Poirazi Lab

Distinct dendritic integration strategies control dynamics of inhibition in the neocortex Dendrites critically influence single-neuron computations, but their role in neocortical GABAergic interneurons (INs) remains poorly understood. We fo…

📣New study in Neuron, featuring modeling insights: "Cell-Specific Dendritic Integration in Cortical GABAergic Interneurons"! It reveals PV & SST interneurons compute differently. This highlights how distinct dendrites enable specialized brain computations!

www.sciencedirect.com/science/arti...

📯We, the Poirazi Lab at IMBB-FORTH, are thrilled to announce an open PhD Student position!

🗝️Key Research Areas: AI, Machine Learning, Brain-Inspired Computing, Neuronal Circuits.

📅Application Deadline: July 7, 2025.

Find out more about the position on our webpage: dendrites.gr?p=2825

Have you tried building neuronal models with #DendroTweaks? It’s a Python toolbox we made to help you visualize and customize single-neuron models with active dendrites. And it's just got a major update! ✨ Here's what's new: 🧵

The renowned #BrainConferences are coming to Crete, Greece for the first time! This is a unique opportunity for young scientists in Greece and abroad to learn all about the Adaptive Mind from the best scientists in the field.

Join us for the DendroTweaks tutorial at CNS*2025

Interested in neuronal modeling?

We are hosting a hands-on tutorial at CNS*2025, co-organized with the Jaxley team.
Check out the full tutorial description here:
cns2025florence.sched.com/event/25kVa/...

📅July 5,📍Florence, Italy
See you there!

Spontaneous Dynamics Predict the Effects of Targeted Intervention in Hippocampal Neuronal Cultures Dissociated neuronal cultures on High-Density Multi-Electrode Arrays (HD-MEAs) provide a controllable in vitro platform to systematically investigate the formation, development, and functioning of neu...

💡Exciting NEUREKA Project news from Vassanelli & Poirazi Labs: A new IC method on HD-MEAs shows we can predict neuronal network causal architecture using spontaneous activity.
www.biorxiv.org/content/10.1...
#Neuroscience #HDMEA #NeuronalNetworks #FunctionalConnectivity

From Morphology to Computation: How Synaptic Organization Shapes Place Fields in CA1 Pyramidal Neurons The synaptic mechanisms driving feature selectivity in specific neuron types remains a fundamental and unresolved challenge in neuroscience. In hippocampal CA1 pyramidal neurons (PNs), the development...

New collaborative preprint with Losonczy Lab and Polleux Lab!
How does synaptic organization shape place fields in CA1 Pyramidal Neurons?
We mapped thousands of synapses & showed that clustering of excitatory inputs is key for tuning.
www.biorxiv.org/content/10.1...
#Neuroscience #bioRxiv

Our recent paper on Dendritic ANNs, led by @spiroschav.bsky.social has been featured in Nature Communications Editors' Highlights! Check it out in the AI/Machine Learning and Applied Physics/Mathematics collections: www.nature.com/collections/...

Study shows that dendritic plasticity contributes to the integration of memories Past neuroscience studies suggest that memories of events that occurred at short time intervals from one another are often connected, via a process referred to as memory linking. While memory linking ...

📰Dendrites Press
Excited about our latest research highlighted in@medicalxpress.com.web.brid.gy. Our collaborative work with Alcino Silva at UCLA, led by @meghasehgal.bsky.social sheds light on the mechanisms of memory linking, which remained a mystery for years.
medicalxpress.com/news/2025-03...

Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time - Nature Neuroscience Sehgal et al. show that branch-specific dendritic plasticity mechanisms in the retrosplenial cortex link memories acquired close in time such that, unlike independent memories, linked memories are enc...

New research, in @natureneuro.bsky.social reveals that dendritic plasticity is essential for linking contextual memories!
Dr. George Kastellakis, in Poirazi Lab, @imbb-forth.bsky.social, contributed to this study under the supervision of Dr. @yiotapoirazi.bsky.social.
www.nature.com/articles/s41...

A new, brain-inspired AI technology boosts efficiency and reduces energy consumption | News | Foundation for Research and Technology - Hellas Researchers at the Institute of Molecular Biology and Biotechnology of FORTH have developed a new type of artificial neural network (ANN) that incorporates features of biological dendrites. This innov...

📝In their research published @naturecomms.bsky.social, Dr.P.Poirazi,Research Director @dendritesgr.bsky.social Lab
@imbb-forth.bsky.social & the post doctoral researcher Dr.S. Chavlis,demonstrate how dendritic features in ANNs can significantly improve their efficiency & performance. bit.ly/4aKyC1S

Dendrites endow artificial neural networks with accurate, robust and parameter-efficient learning - Nature Communications Artificial neural networks, central to deep learning, are powerful but energy-consuming and prone to overfitting. The authors propose a network design inspired by biological dendrites, which offe...

Towards a More Sustainable Future for AI:
Led by Dr. Chavlis, our research, published in @naturecomms.bsky.social, demonstrates how incorporating dendritic features into Artificial Neural Networks (ANNs) can significantly improve their efficiency and performance.
www.nature.com/articles/s41...