fast!
12.07.2025 13:16 β π 0 π 0 π¬ 0 π 0Cycling achievement unlocked: Strava βexcludingβ my ride as its rubbish AI canβt believe I could ride this fast π
12.07.2025 12:38 β π 2 π 0 π¬ 2 π 0Or why Nocardia harbour massive multi-domain proteins that may be over 50,000 AAs (5.6 MDa!) in some cases with no known function for the organism? Bigger than titin and PKZillas. Should stop this procrastination π
09.07.2025 23:03 β π 0 π 0 π¬ 0 π 0New grant application: "Ignorance is a really good reason for you to give me some funding, please"
09.07.2025 22:39 β π 0 π 0 π¬ 0 π 0It always pleases me to see how little we know. I can pick a random ~700 AA protein from a bacterial genome and it has no conserved domains and no characterised structural homologues, yet there are >1000 homologues across diverse Gram+ and Gram- bacteria.
09.07.2025 14:34 β π 6 π 0 π¬ 2 π 0Hungary banned Pride marches. This is the response βπ³οΈβπ
28.06.2025 22:54 β π 973 π 210 π¬ 10 π 4Super happy to see our work on lydiamycin biosynthesis, structure and function published in @pnas.org π
www.pnas.org/doi/10.1073/...
The work is described in the thread below, where we use BGC info to guide the discovery of multiple key features of this antibiotic.
@johninnescentre.bsky.social
Returning home after a fun couple of days in London at the RSC Chemical Biology Symposium and then the Chemical Biology Interface Council meeting. Excellent talks and always a joy to return to Burlington House @rsc.org
13.05.2025 17:13 β π 2 π 0 π¬ 0 π 0Happy Tuesday to everyone apart from whoever approved this awful design! Annoys me every time I use Greater Anglia.
13.05.2025 17:08 β π 0 π 0 π¬ 0 π 0Join us for the RSC Chemical Biology Leadership Retreat for Early Career Researchers! This is designed for researchers within 5 years of their first independent position. Bursuries are available (details in link below).
Venue: Imperial College London
Date: 10-12 Sep 2025
www.rsc.org/events/detai...
We're looking for a postdoc to join the lab to work on cell-to-cell communication via the apoplast. Candidate must be brave, as they will have to lead us (me) away from the plasmodesmata-lands we've inhabited for so long!
www.jic.ac.uk/vacancies/po...
If you have a few minutes spare in your busy schedule today, it's well worth taking time to read this article from @lewisgoodall.com.
20.02.2025 09:05 β π 65 π 14 π¬ 2 π 2PRESS RELEASE - Professor Uauy appointed as Director of the John Innes Centre
Following an international search, we are delighted to announce that Professor @cristobaluauy.bsky.social has been appointed as the next Director of the John Innes Centre.
www.jic.ac.uk/press-releas...
@ukri.org
Utterly bonkers. Iβm stating the very obvious, but itβs remarkable (yet also depressingly predictable) how quickly the proponents of βfree speechβ start banning everything they donβt like.
11.02.2025 14:49 β π 0 π 0 π¬ 0 π 0We have an exciting full-time permanent position available for a proteomics specialist for the Proteomics platform at @johninnescentre.bsky.social The platform has excellent facilities and provides essential experimental expertise research at the institute.
jobs.jic.ac.uk/Details.asp?...
#NowListening some banging tunes on.soundcloud.com/ZbMUDa61xrHo...
09.02.2025 21:31 β π 0 π 0 π¬ 0 π 0Trying to find an experiment we could actually do this evening and spotted βmake your own telephoneβ. Was looking promising until I realised we were all out of bladders π
09.02.2025 21:29 β π 0 π 0 π¬ 1 π 0Harmless Scientific Experiments for Boys (the introduction does at least acknowledge that girls can also use the book) including such βharmlessβ experiments as making gas from coal, and a DIY thermometer involving your own glass blowing and βa very small quantity of mercuryβ π€
07.02.2025 13:20 β π 2 π 0 π¬ 1 π 0Well the award for most cowardly, boot-lickingest academic society has squarely gone to the American Society of Microbiology, who has taken down features of various non-white scientists. Absolutely pathetic behavior. Those articles are now coming up as βunder reviewβ. Truly sickening cowardice here.
03.02.2025 04:39 β π 17916 π 4858 π¬ 342 π 319Is anyone having issues with NCBI at the moment? Really difficult to reliably retrieve sequence data using Entrez. Unsure if this is an impact of the absurd presidential decisions about the NIH, or just routine maintenance?
28.01.2025 15:28 β π 0 π 1 π¬ 0 π 0This is how Bruce Wayne became a millionaire
09.01.2025 11:00 β π 21 π 4 π¬ 0 π 0Very happy to share the final version of our work on the evolution of broad host virulence in Pseudomonas out now @cellhostmicrobe Itβs just in time for the holidays ππ¦ www.cell.com/cell-host-mi...
19.12.2024 16:10 β π 101 π 47 π¬ 3 π 2Congratulations! Excellent work!
19.12.2024 19:29 β π 1 π 0 π¬ 1 π 0Returning to the UK after a great trip to beautiful Gent. Alway a pleasure to hear about the natural products research happening there π Also got to dress up in a gown for the first time in years! Now to the JIC Mol Micro Xmas lunch to βrecoverβ after last nightβs Belgian beers π
13.12.2024 09:41 β π 2 π 0 π¬ 0 π 0Taking Britain out of the Erasmus+ programme was a huge mistake. Labour must rejoin and accept the EUβs offer of a youth mobility scheme
12.12.2024 09:25 β π 1584 π 456 π¬ 52 π 20Are you working on natural products? Weβve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...
10.12.2024 08:05 β π 92 π 53 π¬ 4 π 12We find a lot of proteins - particularly antibiotic biosynthetic enzymes - are produced in soluble form in Streptomyces lividans but not E.coli. Itβs a useful platform for the production of otherwise intractable proteins.
29.11.2024 16:02 β π 12 π 8 π¬ 0 π 1The Natural Products Atlas 3.0: extending the database of microbially derived natural products - thanks to the Linington lab for letting the Duncan lab be part of the curation efforts academic.oup.com/nar/advance-... #NaturalProducts #SpecializedMetabolites #microsky #microbialchemistry
26.11.2024 17:13 β π 80 π 35 π¬ 0 π 1