Precision Oncology Ireland

Siobhan Gaynor, Advanced Cancer Patient Council member and patient researcher; Prof Donal Brenan, UCD Professor of Gynae-Oncology, Consultant Gynaecological Oncologist at the Mater Hospital, and Deputy-Director of POI; Prof Walter Kolch, Director of Precision Oncology Ireland and Systems Biology Ireland (based at UCD); Dr Siobhan Roche, Director of Science for the Economy, Taighde Éireann–Research Ireland; Prof Kate Robson Brown, UCD Vice-President for Research, Innovation and Impact.

Minister James Lawless has launched Phase 2 of Ireland’s leading and largest ever cancer research programme, @precisiononcire.bsky.social. The programme is co-funded through Research Ireland, industry and the not-for-profit sector. Read more: www.researchireland.ie/news/precision-oncology-ireland/

POI2 is a cancer research consortium of academic, charity, industry & clinical partners led by @sysbioire.bsky.social in @ucddublin.bsky.social & supported by @researchireland.ie

@tcddublin.bsky.social @dublincityuni.bsky.social @ucc.ie @uniofgalway.bsky.social @rcsi.bsky.social

With POI-2, our network of researchers grows stronger. We're strengthening our links with clinical partners and bringing in additional expertise in dry and wet-lab research, creating an integrated, collaborative research platform.

One of POI's greatest successes has been developing an organised structure of charity, industry, academic and patient partners, united in a common goal. POI-2 expands this network further, welcoming back established partners and embracing new voices with valuable expertise

Since 2019, POI has worked to accelerate the development of personalised cancer therapy & diagnostic options. Today we begin Stage 2 of our journey, building on strong foundations and expanding our collaborations to drive innovation & shape the future of cancer care.

Since 2019, POI has driven huge research impacts, from biological insights to training the next generation of researchers. On #WorldCancerResearchDay, we’re proud to share our new brochure, developed with science journalist Claire O'Connell, highlighting these achievements

tinyurl.com/jnhs762h

@sysbioire.bsky.social @researchireland.ie @ucdresearch.bsky.social @medunigraz.at @goldlab.bsky.social @ap-hp.bsky.social

New blog: September marks #ChildhoodCancerAwarenessMonth worldwide. Our latest blog post details how POI researchers are working tirelessly to improve treatment options and quality of life for the most vulnerable of cancer patients.
tinyurl.com/yfj6trcf

📢We've extended our poster abstract deadline to Sept 22 to accommodate anyone returning to campus who would still like to submit & attend #ICSB2025! Please spread the word!

Submit your poster abstract here: icsb2025.com

#personalisedmedicine #computationalmodelling
@precisiononcire.bsky.social

Cancer Revolution: Science, Innovation and Hope

News post: We recently attended the launch event for Breakthrough Cancer Research's "Cancer Revolution: Science, Innovation and Hope" exhibition.

Hear how we got on and find out more details on this amazing public exhibit in the link below.

www.precisiononcology.ie/news/news/20...

Thrilled to join Breakthrough Cancer Research's "Cancer Revolution" launch — showcasing how research transforms patients’ lives. POI & @sysbioire.bsky.social curated a display on the synergistic power of combining lab research and computational analysis to enhance & personalise patient care

Prof. Kwang-Hyun Cho is chair of the Drug Discovery, Development & Resistance session at #ICSB2025. Hear more information about the upcoming conference & why you should check out this session.

Still time to register! ➡️ icsb2025.com

@ucddublin.bsky.social @precisiononcire.bsky.social

Happy to chair a session on cell and pathway engineering at ICSB2025.com featuring e.g. an inspiring talk by @olivierpertz.bsky.social on pathway dynamics, cell fates and optical tools. Contributed talk deadline is today, Sept 1st for poster abstracts. Hope to see you in Dublin in October! #ICSB2025

Final opportunity to submit an oral abstract for the leading systems-biology conference in the world. ICSB will be held in Dublin this October and features an exceptional line-up of speakers. Don't miss your chance to join them and share your latest findings

The final morning sessions on AI & ML in Systems Biology should be of great interest to POI researchers and collaborators.

