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ToGuLab

@togulab.bsky.social

Natural product lab located at HIPS Saarbrücken. Biosynthesis, Synthetic Biology, Biocatalysis and more… (@techbiodd at X)

1,354 Followers  |  317 Following  |  5 Posts  |  Joined: 08.09.2023  |  1.4958

Latest posts by togulab.bsky.social on Bluesky

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Today we had very special visitors: a TV-team from KBS (Korean Broadcasting System) was at HIPS. Tobias Gulder gave an Interview and shared insights to our work. We appreciate the interest and the possibility to show our research this way and are excited to see the result at the end of October!

25.09.2025 15:09 — 👍 4    🔁 0    💬 0    📌 0
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Expanding Polycyclic Tetramate Macrolactam (PoTeM) Core Structure Diversity by Chemo‐Enzymatic Synthesis and Bioengineering Polycyclic tetramate macrolactams (PoTeMs) derive from ornithine-based lysobacterene A. To expand the PoTeM core structure carbon skeleton by a CH2-unit, a synthetic access to lysobacterene A and an ...

The year started with Sebastian’s paper on the substrate promiscuity of the cyclization enzymes IkaBC. The paper includes chemical synthesis combined with exciting chemo-enzymatic transformations generating a plug-and-play system for PoTeMs. Check it out!
onlinelibrary.wiley.com/doi/10.1002/...

24.09.2025 08:34 — 👍 2    🔁 1    💬 0    📌 0
The Gulder group at the Castle of Saarbrücken.

The Gulder group at the Castle of Saarbrücken.

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The Gulder group has started its work at HIPS Saarbrücken! Since 01. August the full group is here and working in the old HIPS building as our new building is still under construction. In the coming weeks we will update you on what has happened throughout 2025 regarding our research! Stay tuned

17.09.2025 07:51 — 👍 7    🔁 0    💬 0    📌 0
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Chemie trifft Biologie: Zugang zu neuen Naturstoffen Team um den neuen HIPS-Abteilungsleiter Tobias Gulder entwickelt innovative Synthesestrategien für vielversprechende Naturstoffe

#Naturstoffe decken ein breites Spektrum biologischer Aktivitäten ab, sind aber aufwendig herzustellen. Ein Team um @togulab.bsky.social @helmholtzhips.bsky.social zeigt in drei Publikationen neue innovative Synthesestrategien für vielversprechende Naturstoffe.
www.helmholtz-hzi.de/media-center...

12.05.2025 12:28 — 👍 1    🔁 1    💬 0    📌 0
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Unraveling the molecular basis of substrate specificity and halogen activation in vanadium-dependent haloperoxidases - Nature Communications Vanadium-dependent haloperoxidases (VHPOs) are versatile enzymes that catalyze oxidation of halides followed by halogenation of electron-rich substrates, but the factors dictating substrate and haloge...

What is responsible for the halogen specificity & is there a Substrate binding Site in #VHPOs? Learn more about this amazing enzyme class in our latest paper @naturecomms.bsky.social Congratulations to the Team! www.nature.com/articles/s41...

02.03.2025 20:34 — 👍 7    🔁 1    💬 0    📌 0

Hi Kate - would be great to get included :-)

20.11.2024 20:03 — 👍 1    🔁 0    💬 2    📌 0

Fingers crossed - good luck!

08.09.2023 19:43 — 👍 1    🔁 0    💬 0    📌 0

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