Michael Gantier

IsomiR stoichiometry changes as disease biomarkers. Gantier, Gearing and colleagues demonstrate, through analysis of small RNA sequencing data, that quantification of microRNA isoforms enables identification of accurate biomarker candidates overlooked in aggregated microRNA data. A ratio-based approach to isoform-level biomarker discovery is presented, measuring the relative abundance of alternate isoforms to provide internal normalisation within a microRNA.

#MTNA

Excited to share our latest work on how microRNA length variants can be leveraged as disease biomarkers. Congratulations to Alex McAllan for all her work on this! doi.org/10.1016/j.om...

Co-Chairs, Michael Gale, Jr. and @ramlabuw.bsky.social invite abstract submissions for Cytokines2025. Topics include adaptive immunity, cytokine signaling, interferon stimulated genes, structure- function, and more. Submit: seattle.cytokinesociety.org/call-for-abs...
Deadline is May 18, 2025.

RNA Victoria minisymposium | RNA Victoria Network

For all RNA scientists in the Melbourne area: Join us at the next RNA Victoria Minisymposium on 27th of March at the Hudson Institute of Medical Research - details about the speakers and free registration at www.rnavic.com

Gomez-Diaz, @v-hornung.bsky.social et al. show that mice lacking RNase T2 display an inflammatory phenotype in a TLR13-dependent manner, even under germ-free conditions, suggesting that RNase T2 plays an important role in limiting self-RNA recognition https://buff.ly/4jG49Gy