#HLH, #Trisomy21, immune dysregulation ...
Case conf webinar featuring:
*** Joaquin Espinosa (espinosalab.org) ***
Thursday 13 November, 11AM ET
Register at
us02web.zoom.us/webinar/regi...
@clinimmsoc.bsky.social
@cannalab.bsky.social
Auto- & Hyper-inflammation | MAS HLH | IL-18 | It's all Immune Dysregulation | Gettinβ down wit OPD | β€οΈer of puns | π² evangelist | opinions my own labcanna.org
#HLH, #Trisomy21, immune dysregulation ...
Case conf webinar featuring:
*** Joaquin Espinosa (espinosalab.org) ***
Thursday 13 November, 11AM ET
Register at
us02web.zoom.us/webinar/regi...
@clinimmsoc.bsky.social
Quote graphic that reads "We are gravely concerned that American people will needlessly suffer and die as a result of policies that turn away from sound interventions. After careful consideration, we insist on Kennedyβs resignation to restore the integrity, credibility and science-driven mission of HHS and all its agencies." with AAI logo
We have joined @idsainfo.bsky.social, @asm.org, and 19 other medical, scientific, public health and patient organizations, in calling for the resignation of HHS Secretary Robert F. Kennedy Jr., to ensure the health of the American people.
Read the statement in full: news.aai.org/2025/09/04/j...
Too bad that the timelapse we made of an activated CTL (green, Ca++ flux) and contracting BMDC (red/PI) was too low-res for the cover.
31.07.2025 21:30 β π 0 π 0 π¬ 0 π 0Thx @bloodjournals.hematology.org editors for highlighting our work (led by AFKamenetskii) on the
HLH Immune Synapse
doi.org/10.1182/bloo...
Thx also to Drs. Machowicz & La Rosee for their editorial
"HLH: it is all about communication" doi.org/10.1182/bloo...
When βowning the libsβ means turning your back on the most successful humanitarian act ever (vaccination), Iβm grateful for an AAP with the courage and knowledge to step up.
25.06.2025 23:07 β π 0 π 0 π¬ 0 π 0Fun writing "Insights from the 2024 ACR/PRES Peds Basic/Translational YIR" with the talented Dr. Jessica Turnier @umich.edu.
My 1st time citing @glaucomflecken.bsky.social ... so far.
link.springer.com/article/10.1...
Drs. Manson & Tattersall have led a UK-wide effort to bring consistent, excellent #HLH care to their institutions & the broader @england.nhs.uk ... & tracking their outcomes.
Please register: us02web.zoom.us/webinar/regi...
Histiocyte Society #HLH Webinar
"Multi-disciplinary Approach to Managing HLH"
Headlined by @racheltattersall.bsky.social and Jessica Manson, @ucl.ac.uk who've really brought HLH excellences to @england.nhs.uk
July 24th, 11AM NY/8AM SF/4PM UK/5PM CET
Details and link are forthcoming
"Modeling the #HLH immune synapse uncovers critical roles for IS termination, cytokine intensity, and target cell death"
We're pretty excited about this one.
doi.org/10.1182/bloo...
It takes a special talent to observe the phenotype of an ETS1 super-enhancer deletion and see into the evolution of paralogous transcription factors.
Holy π€―, @vahedilab.bsky.social!
When you love bicycles AND immunology, you gotta share it with like-minded friends. Beautiful AM ride through Belmont Plateau here in Philly with Drs. Hoffman & Platt. #CIS2025.
03.05.2025 14:34 β π 5 π 0 π¬ 1 π 0@autoinflammatory.bsky.social, @rashmi.bsky.social,
If you have a Still's problem,
if no one else can help,
and if you can find a lab to run it
maybe you can test for ...
A #STAT1 #STAT3 master class from Alejandro Villarino
@upenn.edu IGG.
Crazy for Americans to be talking about IL-18 in Japan, but luckily @grantschulert.bsky.social already warmed up the crowd.
26.04.2025 07:21 β π 5 π 1 π¬ 0 π 0Next: Dr. Nishikomori (Kurume) - stability of somatic NLRP3 VAF in early vs. late-onset somatic NLRP3, capitalizing on π―π΅ tradition of keeping dried umbilic cord!!
Why in somatic CAPS does phenotype match genotype, not VAF? NOMID variant in 5% = NOMID, not FCAS?!
@autoinflammatory.bsky.social
Having a great time at Japan College of Rheumatology meeting, Fukuoka.
Most recent head-explosion, new story from the JJ Chae wing of the Kastner machine: Cofilin-1 senses ROS by auto-inhibiting under oxidative conditions and releasing NLRP3.
This May, please consider bike commuting. Please also consider supporting @chopresearch.bsky.social
chop.donordrive.com/index.cfm?fu...
Power-plays aside, this (science.org/content/arti...) is short-sighted
The backlash is building. It will insist on protecting NIH from future reckless sabotage. It will make NIH even more resistant to reform.
Playing an βice breakerβ game β¦ the best possible prompt.
26.03.2025 15:38 β π 0 π 0 π¬ 0 π 0