Shefali

nice hack i've done twice this year...drop by CSHL for a day (Neurofly), listen bunch of talks and chat up posters, see ~20 people (inc 2 collaborators IRL for 1st time, and our former star grad student Piero Sanfilippo), share updates on #FlyBase with community and urge donations, and back home! 🪰

a little girl wearing sunglasses and a blue dress is dancing in a hallway . ALT: a little girl wearing sunglasses and a blue dress is dancing in a hallway .

Because it's not a working day tomorrow !
#Fallbreak

It's officially wear jacket in the morning and carry it in the afternoon season!
#midwest

FlyBase Homepage FlyBase: a database for drosophila genetics and molecular biology

Searches and tools are currently down for FlyBase.org. Our developers are working on getting us back up.

Everyone go out and look at the moon 🌝
It is beautiful 😍
#moon #night

Waking up to #fall weather 🍁🍂

A marine iguana on a rock, in front of blue and white waves.

Marine iguanas have lower metabolic rates during El Niño

This article, by Shahar Dubiner and colleagues, is Journal of Experimental Biology's Editor's choice for the month.

Find out more: journals.biologists.com/jeb/article/...

#MarineIguana #Iguana #MarineLife #Research #Animals #SeaLife

A short photoperiod alters brain metabolism and cold resistance in Drosophila melanogaster
#Drosophila

Feel so validated !
☕☺️ ✅
#phdlife #coffee #community

When prism decides to update itself in the middle of my analysis 🤷🏽‍♀️🤦🏽‍♀️🙄
#phdlife

In a surprising turn of events, I now have a graduate student 🤗

I want to do this right. So I’m soliciting advice from the wise & experienced 😅 - what are your best tips for being a good advisor/PI/graduate student mentor? ✨

Amazing paper on how metabolites act as signaling factors which impact growth and development by ways which are not limited to merely changes in flux, energy production and biogenesis.
#Drosophila #metabolism #ecdysone #Ampk #interorgancommunication

A study in #G3journal examines the interplay between ecdysone signaling and O-GlcNAcylation in #Drosophila intestinal stem cell proliferation and gut homeostasis in aging, thereby linking age-related, abnormal stem cell proliferation to metabolic diseases. buff.ly/cBkR5tY

📅 Oct 29, 1 p.m. EDT
Postdoc Opportunities Abroad
Hear from early career researchers building successful careers outside the U.S.—and get tips for planning your own path. @ethanewe.bsky.social

You’ll need to create a GSA account, but both events are free—register now: buff.ly/DUzRI4Y

2/2🧵

🚨 Two upcoming GSA panels highlight international research opportunities for early career scientists!

📅 Oct 20, 11 a.m. EDT
Grants and Funding in Europe
Learn how to secure funding abroad with insights from the @erc.europa.eu + The Research Bid.

@limor-zwi-dantsis.bsky.social

1/2🧵

We are very pleased to announce our joint meeting with the German @gfeev.bsky.social and the Dutch Developmental Biology Societies, which will take place in Potsdam from the 10-13th of March 2026. Registration is now open! www.uni-potsdam.de/en/gfe-meeti...

A GPCR signaling pathway in insect odor detection Odor detection differs fundamentally in vertebrates, which use G protein-coupled receptors (GPCRs), and insects, which employ ion channels. Here, we report the first evidence for a GPCR defining tunin...

Having personally sworn for years that insects don’t use GPCRs for odour detection, Suguru Takagi (@sugurutakagi.bsky.social) discovers that, in fact, they sometimes do …

www.biorxiv.org/content/10.1...

Medicine Nobel goes to three researchers who identified immune system’s security guards Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease

This year’s #NobelPrize in Physiology or Medicine has been awarded to three scientists for discovering how the immune system distinguishes friend from foe. https://scim.ag/3Wt5rdi

Maa sending me pictures of my namesake flowers this morning (India time morning) !

‘Cities under the sea’ Nanotechnology offers a way to restore and re-create coral reef biodiversity.

When Jennifer Matthews first saw corals while learning to scuba dive, she was mesmerized by their neon yellows, pinks and blues.

🪸 “They were so beautiful,” she recalled.

Read more about Matthews’ journey from that moment of wonder to a career studying #coral resilience: ow.ly/vqhZ50X6OHA.

Male CNS Connectome A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

Into the world of greens before the fall kicks in !
#blueheron #birds #bees #butterfly #browncounty #photography

Totally agreeee on that 🙌🏽

#Bollywood movie night !
Amar Akbar Anthony 🍿🎬📺
#manmohandesai

To Come Home To Yourself May all that is unforgiven in you Be released. May your fears yield Their deepest tranquilities. May all that is unlived in you Blossom into a future Graced with love.

Friend gave me a John O’Donohue book recently. It’s quite good.

“To Come Home To Yourself”

Remote control of AMPK via extracellular adenosine controls tissue growth - Nature Cell Biology Zhang et al. demonstrate that AMPK can be activated by signalling metabolite, adenosine, under non-stress conditions during Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.

💫NEW: @telemanlab.bsky.social & co demonstrate that #AMPK can be activated by signaling metabolite, #adenosine, under non-stress conditions during #Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.
bit.ly/4gX6njF

This 👇🏽👇🏽👇🏽

How the Brain Balances Excitation and Inhibition | Quanta Magazine A healthy brain maintains a harmony of neurons that excite or inhibit other neurons, but the lines between different types of cells are blurrier than researchers once thought.

As we age, the delicate equilibrium of our billions of neurons can teeter — sometimes with serious cognitive consequences. But new research into neuronal regulators is helping us better understand how to re-level things once the scale has been tipped.
www.quantamagazine.org/how-the-brai...

Country diary: Ragged butterflies, comatose bees – these are the last of the summer sights | Phil Gates Blanchland, Northumberland: Today’s perfect autumn day captures the dying embers of a memorable summer

Country diary: Ragged butterflies, comatose bees – these are the last of the summer sights | Phil Gates

Couldn't have asked for a better beginning of the weekend ! "Marriage of Fiagro" is definitely one of the masterpieces of operatic comedy and among the best of #Mozart 😍😊

#iubloomington #jacobschoolofmusic #opera #friday