Laura Wisse's Avatar

Laura Wisse

@lemwisse.bsky.social

Associate professor | Lund University | Neuroimaging | Neurodegenerative diseases | Medial temporal lobe | https://medialtemporallab.com

212 Followers  |  235 Following  |  14 Posts  |  Joined: 19.11.2024  |  2.0797

Latest posts by lemwisse.bsky.social on Bluesky

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Tau, atrophy, and domain‐specific cognitive impairment in typical Alzheimer's disease INTRODUCTION A granular understanding of the mechanisms linking tau pathology to cognitive decline in Alzheimer's disease is crucial. We investigate mediating effects of medial temporal lobe (MTL) a...

🚨This study led by @anikawuestefeld.bsky.social aims to provide a more granular understanding of how tau pathology leads to specific cognitive decline in Alzheimer's disease. 🧠 Out now in Alzheimer’s & Dementia! Read it here: doi.org/10.1002/alz....
πŸ§΅πŸ‘‡

05.08.2025 14:16 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1

Really happy that the final paper of my PhD is out now!
It was great to work on this project with Dave Wolk (@picslupenn.bsky.social) & @lemwisse.bsky.social and all others involved!
See below for more information! πŸ‘‡

05.08.2025 14:24 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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So excited to attend #AAIC25 in person again this year! Looking forward to a week of exciting science to #ENDALZ.

Very proud of my trainees who will be presenting their work - don't forget to tune in!

24.07.2025 10:07 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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This is your quarterly reminder that the hippocampus is a cortical (not subcortical) structure! Nicola Palomero-Gallagher underscored this point during our #OHBM2025 educational course!

24.06.2025 05:37 β€” πŸ‘ 51    πŸ” 7    πŸ’¬ 1    πŸ“Œ 2
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Docent Psychologie De Sectie Cognitieve Psychologie van het Instituut Psychologie van de Faculteit Sociale Wetenschappen heeft een vacature voor Docent Psychologie Dit ga je doen Als docent psychologie ga je onderwijs v...

Come work in my dept! We are hiring a lecturer in psychology (ideally speaking Dutch) @leidenpsychology.bsky.social

www.academictransfer.com/en/jobs/3529...

20.06.2025 11:02 β€” πŸ‘ 11    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
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Very proud of @anikawuestefeld.bsky.social for finishing her PhD thesis on the medial temporal lobe in aging and dementia! Following Swedish tradition, the thesis is now nailed to the wall.... last step before the defense next week. I have no doubt she will nail this too!

13.06.2025 14:24 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Demo of new Deep Learning Segmentation in ITK-SNAP 4.4
YouTube video by ITK-SNAP Demo of new Deep Learning Segmentation in ITK-SNAP 4.4

youtu.be/gpQ19OPUm34

New integration with nnInteractive (github.com/MIC-DKFZ/nnI...) in ITK-SNAP 4.4.0-alpha2 (itksnap.org) lets you turn scribbles into 3D segmentations in seconds. All thanks to an amazing new model from Fabian Isensee and colleagues at @helmholtzimaging.bsky.social!

05.06.2025 22:00 β€” πŸ‘ 4    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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Medial temporal lobe structural changes when Down syndrome and Alzheimer’s disease collide This scientific commentary refers to β€˜Medial temporal lobe atrophy in Down syndrome along the Alzheimer’s disease continuum’ by Buehner et al. (https://doi

Also check out my commentary with @relajoie.bsky.social: shorturl.at/bOTtY

03.06.2025 10:23 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Medial temporal lobe atrophy in Down syndrome along the Alzheimer’s disease continuum Buehner et al. describe progressive structural changes in the medial temporal lobe in association with Alzheimer's disease pathology in 259 adults with Dow

Very important article on Down syndrome and AD by Buehner et al.(shorturl.at/ETFUz) highlighting the non-linear trajectories of structural changes in MTL subregions in patients with Down syndrome & AD and the utility of MTL structural markers for clinical trials and prediction of decline.

