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Tumour-Immune Cell Dynamics Lab

@witherslab.bsky.social

We are the Withers lab, based at the @oxcio.bsky.social at the Nuffield Department of Medicine, Oxford. Our research is focused upon understanding how immune cells adapt to, and are changed by tissues, particularly the tumour microenvironment.

53 Followers  |  33 Following  |  5 Posts  |  Joined: 22.01.2025
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Posts by Tumour-Immune Cell Dynamics Lab (@witherslab.bsky.social)

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…(ii) Adoptively transferred Tmem33-/- (KO) OT-I CD8+ T cells massively expand in B16F10-OVA and show greater Tpex accumulation in tumours and draining lymph nodes compared to Tmem33+/+ (WT) OT-I (thank you @witherslab.bsky.social )…. 6/10

05.01.2026 15:30 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Parkes lab pre-print alert! β€˜TMEM33 deletion potentiates anti-tumor CD8⁺ T cell immunity.’ Led by mtjackson101.bsky.social. Full bluetutorial follows! 1/10 www.biorxiv.org/content/10.6...

05.01.2026 15:30 β€” πŸ‘ 22    πŸ” 10    πŸ’¬ 1    πŸ“Œ 1
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We’re happy to be in Liverpool for this years @britsocimm.bsky.social congress:
In today’s β€œWhat’s hot in cancer immunology?” session, Prof David Withers presented our new data on an orthotopic colorectal cancer model for the first time! 🐭πŸ’ͺ

03.12.2025 17:02 β€” πŸ‘ 16    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Today, our PostDoc @lisav17.bsky.social has presented her progress on alternative experimental approaches to our current Kaede system in the @oxcio.bsky.social weekly seminar!
πŸ§¬πŸ”¦

13.11.2025 14:01 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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I am grateful for the experience I gained, the people I met & the amazing support in my lab group!

I end this day full of excitement for what’s next to come πŸ”¬πŸ§«

10.11.2025 22:37 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Today I successfully passed my Transfer of Status from β€˜DPhil Candidate’ to β€˜DPhil Student’. It was amazing to present my past years work in detail & get feedback!
It’s a steep learning curve but today was rewarding! πŸ“ˆ

10.11.2025 22:37 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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In this weeks @oxcio.bsky.social seminar, our PostDoc Pascale presented her current progress on setting up #SingleCellSequencing experiments and their analysis for the @witherslab.bsky.social in Oxford! πŸ–₯οΈπŸ’‘πŸ­
Exciting!!!

23.10.2025 12:50 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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Today we kicked off the @oxcio.bsky.social weekly seminar presenting our most recent achievementsπŸ”¬
Our PostDoc @nabinapun.bsky.social gave insight into her research on myeloid cells in the TME our RA @ioannisguida.bsky.social presented a conclusion of his work in the #WithersLab before he leaves us!

11.09.2025 17:47 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 2
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Yesterday we finished with prize-giving and drinks in the gardenπŸ₯‚πŸŒ±! πŸ† Posters for Bas, Cindy & CharlotteπŸ“ƒ; postdoc talk for Qian πŸ‘©β€πŸ« & best embossing artwork for Group8 πŸ§‘β€πŸŽ¨ Shoutout to Lisha for the Rhodes House tours, acknowledging its history, the good and the uncomfortable βš–οΈ. What a day! #CIOawayday

10.07.2025 07:15 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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✨ Kicking off #CIOawayday with our senior PIs sharing the experiments that changed their careers πŸ§‘β€πŸ”¬πŸ‘©β€πŸ”¬πŸ§« A reminder that serendipity, curiosity, and pub chats can spark groundbreaking ideas πŸ€“ Clearly science thrives on kindness and collaboration and we got a lot of that in #CIO πŸ˜‰πŸ™ƒ #ScienceLife

09.07.2025 11:37 β€” πŸ‘ 9    πŸ” 5    πŸ’¬ 0    πŸ“Œ 2
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We’re at the #OCION Symposium today @oxfordcancer.bsky.social
πŸ’‘πŸ§¬A full day of inspiring talks, cutting-edge science, and collaborative energy as we explore the vibrant cancer research landscape across Oxford. From immuno-oncology to early detection & precision medicine #OxfordCancer #CancerResearch

13.06.2025 09:11 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Today we’re at the @britsocimm.bsky.social Bristol Immunolgy Group presenting some of our recent data!

11.06.2025 11:01 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 0    πŸ“Œ 2
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Oxford Liver Cancer Centre of Excellence 2025 Symposium An event focused on advancing scientific collaboration and improving outcomes for liver cancer.

There are only a few tickets left for this year's Oxford Liver Cancer Centre of Excellence Symposium!

Ensure to secure your place before registration closes on the 5th of May! ⬇️ @medsci.ox.ac.uk #LiverCancer

www.eventbrite.co.uk/e/oxford-liv...

30.04.2025 07:25 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Prof. Tim. Elliott introducing Group Leader David Withers before his talk

Prof. Tim. Elliott introducing Group Leader David Withers before his talk

David Withers presenting immune cell dynamics

David Withers presenting immune cell dynamics

πŸ€“ Great talks today at the Spacial Biology seminar from OCION and @medsci.ox.ac.uk

Inspiring inisghts from Simon Leedham and our very own David Withers! @witherslab.bsky.social
#SpacialBiology #ImmuneDynamics #OxfordResearch #OCION

29.04.2025 16:32 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Fantastic talk from our #CIO PI, David Withers @witherslab.bsky.social, this morning at @imm.ox.ac.uk on tumour immune cell dynamicsβ€”great insights from an elegant mouse model to track entry and resident immune cells within tumours🐭🧫πŸ§ͺ #TumourImmunology #NK #Tregs

14.03.2025 10:42 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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David Withers PhD David Withers - Group Leader in Experimental Cancer Immunology

🚨Today at our #CIOseminars Prof David Withers @witherslab.bsky.social will share his group’s latest research:

πŸ‘‰Investigating Intratumoural Treg Recruitment and Retention

πŸ“NDMRB Seminar room ⏰ 13h

Join us! 🧬πŸ”₯ #Immunology #CancerResearch #Tregs #CIOseminars

www.immonc.ox.ac.uk/team/david-w...

06.02.2025 11:08 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0