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Globisch lab

@globischlab.bsky.social

Laboratory of Professor Daniel Globisch: Chemical Biology, Metabolomics, Organic Chemistry and Microbiota-Human Host co-metabolism for Biomarker Discovery Lab homepage: globischlab.org

867 Followers  |  458 Following  |  13 Posts  |  Joined: 16.11.2024  |  2.0682

Latest posts by globischlab.bsky.social on Bluesky

Approaches to early cancer diagnosis and the impact of artificial intelligence in oncology | Webinar
YouTube video by PANCAID Approaches to early cancer diagnosis and the impact of artificial intelligence in oncology | Webinar

How is #AI transforming early cancer detection?
Experts from @phireproject.bsky.social, PANCAIM and PANCAID explore how data, innovation & collaboration drive precision oncology.
πŸŽ™ Moderated by Federica Zanca (EIC)
πŸ“Ί Watch now: www.youtube.com/watch?v=aUhZ...

#CancerResearch #AIinOncology

20.10.2025 11:37 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Congrats Steffi!

24.09.2025 20:45 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Honored to share some big news: I’m now tenured as a W3 Professor of Organic Chemistry @UniCologne! Immensely grateful to all the group members who contributed to this journeyπŸ™ β€” this milestone is ours to share. @ChemUniCologne #OrganicChemistry #Tenure πŸΎπŸŽ‰πŸ§ͺ🧬

24.09.2025 13:10 β€” πŸ‘ 38    πŸ” 3    πŸ’¬ 9    πŸ“Œ 0
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🚨 New PANCAID Masterclass!
How is #AI transforming pancreatic cancer research?
Dr NΓΊria Malats & Sergio Sabroso (CNIO) explain its role in early detection and #precisiononcology.

▢️ https://youtu.be/H-_Xv3H7fZI
@nuriamalats.bsky.socialΒ @cniostopcancer.bsky.socialΒ 

#CancerResearch #PancreaticCancer

23.09.2025 08:02 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
PHIRE, PANCAID, PANCAIM
Approaches to early cancer diagnosis and the impact of artificial intelligence in oncology

Register for our webinar
15 October 2025
14:00 - 15:00 CEST
Registration link: https://events.teams.microsoft.com/event/1fba7a3a-b605-4bcd-9b99-2076044436a7@ea8b78d9-ccc1-45ec-94de-369c8af49a53

More information: https://pancaid-project.eu/news-events/events/

Funded by the European Union

PHIRE, PANCAID, PANCAIM Approaches to early cancer diagnosis and the impact of artificial intelligence in oncology Register for our webinar 15 October 2025 14:00 - 15:00 CEST Registration link: https://events.teams.microsoft.com/event/1fba7a3a-b605-4bcd-9b99-2076044436a7@ea8b78d9-ccc1-45ec-94de-369c8af49a53 More information: https://pancaid-project.eu/news-events/events/ Funded by the European Union

Join our webinar β€œApproaches to Early Cancer Diagnosis and the Impact of Artificial Intelligence in Oncology”!
@phireproject.bsky.social, #PANCAIM & @pancaid.bsky.social are proud to discuss how AI is transforming #oncology.

πŸ”— Register: events.teams.microsoft.com/event/1fba7a...

#CancerResearch

04.09.2025 07:48 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
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New #award for #EarlyCareerResearchers!

You can now apply for our Meeting Award, which will support participation in the conference #Biochemistry 2026 (March 16-18, 2026) with 500 € and give you a one-year, free membership in our Division!

en.gdch.de/network-s...

#ChemSky #ChemBio #ECR @gdch.de

02.09.2025 11:18 β€” πŸ‘ 5    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Genomic and chemical characterization of cytotoxic Ahp-cyclodepsipeptides from Phormidium using Thamnocephalus platyurus bioassay Toxic benthic cyanobacterial mats have been identified globally as a potential health hazard since they can produce potent cyanotoxins. Such mats have…

Thrilled to see our study on novel toxins from cyanobacteria blooms in #Fribourg in STOTEN! Our results indicate that Phormidium is the producer of cyanopeptolins, whose side chains are crucial for their activity.

Great collaboration with Pilar Junier

www.sciencedirect.com/science/arti...

