NIK-OI 🦬

At some point a civil society is unequipped to deal with bad actors and sociopaths that stay somehow within the bounds of legality and are immune to ridicule

🚨Join us! We're soon opening 3 postdoctoral positions in #AIDrivenBiology. Seeking biologists (especially microbiology and infection biology), computer scientists, and microscopy developers. Ideal candidates are those eager to use or develop next-gen tech for cell biology. Get in touch (DM/email)

Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @mbisg.bsky.social, and the Dept of Physiology at @nusingapore.bsky.social in the fall! More about our work on vascular mechanobiology in health & disease mechano-medicine-lab.com

🔬 @christlet.bsky.social, @henriqueslab.bsky.social, and colleagues introduce the Structural Repetition Detector (SreD), an unsupervised approach for identifying repetitive biological structures in #Fluorescence #Microscopy data.

🔗 Click to check it out: go.nature.com/44g9fDG

#Microscope #Imaging

This is why we love #cellmigration

#Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis.

I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock !

#scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬

Come and Join our Dpt in Beautiful #Geneva !

We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.

Giant map details nerves across a mouse's body: see stunning pics High-resolution imaging method could lead to wiring diagram for the whole body.

Using a custom microscope, researchers mapped the entire peripheral nervous system of a mouse at micrometer resolution in 40 hours. The method reveals nerve paths from brain to organs and could help build full-body connectomes in other species.
🧪🐀🧠
#Neurotech
#Microscopy
#Neuroanatomy
#Biology

🖼️ Image from @moffittnews.bsky.social shows a patient-derived xenograft model of ovarian cancer.

🔬 Imaging was performed using a Nikon AX R #Confocal #Microscope system. Cell nuclei are in blue, epithelial cells in green (EpCAM), infiltrating T cells in red (CD4), and actin in magenta.

#Microscopy

Two glowing yellow and red rings (the black holes) against a black background and separated down the middle by a thin white line. The left black hole has a blue circle and white elliptical shape overlaid. The right black hole has just the elliptical overlaid, with white lines to show how the black hole aligns with the shape.

Imagine a donut...now squash it🍩. That's what the black hole inside M87* looks like!

New EHT research reveals that the squishy distortion is not due to gravity, but the turbulent, swirling plasma around the black hole: www.aanda.org/10.1051/0004... #space #blackhole #astronomy #astrophysics

Isotropic STED resolution (~70 nm) with a single objective using a new type of light modulator. "m-order vortex retarder" sounds like a Star Trek contraption but the images are stunning! arxiv.org/abs/2507.06718

Happy Independence Day South Sudan! Youngest country in the world, may we one day know peace ❤️❤️

Triglycerides are an important fuel reserve for synapse function in the brain - Nature Metabolism Kumar et al. show that under glucose-depleted conditions, neurons can use fatty acids as an alternative source of energy to support synaptic function.

Well what do you know!? This might be the most interesting unorthodox orthodox metabolism paper this year.

He sat on the edge of the hollow purring while she hooed from a nearby tree. Its almost certainly too late in the season for them to breed, but they are clearly strongly bonded already, and hopefully next year they will nest together 4/4
#brisbane #birds #wildoz

The newly paired male Powerful Owl asleep at sunset yesterday. The female was on a branch about 10m away 1/4
#brisbane #birds #wildoz

Another Journal Club article from @preprintclub.bsky.social -
Mehdi Chaib and James Allison @mdanderson.bsky.social report on @biorxiv-immuno.bsky.social preprint by Han et al. that describes a mechanism by which metastatic tumours secure iron in the bone marrow
#immunosky #cancersky
rdcu.be/euBTD

It was a huge pleasure to write this spotlight commentary together with @inflammasomelab.bsky.social and @JaredCoombs on the recent Cell paper of Xingbin Hu lab on spectosis in red blood cells! Congrats to all the authors for their novel and elegant study in discovery miniNLRP3 signaling in RBC 👇

It was a great pleasure having you with us Daniel and thank you for sharing your amazing work on myddosome! ☺️🤩

A practical look at cryo-electron tomography image processing: Key considerations for new biological discoveries Cryo-electron tomography (cryo-ET) enables 3D visualization of complex biological environments without the need for purification, thereby preserving t…

Happy to say that my Current Opinion in Structural Biology article came out today. I hope it helps to guide to you in using cryo-ET to make new biological discoveries!

www.sciencedirect.com/science/arti...

BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.

U.S. measles cases reach 33-year record high as outbreaks spread Johns Hopkins University data reflects the public health reversal in defeating the vaccine-preventable disease since measles was officially eliminated from the U.S. in 2000.

The United States has recorded its highest annual measles cases in 33 years. The milestone marks a public health reversal in defeating a highly contagious, vaccine-preventable disease as the anti-vaccine movement gains strength.

🚨 #ExM meets #eSRRF 🔬🏄🌊 the full protocol now in ‪@natprot.nature.com‬: doi.org/10.1038/s415...

Today is June 25. On this date in 1903 Marie Curie defended her doctoral thesis on radioactive substances at Université de la Sorbonne in Paris, becoming 1st woman in France to receive a doctoral degree. Image shows the thesis cover.

hanging out with strangers in a campus pub should be considered part of the serious process of thinking

🧐 How can I make sure my sample expands properly and how do I find the right eSRRF processing parameters?
Here you will find all the nitty-gritty details on #ExM sample preparation, 🔬 & #eSRRF processing 🏄, common pitfalls 🪨 and troubleshooting advice🛠️.

🔬👨‍💻📰 #SReD is out!
Automated structural detection for #ImageJ & #FIJI, from nano to macro ✨🐘. No training data, no bias - texture analysis with GPU acceleration!⚡️
Brainchild of @afonsomendes92.bsky.social and adventure w @christlet.bsky.social lab + friends.

Check: www.nature.com/articles/s41...

Our researcher @afonsomendes92.bsky.social & collaborator @christlet.bsky.social just published on @natcomms.nature.com.🙌 They developed a new analysis tool that automatically finds repeating patterns in structures in biological images without prior knowledge.
Read it at: nature.com/articles/s41...

It's here! ✨
The #ExSRRF protocol paper is out 😍. Full details for merging Expansion Microscopy with our eSRRF analysis. From cells to tissue. A partnership with @puellesv.bsky.social's lab. Lead by Dominik Kylies and @hannah-superres.bsky.social + colleagues. #ExM #eSRRF
➡️ Open link: rdcu.be/euvEw

I am beyond excited to share our new preprint ‘A neural basis for distinguishing between imagination and reality’ with Thomas von Rein, @peterkok.bsky.social and @smfleming.bsky.social! osf.io/preprints/ps... a thread 🧵

How the brain separates real images from those it imagines Neuroscientists have found the regions that keep them apart.

Cool article about our recent paper by @nature.com 🤩 @peterkok.bsky.social, @smfleming.bsky.social www.nature.com/articles/d41...

My latest Aronov lab paper is now published @Nature!

When a chickadee looks at a distant location, the same place cells activate as if it were actually there 👁️

The hippocampus encodes where the bird is looking, AND what it expects to see next -- enabling spatial reasoning from afar

bit.ly/3HvWSum