Martin Plöderl

Evening

I think that’s basically correct, and the methods are selected for maximizing interest but also for falling into the goldilocks zone of understanding: simple enough so that readers don’t feel entirely overwhelmed, complex enough so that they can’t quite see through and understand the limitations.

Thesis:
research in our field is driven more by new methods than by theories.

Meet the researcher aiming to halt use of ‘fundamentally flawed’ database linking IQ and nationality Rebecca Sear Rebecca Sear is on a mission to convince publishers to retract articles that use a database that purports to rank countries based on intelligence. To maintain the integrity of scientif…

Rebecca Sear is on a mission to convince publishers to retract articles that use a database that purports to rank countries based on intelligence.

Ich hoffe dass jetzt endlich ernst gemacht wird mit der digitalen Souveränität in Europa - vielleicht kann das auch einer der dringend nötigen Wachstumsbereiche werden

"Digitale Auslöschung": Wie US-Sanktionen einen europäischen Richter lahmlegen Nicolas Guillou ist von beinahe allen digitalen Diensten dieser Welt gesperrt – von Amazon bis Paypal. Europa wirkt dagegen völlig machtlos

Diese Geschichte ist unfassbar.
Weil der Trump-Regierung die Arbeit des Internationalen Strafgerichtshofs nicht passt, wird ein französischer Richter digital de facto ausgelöscht und bekommt keine Kreditkarte und kein Bankkonto mehr:

The loss of efficacy of fluoxetine in pediatric depression: explanations, lack of acknowledgment, and implications for other treatments Fluoxetine is among the most used antidepressants for children and adolescents and frequently recommended as first-line pharmacological treatment for pediatric depression. However, in contrast to earl...

The loss of efficacy of fluoxetine in pediatric depression: explanations, lack of acknowledgment, and implications for other treatments - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

😆

this is mesmerizing

Ernst Kahl: Künstler nach langer Krankheit gestorben Ernst Kahl gewann den Wilhelm-Busch-Preis. Er zeichnete unter anderem für die »Süddeutsche Zeitung« und lieferte Skripte für »Werner – beinhart!«. Nun ist der norddeutsche Künstler gestorben.

Wie kann man 53 werden und erst anlässlich seines Todes Ernst Kahl und seiner Großartigkeit erfahren???
www.spiegel.de/kultur/ernst...

Psychiatrie-Konferenz mit exzellenten ReferentInnen und, tata tusch: ohne Interessenkonflikte mit der Pharma-Industrie! 👏👏👏
Auch online
www.hdmed.de/psychiatries...

Welcome to the world of "pure" biological psychiatry
"MDD is increasingly understood as a disorder of dysregulated neuroplasticity rather than solely of neurotransmitter imbalance"
www.biorxiv.org/content/bior...

@padbergthorsten.bsky.social @joannamoncrieff.bsky.social @mad-in-america.bsky.social

Easier to Refill Than Review: Antidepressant Prescribing in Primary Care Researchers found that for many doctors, renewing antidepressant prescriptions feels safer and faster than helping people taper, and that most current interventions fail to address the pressures…

The study describes how short visits, weak follow-up systems, and fragmented relationships leave responsibility for stopping antidepressants on the patient’s shoulders, even when guidelines call for regular review.

By Richard Sears

Excellent review on microbiome & autism research

"there may be a sense that “where there’s smoke, there must be fire,” but experience from other fields (social psychology, candidate gene association studies, neuroimaging...) has shown that actually there can sometimes just be lots of smoke.

Polygenic Contributions to Lithium Augmentation Outcomes in Unipolar Depression This cohort study examines data for patients with major depressive disorder who did not respond to antidepressant therapy after they underwent lithium augmentation to gauge the association of polygeni...

I bet 5000 Euro that this can't be replicated in an independent study

jamanetwork.com/journals/jam...

On Dangers of Preprints Antivaxxery in scientific literature – are preprints to blame?

I wrote about Tsatsakis, Aschner and Docea already back in 2021...
forbetterscience.com/2021/10/06/o...

This is as fascinating as sobering!
Declaration of interest: I/we have uploaded several preprints 😆

Unbelievable...

Exclusive: RW exclusively exposes fraud and antivaxxery by Tsatsakis, Aschner, Abdolhahi, Domingo, Svistunov and Docea. Totally exclusively.
forbetterscience.com/2025/11/19/a...

Springer Nature flags paper with fabricated reference to article (not) written by our cofounder Tips we get about papers and books citing fake references have skyrocketed this year, tracking closely with the rise of ChatGPT and other generative large language models. One in particular hit clo…

Springer Nature flags paper with fabricated reference to article (not) written by our cofounder

Initial treatment choices to achieve sustained response in major depression: a systematic review and network meta‐analysis Major depression is often a relapsing disorder. It is therefore important to start its treatment with therapies that maximize the chance of not only getting the patients well but also keeping them we....

Also discussed in this very important review by @toshi-frkw.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...

I think that confounding relapse with withdrawal is an issue with this trial design
doi.org/10.1177/2045...

😍

PsychoSociety | Dirk Richter | Substack Anything related to the human psyche and modern society and in between. Click to read PsychoSociety, by Dirk Richter, a Substack publication. Launched a day ago.

I have just launched 'PsychoSociety', a Substack covering anything related to the human psyche and modern society.
Please subscribe to this free newsletter to keep updated.
dirkrichter.substack.com

Restoring TADS: RIAT reanalysis of the Treatment for Adolescents with Depression Study - PubMed BackgroundThe Treatment for Adolescents with Depression Study (TADS) continues to influence international clinical practice guidelines for adolescent depression.ObjectiveWe assessed TADS' effectiveness and harms through a Restoring Invisible and Abandoned Trials (RIAT)-led reanalysis.MethodsTADS was …

pubmed.ncbi.nlm.nih.gov/40421808/

“In Switzerland you can have muesli for tea and in Britain you can have a measly imitation for breakfast but in America you will soon be able to have measles anytime at all.” Sayings of Confuseus

This is an excellent read for a non-genetics-expert like me. 🙏

@jayjoseph22.bsky.social

The missing heritability question is now (mostly) answered Not with a bang but with a whimper

I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