01.07.2025 14:25 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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πŸ”¦ PANCAID Partner Spotlight: @uu.se
The labs of @masoodkamali.bsky.social & @globischlab.bsky.social bring cutting-edge EV, proteomics & metabolomics expertise to PANCAID.
🟣 Working together on biomarker discovery in WP2.

@scilifelab.se
#Metabolomics #CancerResearch

17.06.2025 11:49 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Thanks for highlighting our recent fecal metabolite study.

28.05.2025 20:29 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The Mass Spectrometry Query Language (MassQL) is an open-source language for instrument-independent searching across mass spectrometry data for complex patterns of interest via concise and expressive queries without the need for programming skills.

www.nature.com/articles/s41...

13.05.2025 15:25 β€” πŸ‘ 38    πŸ” 16    πŸ’¬ 1    πŸ“Œ 2

The study was published in the United European Gastroenterology (UEG) Journal. Thanks to our other co-authors Fan Yang, Sara Nikolic and Miroslav Vujasinovic. The aim of our study is to identify fecal metabolites towards a non-invasive detection of pancreatic diseases. #metabolomics #biomarkers

02.05.2025 09:44 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients Background Chronic pancreatitis is a risk factor for pancreatic cancer. Autoimmune pancreatitis is a unique form of chronic pancreatitis that is primarily characterized by its immune mediate etiolog.....

Congrats to @vladyslavdovhalyuk.bsky.social for his first author publication detailing differences in the fecal metabolome of autoimmune and chronic pancreatitis. This study is another close collaboration with our medical experts from @maloehr.bsky.social lab. onlinelibrary.wiley.com/doi/10.1002/...

02.05.2025 09:44 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1
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I am delighted to share our cover art with a creative design by our PhD student @ioannatsiara.bsky.social. Thank you #JAFC for selecting her art work on detailing the discovery of six phase II metabolites specific for a (poly)phenolic dietary intervention. #metabolomics pubs.acs.org/doi/10.1021/...

02.05.2025 09:31 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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πŸŽ‰ Calling all #Metabolomics students & ECRs!

We're offering a $500 AUD travel grant to support attendance at #Metabolomics2025 in Prague, Czechia!

πŸ•› Apply by April 20, 2025 (AEST)

πŸ‘‰ tinyurl.com/metabolomics...

#ANZMetSoc #TravelGrant #Student #ECR

08.04.2025 02:40 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Obituary - Per Jemth

This spring has not been as expected. While we still miss our amazing colleague Per Jemth we try to follow his advice to remember the good times and laugh a lot. www.sciencedirect.com/science/arti...

04.04.2025 15:02 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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There are days in life that shake you.

I’m shattered πŸ’” to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧡

18.03.2025 23:27 β€” πŸ‘ 2003    πŸ” 836    πŸ’¬ 94    πŸ“Œ 93
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Celebrate International Women's Day by reading the Special Issue of the Journal of Proteome Research, highlighting the essential contributions women scientists have madeβ€”and continue to makeβ€”in the fields of Proteomics and Metabolomics. ow.ly/eBcV50TWOpV #InternationalWomensDay πŸ§ͺ

08.03.2025 21:00 β€” πŸ‘ 30    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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Characterizing the Sulfated and Glucuronidated (Poly)phenol Metabolome for Dietary Biomarker Discovery (Poly)phenols, bioactive compounds abundant in plant-based diets, have attracted interest for their potential role in preventing chronic diseases including cardiometabolic and neurodegenerative diseases. This study investigates the global sulfatome and glucuronidated metabolome in urine samples from 100 healthy adults collected pre- and postintervention following a 3-day (poly)phenol-rich intervention consisting of flaxseeds, raspberry powder, and soy milk. Using untargeted mass spectrometric metabolomics combined with selective phase II enzymatic treatment, we detected 156 sulfated and 143 glucuronidated metabolites in urine samples. Significant changes postintervention were observed for 91 sulfates and 94 glucuronides. Receiver operating characteristic curve analysis identified a combination of six polyphenol-derived key metabolites: glucuronidated daidzein and the sulfated compounds of pyrogallol, ferulic acid, 4-methoxyphenol, enterolactone, and resorcinol, which resulted in the best combination with the highest predictive AUC of 0.97. These findings underscore the utility of these metabolites as sensitive and selective biomarkers of (poly)phenol dietary intake.