Oral submissions still open until this Friday, poster submissions closing 1st Sept

#ICSB2025 #SystemsBiology #PersonalisedMedicine #AI #ML #Bioinformatics

The final day of #ICSB2025 on Thurs, Oct 9, will finish with 3 more outstanding breakout sessions.
✨Clinical Decision Support Tools
✨Evolution & Development
✨AI/ML Approaches in Systems Biology

For more info: bit.ly/4mPNfGQ
@ucddublin.bsky.social @ucd-chas.bsky.social @precisiononcire.bsky.social

⏰ Just over a week to submit your oral abstract for ICSB2025!

🗓 Oral deadline: 12, Fri 1 Aug
🗓 Poster deadline: 12, Mon 1 Sept (early submission encouraged)

Session topics include: #DigitalTwins, #Cancer, #DrugDiscovery, #DataIntegration & more
🔗 tinyurl.com/4xmn2uz4

@sysbioire.bsky.social

Great to have an additional social option for #ICSB2025 – a walking tour of Dublin. It's a small city centre, so walking is the easiest way to see it! icsb2025.com/social-progr... #systemsbiology

📢Great news! The abstract submission deadline for #ICSB2025 has been extended, allowing for broader participation & a more diverse scientific program.

Oral presentations deadline: 12 PM, 1 Aug
Poster presentations deadline: 12 PM, 1 Sept

Submit now: bit.ly/4k9J5IM

@ucddublin.bsky.social

Amazing work! Well done Afshin

After 5 successful years of the Invisible Spectrum initiative, we're proud to present our results, highlighting not only the success of the initiative but also presenting an organisational blueprint for other groups who wish to engage in similar work
t.co/34aJLVoTSD

Prof. Walter Kolch

Prof. Jonathan Bond

Dr. Amelie Trinquand

Delighted to spend Tuesday taking part in the Children's Cancer Unit Charity Research Workshop at @qubelfastofficial.bsky.social where we discussed with colleagues how to further promote cross-border collaborations in paediatric oncology research. 💛 @precisiononcire.bsky.social #childhoodcancer

Saturated fat exacerbates mitochondrial dysfunction through remodelling of ATP production and inflammation in Barrett’s oesophagus compared to monounsaturated fat, particularly in contrast to oesophag... Obesity-related oesophageal adenocarcinoma (OAC), arising from Barrett’s oesophagus (BO), incidence rates are rising coincident with high-fat diets. H…

Congratulations to all authors on this study just published in Neoplasia, which not only demonstrated influence of saturated fat on cancer progression in the oesophagus but provides a wonderful example of the collaborative strength of the POI consortium tinyurl.com/yc7aaeb4 @sysbioire.bsky.social

Powerful article published today to mark #worldbarrettsday, highlighting the importance of early detection in #OesophagealCancer. POI is enabling development of patient biobanks to support vital research and work towards better patient outcomes #ResearchisCare

Higher-ed minister promises to strengthen Irish research At a recent IUA event, Minister James Lawless set out his visions for the future of Ireland's research and innovation.

Ireland will be placing a stronger focus on higher education, research and skills as the “foundational pillars” for its forthcoming economic strategy.

Check out the wonderful feature in @siliconrepublic.bsky.social on SBI/POI Investigator, Luis Iglesias-Martinez, as he discusses the MAGIC-I programme & the promising future of using AI for better childhood cancer treatment.
@precisiononcire.bsky.social
www.siliconrepublic.com/machines/ucd...

@ucddublin.bsky.social @ucdresearch.bsky.social @sysbioire.bsky.social @tcddublin.bsky.social @harvardmed.bsky.social @univ-amu.fr @researchireland.ie

Great to see this paper published straight after World Ovarian Cancer Day: new research from Prof. Donal Brennan & collaborators highlights a potent immunosuppressive effect of lipids within ovarian ascites and a potential new avenue for development of immunotherapies

www.ucd.ie/medicine/new...

Today marks #WorldOvarianCancerDay With the majority of ovarian cancer patients presenting with metastatic disease at diagnosis, it's so important to recognize the potential early warning signs. Always remember, BEAT - Bloating, Eating changes, Abdominal pain & Toilet changes

YouTube video by Systems Biology Ireland Official 24th Annual International Conference on Systems Biology (ICSB 2025)

We're honored to be hosting #ICSB2025 in Dublin this October😊Currently working with colleagues from across the systems biology community on what promises to be an inspiring programme!

Register: icsb2025.com/registration/

@ucddublin.bsky.social
@precisiononcire.bsky.social

youtu.be/i8ekr_KmwvA?...