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Allison Williams

@allisonmck.bsky.social

Assistant Professor @ UCSF Investigator @ CZ Biohub San Francisco Williamslab: https://williamslab.ucsf.edu

95 Followers  |  121 Following  |  19 Posts  |  Joined: 17.11.2024
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Posts by Allison Williams (@allisonmck.bsky.social)

πŸ˜‚πŸΎ Happy New Year

01.01.2026 20:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It was such a fabulous visit with wonderful and engaging talks from all the speaker. This was also student organized which made it so much more special.

18.09.2025 21:05 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

So happy for you!

19.06.2025 20:47 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Congratulations Natasha!

19.06.2025 19:52 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Beautiful

03.04.2025 03:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

The profanity police is looking for some attention! I can also share some choice Jamaican and French words to give their account some traction!

06.03.2025 23:09 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Phosphorylation State Dictates Bacterial Stressosome Assembly and Function https://www.biorxiv.org/content/10.1101/2025.03.04.640944v1

06.03.2025 14:34 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Thank you twin!:). It was a labor of love and persistence.

06.03.2025 17:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Also thank you chatGPT for helping to shorten my post to fit word limit restrictions here :)

06.03.2025 07:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Phosphorylation State Dictates Bacterial Stressosome Assembly and Function Bacterial pathogens rely on their ability to sense and respond to environmental stressors to survive and maintain virulence. The stressosome, a 1.8-megadalton nanomachine, serves as a critical sensor ...

πŸŽ‰ Huge thanks to our incredible team, collaborators, and supporters! πŸŽ‰
Thanks to the powerful imaging capabilities @ UCSF!
Grateful to the NIH and CZ Biohub for making this research possible!
www.biorxiv.org/content/10.1...
#StructuralBiology #CryoEM #Microbiology #Phosphorylation #NIH #CZBiohub

06.03.2025 07:38 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Phosphorylation State Dictates Bacterial Stressosome Assembly and Function Bacterial pathogens rely on their ability to sense and respond to environmental stressors to survive and maintain virulence. The stressosome, a 1.8-megadalton nanomachine, serves as a critical sensor ...

🚨New preprint!🚨 How do bacteria sense stress and activate survival pathways? We solved multiple cryo-EM structures of Listeria stressosomes in different phosphorylation states, revealing how phosphorylation fine-tunes stress responses and virulence. πŸ¦ πŸ”¬
πŸ“„ Read more: www.biorxiv.org/content/10.1...

06.03.2025 07:22 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Phosphorylation State Dictates Bacterial Stressosome Assembly and Function Bacterial pathogens rely on their ability to sense and respond to environmental stressors to survive and maintain virulence. The stressosome, a 1.8-megadalton nanomachine, serves as a critical sensor ...

Phosphorylation is the switch that controls bacterial stressosomes! Our cryo-EM study shows how stepwise phosphorylation activates Listeria stressosomes to trigger survival pathways. A finely tuned mechanismβ€”reminiscent of eukaryotic signalosomes! 🦠⚑
πŸ“’ Check it out: www.biorxiv.org/content/10.1...

06.03.2025 07:20 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Phosphorylation State Dictates Bacterial Stressosome Assembly and Function Bacterial pathogens rely on their ability to sense and respond to environmental stressors to survive and maintain virulence. The stressosome, a 1.8-megadalton nanomachine, serves as a critical sensor ...

Bacteria adapt to stress using massive nanomachines! πŸ› οΈπŸ¦  Our new work reveals how phosphorylation controls the Listeria stressosome, linking structural changes to survival and virulence. A bacterial signaling hub with striking parallels to eukaryotic inflammasomes!
www.biorxiv.org/content/10.1...

06.03.2025 07:19 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
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James Harrison, whose blood donations saved over 2 million babies, has died Harrison, whose plasma contained a rare antibody, rolled up his sleeve 1,173 times from 1954 to 2018. The Australian is credited with helping 2.4 million babies and advancing scientific research.

A good man has left this world. May he be remembered, because his life was a blessing.

04.03.2025 02:15 β€” πŸ‘ 300    πŸ” 73    πŸ’¬ 6    πŸ“Œ 8
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The world’s platform for change Change.org is the world’s largest petition platform, using technology to empower more than 200 million users to create the change they want to see.

Do you want the NIH, policymakers and lawmakers to
reverse the cap on how we invest in American science infrastructure? Consider joining me in signing this petition: chng.it/kK2HMP5pGk

02.03.2025 16:27 β€” πŸ‘ 5    πŸ” 5    πŸ’¬ 2    πŸ“Œ 0

Monday: Never gave you up
Tuesday: Never let you down
Wednesday: Never ran around and deserted you
Thursday: Never made you cry
Friday: Never said goodbye
Saturday: Never told a lie and hurt you

(Dedicated to all the fantastic colleagues at NIH, NSF, and CDC)

24.02.2025 14:23 β€” πŸ‘ 142    πŸ” 21    πŸ’¬ 1    πŸ“Œ 0

Speaking of healthcare. Let's make @bsky.app the platform that fights misinformation. Some great follows are @drsusanoliver.bsky.social @jsm2334.bsky.social @therealtruther.bsky.social

Let's get them more followers and engagement than other platforms and let health science accounts find a home

25.01.2025 17:55 β€” πŸ‘ 75302    πŸ” 14172    πŸ’¬ 3679    πŸ“Œ 682


β€œThere comes a time when one must take a position that is neither safe, nor politic, nor popular, but he must take it because conscience tells him it is right.”
– Martin Luther King Jr.
My ancestors knew that the hardest choices are the most necessary. #Courage #Integrity #Conscience

18.01.2025 18:21 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

It’s a good stand-in…bravo! It also happens to be one of my favorite dishes. Well done.

08.01.2025 18:56 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Did anyone else in San Francisco think they misread the tornado emergency alert at 6:15 AM this morning? Last week it was a tsunami warning, and now a tornadoβ€”yikes!

14.12.2024 17:50 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Dietary fructose enhances tumour growth indirectly via interorgan lipid transfer - Nature Dietary fructose enhances tumour growth in animal models of melanoma, breast cancer and cervical cancer indirectly via metabolite transfer.

Liver metabolizes high fructose corn syrup to fructose, which leads to increase production of LPC lipids that promote tumor growth.

#Glycotime

www.nature.com/articles/s41...

11.12.2024 08:42 β€” πŸ‘ 72    πŸ” 18    πŸ’¬ 1    πŸ“Œ 1
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The restoration of the Notre Dame Cathedral is a nice reminder that catastrophes do not last forever, and what's broken can also be fixed.

07.12.2024 03:55 β€” πŸ‘ 476    πŸ” 60    πŸ’¬ 17    πŸ“Œ 6
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Exciting times in the Williams lab! Big congratulations to Javarcia for successfully passing his qualifying exam! πŸŽ‰πŸ‘ #MSTP Journey #TeamScience #UCSF!

07.12.2024 05:46 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Amazing

04.12.2024 08:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you. Right back at you

25.11.2024 07:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

β€œThrilled to join Bluesky! My social media hiatus has come to an end. Looking forward to collaborating, exploring, laughing and celebrating with my amazing colleagues. 🌟 #NewBeginnings #TeamScience #BlueSkyThinking

17.11.2024 01:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0