Espinosa Lab
#HLH, #Trisomy21, immune dysregulation ...
Case conf webinar featuring:
*** Joaquin Espinosa (espinosalab.org) ***
Thursday 13 November, 11AM ET
Register at
us02web.zoom.us/webinar/regi...
@clinimmsoc.bsky.social
16.10.2025 23:02 β π 2 π 0 π¬ 0 π 0
Quote graphic that reads "We are gravely concerned that American people will needlessly suffer and die as a result of policies that turn away from sound interventions. After careful consideration, we insist on Kennedyβs resignation to restore the integrity, credibility and science-driven mission of HHS and all its agencies." with AAI logo
We have joined @idsainfo.bsky.social, @asm.org, and 19 other medical, scientific, public health and patient organizations, in calling for the resignation of HHS Secretary Robert F. Kennedy Jr., to ensure the health of the American people.
Read the statement in full: news.aai.org/2025/09/04/j...
04.09.2025 16:45 β π 15 π 3 π¬ 0 π 1
Too bad that the timelapse we made of an activated CTL (green, Ca++ flux) and contracting BMDC (red/PI) was too low-res for the cover.
31.07.2025 21:30 β π 0 π 0 π¬ 0 π 0
Thx @bloodjournals.hematology.org editors for highlighting our work (led by AFKamenetskii) on the
HLH Immune Synapse
doi.org/10.1182/bloo...
Thx also to Drs. Machowicz & La Rosee for their editorial
"HLH: it is all about communication" doi.org/10.1182/bloo...
31.07.2025 21:30 β π 2 π 0 π¬ 2 π 0
When βowning the libsβ means turning your back on the most successful humanitarian act ever (vaccination), Iβm grateful for an AAP with the courage and knowledge to step up.
25.06.2025 23:07 β π 0 π 0 π¬ 0 π 0
Drs. Manson & Tattersall have led a UK-wide effort to bring consistent, excellent #HLH care to their institutions & the broader @england.nhs.uk ... & tracking their outcomes.
Please register: us02web.zoom.us/webinar/regi...
20.05.2025 21:55 β π 1 π 0 π¬ 0 π 0
Histiocyte Society #HLH Webinar
"Multi-disciplinary Approach to Managing HLH"
Headlined by @racheltattersall.bsky.social and Jessica Manson, @ucl.ac.uk who've really brought HLH excellences to @england.nhs.uk
July 24th, 11AM NY/8AM SF/4PM UK/5PM CET
Details and link are forthcoming
14.05.2025 14:15 β π 5 π 5 π¬ 0 π 1
"Modeling the #HLH immune synapse uncovers critical roles for IS termination, cytokine intensity, and target cell death"
We're pretty excited about this one.
doi.org/10.1182/bloo...
13.05.2025 21:54 β π 3 π 3 π¬ 0 π 0
It takes a special talent to observe the phenotype of an ETS1 super-enhancer deletion and see into the evolution of paralogous transcription factors.
Holy π€―, @vahedilab.bsky.social!
06.05.2025 21:36 β π 6 π 1 π¬ 1 π 0
When you love bicycles AND immunology, you gotta share it with like-minded friends. Beautiful AM ride through Belmont Plateau here in Philly with Drs. Hoffman & Platt. #CIS2025.
03.05.2025 14:34 β π 5 π 0 π¬ 1 π 0
@autoinflammatory.bsky.social, @rashmi.bsky.social,
If you have a Still's problem,
if no one else can help,
and if you can find a lab to run it
maybe you can test for ...
01.05.2025 14:35 β π 2 π 0 π¬ 0 π 0
A #STAT1 #STAT3 master class from Alejandro Villarino
@upenn.edu IGG.
29.04.2025 20:48 β π 1 π 0 π¬ 0 π 0
Crazy for Americans to be talking about IL-18 in Japan, but luckily @grantschulert.bsky.social already warmed up the crowd.
26.04.2025 07:21 β π 5 π 1 π¬ 0 π 0
Next: Dr. Nishikomori (Kurume) - stability of somatic NLRP3 VAF in early vs. late-onset somatic NLRP3, capitalizing on π―π΅ tradition of keeping dried umbilic cord!!
