Centre for Cancer Genetic Epidemiology

This research, published in the @thelancet.bsky.social Oncology, was led by Hend Hassan, a PhD student at the Centre for @ccge-cambridge.bsky.social @dphpc.bsky.social.

Read more: crukcambridgecentre.org.uk/news/removin...

📢 New publication from the group in @thelancetoncol.bsky.social led by Hend Hasan for her PhD, we used linked EHR + genetic testing data to study 3,400+ BRCA1/2 carriers with history of breast cancer. What happens long-term after BSO?

📄 Paper: www.thelancet.com/journals/lan...
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The contribution of coding variants to the heritability of multiple cancer types using UK Biobank whole-exome sequencing data We developed a method to estimate the contribution of rare coding variants to cancer heritability and applied it to 11 cancers in the UK Biobank. Our results provide insights into the contribution of ...

CCGE researchers evaluate the contribution of gene variants to cancer risk for multiple cancer types. The results highlight several potential new susceptibility genes including the DNA repair gene NHEJ1. Follow the link below to find out more
www.cell.com/ajhg/fulltex...

British Council Cyprus UK alumni award for Dr Kyriaki Michailidou

Congratulations on winning the British Council's Alumni Awards 2025 for Science and Sustainability
www.britishcouncil.com.cy/study-uk/alu...

📣 Job Opportunities - Alongside our recently advertised Senior Research Programme Manager position, we now have 2 more exciting opportunities to join the Cancer Data-Driven Detection (CD3) programme

1️⃣ Research Programme Manager
shorturl.at/Cs1kg

2️⃣ Research Community Coordinator
shorturl.at/4w9Na

📣CanRisk v.3 for breast and ovarian cancer risk prediction released today

www.canrisk.org

Includes

1️⃣ Adaptations to the U.K. ethnically diverse population:

Pre-print: doi.org/10.1101/2025...

2️⃣ Continuous measures of mammographic density:

Pre-print: doi.org/10.1101/2025...

Read more about our recent collaborative work on multimodal dynamic risk modelling for colorectal cancer from the talented Sam Ip and Hannah Harrison. 👇

Genetics, primary care records and lifestyle factors for short-term dynamic risk prediction of colorectal cancer: prospective study of asymptomatic and symptomatic UK Biobank participants Objectives To quantify the contributions of polygenic scores, primary care records (presenting symptoms, medical history and common blood tests) and lifestyle factors, for short-term risk prediction o...

Great to see our study looking at the contributions of different data types to short-term risk prediction for colorectal cancer diagnosis published bmjoncology.bmj.com/content/4/1/...

Key finding: primary care records (especially common blood tests) and genetics make a substantial contribution.

📣 Exciting new opportunity to join the Cancer Data-Driven Detection (CD3) program as Senior Research Programme Manager based at @dphpc.bsky.social @cambridgeuni.bsky.social

Closing date 16 March 2025

Please repost!

More about CD3 below. 👇

www.jobs.cam.ac.uk/job/50376/

Hello BlueSky colleagues – this is the new official account of the Centre for Cancer Genetic Epidemiology!

Please follow us for updates and news related to our research.

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