bioRxiv Immunology

A Humanized IFN-γ Mouse Model Reveals Skin Eschar Formation, Enhanced Susceptibility and Scrub Typhus Pathogenesis https://www.biorxiv.org/content/10.1101/2025.08.01.668084v1

Spatial Transcriptomics Reveals that the Local Immune Response to Placental Guinea Pig https://www.biorxiv.org/content/10.1101/2025.08.01.668085v1

TASL is required for age-related B cell formation and autoimmunity https://www.biorxiv.org/content/10.1101/2025.08.01.668068v1

GM-CSF orchestrates monocyte and granulocyte responses to Cryptococcus gattii https://www.biorxiv.org/content/10.1101/2025.08.01.668083v1

Hemoglobin alpha regulates T-lymphocyte activation and mitochondrial function https://www.biorxiv.org/content/10.1101/2025.08.01.668160v1

Engineering a Juxtamembrane-Targeting CAR T-Cell Against Mesothelin: A Novel Binder Resilient to Shed Antigen in Ovarian and Pancreatic Cancer https://www.biorxiv.org/content/10.1101/2025.08.02.668276v1

Interplay between Hyperglycemia and Chikungunya Virus Infection: Pathophysiological Insights from Murine Model https://www.biorxiv.org/content/10.1101/2025.08.01.668212v1

Pathologic profibrotic activation of distinct myeloid cell subsets in a model of impaired healing after anterior cruciate ligament reconstruction https://www.biorxiv.org/content/10.1101/2025.07.31.667715v1

Bioactive Enhanced Adjuvant Chemokine Oligonucleotide Nanoparticles (BEACONs) for Mucosal Vaccination Against Genital Herpes https://www.biorxiv.org/content/10.1101/2025.07.31.667899v1

Stabilization of H5 highly pathogenic avian influenza hemagglutinin improves vaccine-elicited neutralizing antibody responses https://www.biorxiv.org/content/10.1101/2025.07.30.667762v1

Integrative immune subtyping of HNSCC reveals clinically relevant phenotypes and treatment-associated transitions https://www.biorxiv.org/content/10.1101/2025.07.31.667850v1

T cell ectosomes promote antibody responses through cognate TCR-pMHC interactions https://www.biorxiv.org/content/10.1101/2025.07.30.667776v1

Single-cell and spatial transcriptomic analyses of gene therapy-associatedretinal inflammation in non-human primates https://www.biorxiv.org/content/10.1101/2025.07.31.667874v1

Immune cell senescence drives responsiveness to immunotherapy in melanoma https://www.biorxiv.org/content/10.1101/2025.07.31.667878v1

Stainless Steel-Synthesized Gold Nanoparticles: Insights into Blood-Brain Barrier Permeability and Microglial Interaction. https://www.biorxiv.org/content/10.1101/2025.07.30.667668v1

Phagocytosis of primary human macrophages is elevated by ex vivo supplementation with n-3 PUFA https://www.biorxiv.org/content/10.1101/2025.07.30.667640v1

Clostridioides difficile toxin A and toxin B inhibit toxin-specific adaptive immune responses through glucosyltransferase-dependent activity https://www.biorxiv.org/content/10.1101/2025.07.30.667646v1

Generation of effector CD4+ T cells from Human iPSC https://www.biorxiv.org/content/10.1101/2025.08.01.667959v1

Maternal low-fat and high-fat diet decreases survival and alters cytokine signaling in neonatal mice with Staphylococcus epidermidis sepsis https://www.biorxiv.org/content/10.1101/2025.07.30.667518v1

Spatio-temporal regulation of ligand trafficking and TLR9 activation involves PIEZO1 mechanosensing in human plasmacytoid dendritic cells https://www.biorxiv.org/content/10.1101/2025.07.31.667789v1

B7-H4 Binds Galectin-9 Glycosylation-Dependently and Attenuates Galectin-9-Mediated CD28/AKT Activation and T Cell Death https://www.biorxiv.org/content/10.1101/2025.07.31.666261v1

The earliest changes in the translatome upon human T cell activation https://www.biorxiv.org/content/10.1101/2025.07.31.667903v1

CD40 agonistic-monovalent streptavidin fusion antibody for targeted neoantigen peptide delivery and potent cancer vaccination https://www.biorxiv.org/content/10.1101/2025.07.30.663779v1

Quantum Convolutional HLA Immunogenic Peptide Prediction (Q-CHIPP): Next-Generation Neoantigen Prediction with Quantum Neural Networks https://www.biorxiv.org/content/10.1101/2025.07.29.667313v1

miR-146a-3p packaged in small extracellular vesicles triggers fetal membrane inflammation in response to viral dsRNA through activation of Toll-like Receptor 7 and 8 https://www.biorxiv.org/content/10.1101/2025.07.29.667498v1

Multivalent Tri-Functional T-cell Engagers by Chemically Induced Protein Self-Assembly https://www.biorxiv.org/content/10.1101/2025.07.29.667528v1

CD38⁺ Endothelial Remodeling Defines Spatially Diverse Vasculopathy Programs in Rapidly Advancing Oral Inflammation https://www.biorxiv.org/content/10.1101/2025.07.29.667333v1

Spatial organization of pulmonary type 2 inflammation by a macrophage-derived cholesterol metabolite https://www.biorxiv.org/content/10.1101/2025.07.29.666625v1

CD45 sequestration lowers the signaling threshold in lymphocytes and enhances anti-tumor immunity https://www.biorxiv.org/content/10.1101/2025.07.29.667400v1

The Cornea Harbors a Tricellular Neuro-Immune Niche that Underpins Touch Sensation https://www.biorxiv.org/content/10.1101/2025.07.28.664937v1