bioRxiv Immunology

A conserved transcriptional backbone and rewiring of gene-regulatory networks in activated human CD4⁺ T cells https://www.biorxiv.org/content/10.1101/2025.11.25.687998v1

Quantifying maternal antibody transfer to colostrum and cord blood reveals virus-specific selectivity in dogs https://www.biorxiv.org/content/10.1101/2025.11.24.690260v1

Sustained Humoral Activation through self-amplifying mRNA Vaccination Enhances Longitudinal Antibody Function in a Phase III Trial https://www.biorxiv.org/content/10.1101/2025.11.25.690547v1

NLRP1 Shapes Immune and Inflammatory Signatures in Human Melanoma but Not in Mouse Models https://www.biorxiv.org/content/10.1101/2025.11.24.690170v1

A Globally Representative Immunopeptidomics Approach to Identify Population-Wide Vaccine Candidates https://www.biorxiv.org/content/10.1101/2025.11.25.690604v1

Sexual dimorphism in zymosan-induced arthritis is linked with a higher IFN response in myeloid cell subsets that faithfully recapitulate RA synovial cell clusters https://www.biorxiv.org/content/10.1101/2025.11.24.690174v1

GM-CSF instructs vertebral emergency myelopoiesis in neuropathic pain https://www.biorxiv.org/content/10.1101/2025.11.23.690022v1

Probiotic lactic acid bacteria induce regulatory functions in γδ T cells https://www.biorxiv.org/content/10.1101/2025.11.21.689796v1

TNF-α-Driven Systemic Inflammasome Hyperactivity Links Psoriatic Inflammation to monocyte inflammatory response and platelet activation https://www.biorxiv.org/content/10.1101/2025.11.24.690330v1

4-Hydroxynonenal suppresses IL-10 production during infection https://www.biorxiv.org/content/10.1101/2025.11.24.690094v1

Endothelial cell MHC molecules are necessary and sufficient to reject 3D-printed human skin grafts in an advanced human immune system mouse https://www.biorxiv.org/content/10.1101/2025.11.24.689811v1

Immunological Differences in Atopic Dermatitis Across Age Groups: Insights from Single-Cell Multi-Omics https://www.biorxiv.org/content/10.1101/2025.11.22.689843v1

Restoration of MAIT cell function in healthcare-associated bacterial infections supports recovery of carbapenem efficacy against resistant bacteria https://www.biorxiv.org/content/10.1101/2025.11.21.689870v1

Nuclear factor kappa B subunits and IkappaB family are modulated in the ovine endometrium during early pregnancy https://www.biorxiv.org/content/10.1101/2025.11.22.689904v1

Uncovering structural determinants of peptide recognition by public and private T-cell receptors https://www.biorxiv.org/content/10.1101/2025.11.23.690020v1

Contemporary HIV-1 envelope pseudovirus panels for detecting and assessing B cell lineages with broadly neutralizing antibody potential https://www.biorxiv.org/content/10.1101/2025.11.21.689752v1

Neonatal Platelets Differentiate Monocytes to a Myeloid Derived Suppressor Cell Phenotype https://www.biorxiv.org/content/10.1101/2025.11.21.689809v1

Effects of a novel proteasome inhibitor, UR238 on the tumor immune microenvironment and growth in epithelial ovarian cancer https://www.biorxiv.org/content/10.1101/2025.11.21.689729v1

Galectin-1 induces macrophage immunometabolic reprogramming, modulates T cell immunity and attenuates atherosclerotic plaque formation https://www.biorxiv.org/content/10.1101/2025.11.21.689721v1

Major histocompatibility complex class II-expressing bone marrow megakaryocytes activate CD4+ T cells and induce regulatory T cell fate https://www.biorxiv.org/content/10.1101/2025.11.21.689743v1

Single-Cell Multi-Omics Dissects Transcript Isoform and Immune Repertoire Dynamics in Human Immunosenescence https://www.biorxiv.org/content/10.1101/2025.11.21.689731v1

OspA Antibodies Inhibit the In vitro Transmigration of Borreliellia burgdorferi https://www.biorxiv.org/content/10.1101/2025.11.20.689610v1

mCytoCounter, a deployable somatic cell counting device for the assessment of mastitis in dairy farms https://www.biorxiv.org/content/10.1101/2025.11.19.689399v1

Antigen-reactive CD4+ T cells after SARS-CoV-2 vaccination show divergent phenotypic states with or without restimulation bias https://www.biorxiv.org/content/10.1101/2025.11.19.688845v1

Congenital CMV infection drives oligoclonal expansion of cytotoxic γδ T cells from early fetal progenitors https://www.biorxiv.org/content/10.1101/2025.11.20.689355v1

EBV INFECTION OUTCOMES DETERMINED BY MONOCYTE AND TREG-DRIVEN IMMUNE DYNAMICS IN AN EX VIVO PBMC MODEL https://www.biorxiv.org/content/10.1101/2025.11.20.689441v1

Gelsolin Counteracts ER Stress-Driven Inflammatory Circuits in Psoriasis-like Dermatitis https://www.biorxiv.org/content/10.1101/2025.11.20.689413v1

ATRX Deficiency Drives Aberrant Type I Interferon Signalling Through cGAS-Dependent Transcriptional Dysregulation https://www.biorxiv.org/content/10.1101/2025.11.19.685761v1

Leveraging mathematical models to predict and control T-cell activation https://www.biorxiv.org/content/10.1101/2025.11.20.689432v1

Diverse infection models demonstrate robust resistance of Mycobacterium tuberculosis to innate immunity https://www.biorxiv.org/content/10.1101/2025.11.20.687493v1