Why in somatic CAPS does phenotype match genotype, not VAF? NOMID variant in 5% = NOMID, not FCAS?!
@autoinflammatory.bsky.social
26.04.2025 06:28 β π 1 π 0 π¬ 0 π 0
Having a great time at Japan College of Rheumatology meeting, Fukuoka.
Most recent head-explosion, new story from the JJ Chae wing of the Kastner machine: Cofilin-1 senses ROS by auto-inhibiting under oxidative conditions and releasing NLRP3.
26.04.2025 06:01 β π 3 π 1 π¬ 1 π 0
Trump administration purges U.S. health agency leaders
Reassignment letters come as reductions in force begin at NIH, FDA, and CDC
Power-plays aside, this (science.org/content/arti...) is short-sighted
The backlash is building. It will insist on protecting NIH from future reckless sabotage. It will make NIH even more resistant to reform.
01.04.2025 18:54 β π 0 π 0 π¬ 0 π 0
Playing an βice breakerβ game β¦ the best possible prompt.
26.03.2025 15:38 β π 0 π 0 π¬ 0 π 0
Decoding how the gut thinks π¦ πͺ±π§ πͺ
Neuroscientist with interests in
#EnergyMetabolism #EntericNeurons #Fats
@crick.ac.uk @institutducerveau.bsky.social
Immunologist - neutrophils, macrophages, immunometabolism
PhD student with Thomas Weichhart @ Medical University of Vienna | MD by training
MD/PHD student studying defective B cell tolerance in SLEπ©πΎβπ¬πΊ at SUNY Downstate #medsky
Carnegie Mellon'18πβπ¦Ί Aspiring #obgynsky #physicanscientist π€°
RYT-200π§π½ββοΈ
Our mission is to apply bold, collaborative, translational science to advance our mechanistic understanding of human autoimmunity. Proudly part of the @coltonconsortium.bsky.socialβ¬.
Learn more: www.med.upenn.edu/penncoltoncenterautoimmunity
Transforming routine immune profiling to power the future of medicine. I3H builds on Penn Medicineβs pioneering legacy in immunology to advance discovery across disciplines. Perelman School of Medicine, University of Pennsylvania
π www.med.upenn.edu/i3h
Dr. Stuart Turvey and the Turvey lab are committed to improving child health through research. Our research transforms lives. There is urgency to what we do! We are based at UBC and BC Children's Hospital, Vancouver, Canada. π¨π¦ bcchr.ca/turveylab
Translational research @ucl.ac.uk focusing on lipid metabolism defects in autoimmunity. Special interest in autoimmune rheumatic disease, haemophagocytic lymphohistiocytosis (HLH), cardiovascular risk and immunogenicity
The Space Telescope Science Institute is the Science Operations Center for Webb, Hubble, and the upcoming Roman space telescopes, & Mission Operations Center for Webb. We help humanity explore the universe with advanced space telescopes and data archive.
Penn Epigenetics Institute at The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
Associate Professor at the University of Lausanne
Researcher
Proteostasis; Autoinflammation; Inflammasomes
MD, PhD, professor of pediatric rheumatology & immunology
Infectious disease MD. Medical Microbiologist
Clinician-Scientist (Inborn Errors of Immunity)
Clinical section head: ID-Heme/Onc/Transplant
Inaugural Fellow of CIS
Fellow of IDSA
Member, Henry Kunkel Society
Science & sarcasm..not necessarily in that order
Armenian American Scientist studies immune responses to #microbes, #tissueinjury, & earliest stages of #cancer.
Professor, Head of Biomedical Research Lab
https://www.theblanderlab.org
#macrophage #Dendriticcell #inflammasome #celldeath #Tcell
π΄σ §σ ’σ ³σ £σ ΄σ Ώ Cytokines Parasites
Interested in immunology, metabolism, and aging.
George and Sandra K. Schussel Associate Professor. Associate Chair, Program in Virology. Interested in Epstein-Barr virus, B cells, cancer, lymphoma, gastric cancer, nasopharyngealcarcinoma, immunometabolism, CRISPR, multiple sclerosis
Principal Investigator of the Spatial Immunology Unit | Independent Research Scholar | NIH/NIAID Intramural Research Program
Spatially mapping the immune ecosystem of infection and inflammation
(Views are my own)