Characterizing the Sulfated and Glucuronidated (Poly)phenol Metabolome for Dietary Biomarker Discovery #JAFC #MassSpec pubs.acs.org/doi/10.1021/...

03.03.2025 10:05 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Please contact us if you are interested in the investigation of sulfated and glucuronidated metabolites in biological samples and polyphenol interventions.

#metabolomics #chembio #microbiome #phaseIImodifications

04.03.2025 06:56 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Characterizing the Sulfated and Glucuronidated (Poly)phenol Metabolome for Dietary Biomarker Discovery (Poly)phenols, bioactive compounds abundant in plant-based diets, have attracted interest for their potential role in preventing chronic diseases including cardiometabolic and neurodegenerative diseas...

Check out our new publication on the investigation of phase II modifications as dietary markers. Big congrats for the dedicated work by our PhD student @ioannatsiara.bsky.social & our former Master's student BelΓ©n HervΓ‘s Povo in collaboration with Ana Rodriguez-Mateos. pubs.acs.org/doi/10.1021/...

04.03.2025 06:54 β€” πŸ‘ 11    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Beyond excited to announce our in-person symposium to celebrate the 25th anniversary of ChemBioChem/ChemPhysChem!

Advances in Structural Analysis of Biomolecules
From Subcellular Imaging to Drug Design

October 23-24, 2025, Berlin

Please like and share: cbc-cpc2025.org

28.02.2025 16:00 β€” πŸ‘ 34    πŸ” 14    πŸ’¬ 1    πŸ“Œ 0
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It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

08.02.2025 21:21 β€” πŸ‘ 1014    πŸ” 856    πŸ’¬ 83    πŸ“Œ 32
Doctoral scholarship holder chemical biology | University of Antwerp YUFE vacancies

‼️PhD Position in Chemical Biology at the University Antwerp‼️#chembio

βœ”οΈDeadline: ‼️February 20, 2025‼️
βœ”οΈFind full details and submit your application here: www.uantwerpen.be/en/jobs/vaca...

25.01.2025 13:19 β€” πŸ‘ 6    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0

Thank you @stephanhacker2.bsky.social for highlighting me talk at the fantastic #advancesChemBio conference. Great interactions with an exciting schedule in Frankfurt. #ChemBio #microbiome #metabolomics

22.01.2025 12:37 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Amazing talk by @globischlab.bsky.social at #AdvancesChemBio. He talked about studying the changes of metabolites produced by the microbiome in different diseases. Exciting chemical biology tools to enrich metabolites with various functional groups. (1/2) onlinelibrary.wiley.com/doi/10.1002/...

22.01.2025 08:39 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1
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A great meeting on "Advances in Structural Analysis of Biomolecules" celebrating 25 years of ChemBioChem and ChemPhysChem will be happening on October 23rd and 24th in Berlin, Germany.
If you want to participate, you can already register and send in an abstract.
#chemsky #ChemBio
www.cbc-cpc2025.org

20.01.2025 16:40 β€” πŸ‘ 14    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

As the #pancreaticcancer and #liquidbiopsy community on Bluesky is growing, we're excited to see more and more familiar faces from our consortium over here 🀩
To help you find each other, we've created a Starter Pack of PANCAID member institutions and researchers.

#pancreas

‡️‡️‡️
go.bsky.app/BgEQXbt

18.01.2025 09:57 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Now live at the European Parliament in Brussels, Belgium, our stakeholder dialogue event is in full swing!

Bringing together policymakers, patients, advocates and researchers, we discuss how to excel #earlydetection of #pancreaticcancer

15.01.2025 15:11 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Excited for PANCAID’s 3rd General Assembly this week in Brussels! πŸ‡§πŸ‡ͺ

@maloehr.bsky.social @malinasund.bsky.social @cniostopcancer.bsky.social @hps2022.bsky.social @globischlab.bsky.social @qmul.ac.uk @collectiveminds.bsky.social

#PANCAID #HorizonEurope #PancreaticCancer

13.01.2025 10:55 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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The Division of Biochemistry of the @gdch.bsky.social wishes you a happy new year!

We had a great 2024 with an amazing Biochemistry meeting in Dortmund. If you had an outstanding PhD thesis or publication in your group in 2024, consider nominating for our Young Scientists Award. #chemsky #ChemBio

01.01.2025 13:36 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

@globischlab is following 20 prominent accounts