Dylan Burnette

Membrane blebs on a cancer cell videoed through a DIC microscope. What are blebs? Intracellular pressure within the cell blowing up tiny balloons using the plasma membrane. Or something like that. #CellBiology

This video shows an iPSC-derived cardiac myocyte videoed by Burnette Lab graduate student Emma Koory. Muscle myosin II is shown. #CellBiology

Grant reviewers hate the uncertainty that word implies; "What if they just take a bunch of videos with their microscopes?" Well, we would do that....... and some other stuff...... the idea that we would not discover something new along the way is laughable. The "other stuff" would be pretty cool.

Could we use these rare cells to uncover mechanisms underlying arrhythmias? Probably, but the way the Burnette Lab would approach that would require a lot of description-- I apologize for using such filthy language. Description indeed......

iPS cell-derived cardiac myocytes (heart muscle cells) typically beat about once per second, so I usually speed up the movies I post; otherwise, scrollers might miss the action. But every now and then, a cell looks like this in real time. #CellBiology

Beating iPSC-derived heart muscle cells videoed through a microscope. Alpha-actinin-2 is shown. #CellBiology

An iPSC-derived heart muscle cell assembling sarcomeres videoed through a spinning disk confocal microscope by Burnette Lab graduate student, Emma Koory. Alpha-actinin-2 is shown. Colors denote Z slices (red-bottom; green-middle; blue-top). Movie length- 40 hours.

Yep! Too much laser!

An iPSC heart muscle cell forming sarcomeres videoed through a microscope by Emma Koory for 20 h before it dies most dramatically. This was our first try on a new microscope, and Emma now has the imaging parameters dialed in so her cells do not go POP! Alpha-actinin-2 is shown. #CellBiology

Dylan Burnette (10th) @mag2art.bsky.social

An iPSC-cardiac myocyte (heart muscle cell) in cell culture photographed through a microscope by former Burnette lab graduate student, Dr. James Hayes. We are preparing cover submissions for his last two first author papers from the lab! Actin filaments are shown. #CellBiology

This is an iPSC-cardiac myocyte, and they can still beat during mitosis. Does this happen in vivo or is it just a cell culture thing? I do not know.

Do sarcomeres disassemble when a cardiac myocyte (heart muscle cell) enters mitosis as the literature suggests? Not completely. Here is a cardiac myocyte in metaphase. There are plenty of stacks of myosin II filaments (the core of each sarcomere) hanging about. #CellBiology

How most people think DNA is organized in the nucleus vs. how it’s actually organized. Structured illumination microscopy (SIM). Z sections shown from bottom to top of the nucleus. #CellBiology

The Burnette Lab did well this year in the Nikon Small World contest! Way to go James and Zach! 🔬
www.nikonsmallworld.com/galleries/20...

Cardiac myocytes (heart muscle cells) differentiating from iPS cells photographed through a microscope. Actin filaments and nuclei are shown. #CellBiology

Fish keratocytes isolated from a fish scale crawling around. Technique: DIC microscopy. #CellBiology.
Another #NikonSmallWorldReject

Scam site or not, it is stealing my intellectual property. It is not OK to take people's art (no matter how that art is generated) and sell it.

An iPSC cardiac myocyte (heart muscle cell) photographed through a microscope. That yellow thing is the DNA in the nucleus. The cyan things are the motor domains of myosin II, the molecular motor that drives muscle contraction. #CellBiology

Just some normal ole’ cell biology 🎨🔬
Featuring the nucleus, mitochondria, and actin.
#SciArt #CellBiology

Famous artists meet cell biology 🎨🔬
Cells reimagined through iconic styles.
The nucleus, mitochondria, and ER are shown.
#SciArt #CellBiology #AIArt #DALLE

Famous artists meet cell biology 🎨🔬
Cells reimagined through iconic styles.
The nucleus, mitochondria, and ER are shown.
#SciArt #CellBiology #AIArt #DALLE

Cubist Cell — where biology meets Picasso.
A nucleus, mitochondria, and ER reimagined through fractured planes and bold geometry.
#CellBiology

Breaking News: Emma Koory won the Best Graduate Student Talk Award at the Program in Developmental Biology retreat today! Carries on Burnette Lab tradition! #CellBiology @vubasicsciences.bsky.social

DNA in the nuclei of cells within a bee's brain photographed through a spinning disk confocal microscope. #CellBiology

Mitochondria Women's Relaxed T-Shirt T-shirt featuring mitochondria within a cell photographed through a microscope. Colors show relative Z position. This just might be the softest and most comfortable women's t-shirt you'll ever own. Co...

Someone made the decision to buy a mitochondria T-shirt this week! Yay! Its a good one! #CellBiology
mag2art.com/products/mit...

A thin section through the body wall of a mouse embryo photographed through a DIC microscope. I color-coded different tissues based on cellular morphology. The three gold circles are developing ribs. The yellow part at the very bottom is a lung. @CellBiology

I have found my spirit animal. #CellBiology

Blebbisomes! They do more than in this paper! More coming soon! #CellBiology
www.nature.com/articles/s41...

A cell with lots of membrane blebs videoed through a DIC microscope. #CellBiology