Rasmus Siersbaek

Nucleosome fibre topology guides transcription factor binding to enhancers www.nature.com/articles/s41...
▶️motif recognition on mononucleosomes affects only an individual TF binding
▶️When bound together, TFs act cooperatively or competitively to target nucleosome arrays with defined 3D organization

18.12.2024 18:53 — 👍 29    🔁 9    💬 0    📌 0

Extremely grateful to @carlsbergfondet.dk for supporting our research on #MYC in #cancer with a Semper Ardens Accelerate grant🙌🏻😄 I cannot wait to get started!! 😄😄

17.12.2024 19:00 — 👍 6    🔁 1    💬 0    📌 0

Postdoc Positions in Translational Cancer Research Application deadline: 30 November 2024 at 23.59 hours local Danish time.

📢 Looking for a #postdoc position in the intersection of #cancer, #chromatin and #epigenetics??? Still a few days left to apply to our lab in wonderful Denmark as part of the new translational cancer hub initiative🇩🇰🧪👇🏻

28.11.2024 18:20 — 👍 8    🔁 1    💬 0    📌 0

ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...

First post @bsky.app 😄😄 wanted to highlight this very innovative tech to investigate #chromatin binding! Congrats to @mitchguttman.bsky.social and the whole team👏🏻👏🏻
www.nature.com/articles/s41...

27.11.2024 18:56 — 👍 5    🔁 0    💬 1    📌 0

Three must read papers for PhD students. #scisky #PhD #science #research #academicsky

1. The importance of stupidity in scientific research

Open Access
journals.biologists.com/jcs/article/...

24.11.2024 13:54 — 👍 1223    🔁 460    💬 57    📌 82