03.06.2025 10:23 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! 🧠

πŸ™ I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this ~5min survey: alz.surveymonkey.com/r/923BTQK

28.04.2025 18:26 β€” πŸ‘ 11    πŸ” 8    πŸ’¬ 1    πŸ“Œ 1

Woohoo!!

25.04.2025 09:56 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

🧠 PhD position available!

Study polypathology in the medial temporal lobe at the Paris Brain Institute with @lemwisse.bsky.social , @nvillain-alz.bsky.social and myself.

This exciting project combines neuroimaging, neuropathology and cognition!

Please share widely πŸ™

24.04.2025 07:28 β€” πŸ‘ 6    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

Exciting opportunity for a PhD position at the @institutducerveau.bsky.social on a European collaborative project under the supervision of medial temporal lobe specialists!
Spread the word!

bsky.app/profile/lemw...

23.04.2025 10:26 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Very grateful for the funding of this project provided by @alzheimer-recherche.org!

23.04.2025 07:52 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Nos super offres || PhD - polypathology in the medial temporal lobe

Super excited to announce a PhD position on polypathology in the medial temporal lobe at the Paris Brain Institute together with @nvillain-alz.bsky.social and @robindeflores.bsky.social!

offres.institutducerveau-icm.org/fr/jobs/1935...

Please repost!

23.04.2025 07:16 β€” πŸ‘ 3    πŸ” 5    πŸ’¬ 1    πŸ“Œ 3
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Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness
academic.oup.com/brain/articl...

06.03.2025 19:15 β€” πŸ‘ 535    πŸ” 309    πŸ’¬ 51    πŸ“Œ 104

If judge don’t stop, NIH employees review new/ongoing projects:

Cat 1: solely support DEI activities. CUT

Cat 2: partially support. Renegotiate or CUT

Cat 3: don’t support but some DEI language. Cont./cut language in app/progress reports.

Cat 4: don’t support any. Cont & DEI not in reports.

06.03.2025 06:40 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Medial temporal lobe atrophy patterns in early-versus late-onset amnestic Alzheimer’s disease - Alzheimer's Research & Therapy Background The medial temporal lobe (MTL) is hypothesized to be relatively spared in early-onset Alzheimer’s disease (EOAD). Yet, detailed examination of MTL subfields and drivers of atrophy in amnest...

Excited that is also available in new version of ASHS including not only anterior MTL cortical regions but also the amygdala!
www.nitrc.org/frs/shownote...

The amygdala protocol developed by @anikawuestefeld.bsky.social is described in the supplements of alzres.biomedcentral.com/articles/10....

26.02.2025 08:47 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Developing an anatomically valid segmentation protocol for anterior regions of the medial temporal lobe for neurodegenerative diseases Background The anterior portion of the medial temporal lobe (MTL) is one of the first regions targeted by pathology in sporadic Alzheimer’s disease (AD) and Limbic-predominant Age-related TDP-43 Encep...

Beautiful work by Niyousha Sadeghpour developing a manual segmentation protocol for the anterior MTL cortex, important in AD and LATE! Grounded in a large set of annotated histology sections and postmortem MRI scans, labelled by the late Ricardo Insausti & his team.

www.biorxiv.org/content/10.1...

26.02.2025 08:47 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1

Also big thanks to coauthors @anikawuestefeld.bsky.social @drneurochic.bsky.social and Bill Jagust!

25.02.2025 08:52 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Role of tau versus TDP‐43 pathology on medial temporal lobe atrophy in aging and Alzheimer's disease Hippocampal atrophy on magnetic resonance imaging is an important biomarker in Alzheimer's disease (AD). While hippocampal atrophy was thought to result from tau tangles in AD, different neuropathol...

Lovely collaboration with Renaud La Joie - our review is finally out! Summarizing the role of tau and TDP-43 in medial temporal atrophy in Alzheimer's disease and exploring different hypotheses regarding their potential timing and synergism.

