Tyler Starr

Junior, Assistant, or Associate Specialist – Xue Lab University of California, Irvine is hiring. Apply now!

The Xue lab at UC Irvine is looking for a staff scientist to support our work investigating how microbes interact and evolve in the gut microbiome! Open to a wide range of previous experience levels, see ad for more.
recruit.ap.uci.edu/JPF09601

Virologist and HIV expert Dr. Michael Emerman retires During his 36-year career at Fred Hutch Cancer Center, Michael Emerman, PhD, made fundamental discoveries about HIV, the retrovirus that causes AIDS. He co-founded the field of paleovirology and consi...

www.fredhutch.org/content/www/...

The 2025 Bat Infectious Disease meeting is now on. Looking forward to several excellent talks, along with talks by Rita and Victoria from my lab. #BatID
Thanks to Dr. Cara Brook and her lab for organizing and hosting us!

Replaying germinal center evolution on a quantified affinity landscape Darwinian evolution of immunoglobulin genes within germinal centers (GC) underlies the progressive increase in antibody affinity following antigen exposure. Whereas the mechanics of how competition be...

Wanted to highlight our latest preprint--a huge effort by multiple people and labs, but led primarily by @wsdewitt.github.io, Tatsuya Araki, and Ashni Vora, in a very close wet-dry collaboration with @matsen.bsky.social’s lab at the Hutch

www.biorxiv.org/content/10.1...

cc: @owenouyang.bsky.social @juliofierro.bsky.social @jpflores.rbind.io and other bluesky-less friends :)

9 Graduate Student "Rising Stars" smiling in a group photo at the end of a successful symposium

Had a blast listening to exciting science and stories at last week's 4th annual Graduate Student Rising Stars symposium @uofubiochem.bsky.social, topped off by a keynote describing the wonders of cone snail venoms from Toto Olivera. Thanks to all of our visitors and speakers!

Phylogeny-driven design of broadly protective sarbecovirus receptor-binding domain nanoparticle vaccines Vaccines against emerging SARS-CoV-2 variants and sarbecoviruses with pandemic potential must elicit a robust humoral immune response in a population imprinted with the SARS-CoV-2 spike (S) protein. H...

Delighted to share our most recent work on designing broadly protective sarbecovirus vaccines and defining the path forward for other coronaviruses.

Led by @aminaddetia.bsky.social

@hhmi.org

www.biorxiv.org/content/10.1...

We will be welcoming nine talented Graduate Student Rising Stars to share their research with us on Monday May 19th, starting at 9:30am in HSEB 1730. The symposium will be followed by the Pace Keynote talk by Dr. Toto Olivera at 4pm!

I only joined a month or two ago! and haven’t been posting much though have been enjoying my timeline here, cleanse from twitter 😂

N:G215C virions are enlarged and show over-incorporation of N protein. Vero-TMPRSS2 cells were infected with WT (left) or N:G215C (right) viruses at an MOI of 0.1. The following day cells were prepared for electron microscopy by high-pressure freezing and freeze-substitution, then sectioned and imaged by dual-axis electron tomography. Virus-containing exit compartments were located in both samples, and virions that had completely separated from cellular membranes were selected and analyzed in 3D in order to determine the structure of intact virions and the arrangement of internal ribonucleoprotein complexes.

Non-spike protein mutations in #SARSCoV2, likely to impact viral properties, are understudied. @brucelab.bsky.social show that a #nucleocapsid protein mutation in Delta variant enhances viral growth in vitro & in vivo by increasing viral genome #encapsidation @plosbiology.org 🧪 plos.io/4iBYsaI

Booker sets a record and then starts talking about funding for postdocs and grad students ♥️♥️♥️

Saying ‘pandemic is over,’ NIH institute starts cutting COVID-19 research Grant terminations halt research on improving vaccinations and preventing future pandemics

Exclusive: Science has learned that grant termination letters went out last night to principal investigators of 29 awards made by NIAID, including nine grants that were part of a program hoping to deliver antiviral drugs to prevent future pandemics. scim.ag/4iVm7mY

first post in the good place -- had a blast on Monday at our first Starr lab ski day!