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

24.02.2025 13:35 β€” πŸ‘ 12    πŸ” 5    πŸ’¬ 1    πŸ“Œ 2
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Jobs and vacancies - Faculty of Social Sciences Read this story on the University of Oslo's website.

There are currently three open faculty positions (all levels) in my department (Psychology)
Oslo is a lovely city, modestly sized (600k) but a capital, surrounded by forest and the fjord

We're also a stable democracy with high support of and trust in science

www.sv.uio.no/english/abou...

19.02.2025 14:17 β€” πŸ‘ 171    πŸ” 95    πŸ’¬ 4    πŸ“Œ 8

PA Attorney General: 717-787-3391

10.02.2025 19:40 β€” πŸ‘ 12    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
Brain Connectomics, Pereira's Lab – Joana Pereira's research group Our group works with brain connectivity, biofluid markers and behavioural measures in aging, neurodegenerative and psychiatric disorders.

I am looking for a Postdoc to work in my group at Karolinska Institute in projects that combine brain imaging with machine learning, genetics & proteomics in aging and neurodegenerative diseases. To apply please go to: ki.varbi.com/en/what:job/... (Deadline: 20.Feb.2025) Please retweet. Thanks!

03.02.2025 04:37 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
A group of international early career researchers wearing purple tee shirts and holding cut out signs reading β€œAAIC” and β€œISTAART”

A group of international early career researchers wearing purple tee shirts and holding cut out signs reading β€œAAIC” and β€œISTAART”

Applications are now open for the ISTAART Ambassador Program 2025-26!

This program offers early-career researchers access to #AAIC25, as well as year-round training, networking, and mentoring opportunities.

Apply by Feb 10, 2025, at alz.org/ISTAARTambassadors!

09.01.2025 13:56 β€” πŸ‘ 11    πŸ” 13    πŸ’¬ 0    πŸ“Œ 0
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Associate Senior Lecturer in Medical Radiation Physics with a focus on MR physics Medical radiation physics is a subject area where physics and various radiation applications meet biology and medicine. Our activities include research and teaching in ionizing and non-ionizing radiat

Come work with us! Open tenure-track-style position in MRI physics in Lund, Sweden. lu.varbi.com/en/what:job/...

23.01.2025 15:25 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

** We are hiring ** Associate Prof / Full Prof position in Cognitive Neuroscience. Amazing department, rated top in the UK for research power in Psychology, Psychiatry and Neuroscience. Can hire internationally, so flagging for USA colleagues (all countries welcome). Come join us in London

22.01.2025 22:36 β€” πŸ‘ 45    πŸ” 40    πŸ’¬ 2    πŸ“Œ 1
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ISTAART members! Have you submitted your work to #AAIC25 yet?

Abstract submissions are extended till Jan 31 for members, so submit yours today!

alz.org/AAIC

16.01.2025 15:53 β€” πŸ‘ 17    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
Open competition - LISS DTP

If you know anyone who's looking for a PhD in neurodegenerative diseases with a focus on data science and epidemiology, this scheme looks great. I would be happy to supervise projects in the Global Health Innovation stream.

liss-dtp.ac.uk/applying-to-...

07.01.2025 18:31 β€” πŸ‘ 6    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
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A Pillar of Neuroscience Passes Away. His Legacy Will Live On. - Qhubo Renowned neuroscientist Ricardo Insausti Serrano has passed away on December 26, leaving an indelible mark in the field of neurodegenerative research, particularly Alzheimer’s. This loss is felt deepl...

Saddened by the news of Ricardo Insausti passing away. I had the privilege of collaborating with him for almost a decade and learned a tremendous amount from him. He was a world-leading expert on MTL anatomy, a wonderful mentor and person. I will miss him dearly.

www.qhubo.com.ni/news2/a-pill...

07.01.2025 13:43 β€” πŸ‘ 16    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1

@lemwisse is following 20 prominent accounts