Adam Marblestone

Universities should help shape the vision for new NSF Tech Labs At a time when universities are already facing intense pressure to re-envision their role in the S&T ecosystem, we encourage NSF to ensure that the ambitious research acceleration remains compatible w...

fas.org/publication/...

NSF Wants To Supercharge FROs. We Spoke With the Scientists Who Proposed Them. We recently spoke with Adam Marblestone and Sam Rodriques, former FAS fellows who developed the idea for FROs and advocated for their use in a 2020 policy memo.

To mark the occasion, FAS CEO Daniel Correa spoke with @sgrodriques.bsky.social and @adammarblestone.bsky.social about how best to run a Tech Lab/FRO-style org, what they've learned, and the role federal funding can play:
fas.org/publication/...

Opinion | Science Funding Goes Beyond the Universities A new NSF initiative will support teams of researchers, a departure from the traditional practice of giving grants to individual professors.

www.wsj.com/opinion/scie...

NSF Wants To Supercharge FROs. We Spoke With the Scientists Who Proposed Them. We recently spoke with Adam Marblestone and Sam Rodriques, former FAS fellows who developed the idea for FROs and advocated for their use in a 2020 policy memo.

fas.org/publication/...

If you've been interested in FROs, you'll want to see this from NSF:
sam.gov/opp/7332ade9...
"sustained... support to... independent organizational structures operating outside of existing academic, start-up, and industry constraints... a dedicated, full-time team... operational independence..."

A genetic platform for a biocementation bacterium https://www.biorxiv.org/content/10.64898/2025.12.05.692644v1

[C]Worthy Secures Multi-Year Support From ORCA and the Patrick J. McGovern Foundation to Scale Open-Source Marine Carbon-Removal Tools — [C]Worthy New multi‑year awards affirm the need for infrastructure built through [C]Worthy’s approach of marrying open-source science and practical tools for industry use.

[C]Worthy has secured multi-year support from ORCA and the Patrick J. McGovern Foundation to scale open, trusted science tools for ocean-based carbon removal.

We can’t scale what we can’t measure—this funding accelerates our MRV models + datasets.

Full announcement: www.cworthy.org/media/cworth...

A global screen for magnetically induced neuronal activity in the pigeon brain How animals detect the Earth’s magnetic field remains a mystery in sensory biology. Despite extensive behavioral evidence, the neural circuitry and molecular mechanisms responsible for magnetic sensin...

A global screen for magnetically induced neuronal activity in the pigeon brain www.science.org/doi/10.1126/... - so cool! 🐦🧠

Active learning guides automated discovery of DNA delivery via electroporation for non-model microbes Delivery of recombinant DNA is foundational for understanding and engineering a target organism. Electroporation can be applied to any cell type, yet identification of a working protocol for new organ...

Have a look if you are interested in how the team at @cultivarium.bsky.social is finding electroporation protocols for new microbes: both screening lots of conditions on a custom built electroporator concurrently, and cyclical iteration using bayesian optimization

www.biorxiv.org/content/10.1...

Putting Pharmome Data in Researchers' Hands : EvE Bio We've been busy at EvE Bio these last two years establishing the largest available pharmome mapping dataset. Now it’s making its way into the world to drive real discoveries.

Announced today: @evebio.bsky.social's pharmome-mapping dataset - the largest public map of how compounds do or don’t touch druggable targets - is now live on DrugBank's knowledgebase and available programmatically + interactively on Hugging Face, @hf.co.

Learn more: evebio.org/pharmome-dat...

a poster titled a synaptic locus of song learning

Poster now til 12 pm, come check it out at V6! #SfN25

Is there an academic/industry divide in attitudes about using AI to support discovery? I noticed this post has 3.6k likes on X but only 6 likes on Bluesky. It deserves more attention here!

Programme development | Trust Everything, Everywhere We are in the process of building a multi-year R&D programme within this space. Our programmes are designed to advance complex, large-scale ideas that require coordinated investment and management acr...

As AI collapses coordination costs, our new thesis - Scaling Trust - explores how scalable trust infrastructure could usher in a world of many AI agents, capable of mobilising, negotiating, and verifying on our behalf across digital + physical spaces ↓
link.aria.org.uk/ST-thesis-BS

Gotta get the mouse connectome

It is actually an incredibly frustrating time to be a theoretical neuroscientist right now imo, for this reason

cool! tools to making it easier to work with 𝘐𝘥𝘦𝘰𝘯𝘦𝘭𝘭𝘢 𝘴𝘢𝘬𝘢𝘪𝘦𝘯𝘴𝘪𝘴 (now 𝘗𝘪𝘴𝘤𝘪𝘯𝘪𝘣𝘢𝘤𝘵𝘦𝘳 𝘴𝘢𝘬𝘢𝘪𝘦𝘯𝘴𝘪𝘴) for PET degradation

#MicroSky

Cool work from our neighbors at @cultivarium.bsky.social using components from the POSSUM Toolkit! What will they (or you!) find next?
Check out the toolkit here: www.addgene.org/kits/cultiva...

Very happy to share our recent work @cultivarium.bsky.social on genetic tools for Ideonella sakaiensis, a (Betaproteo-)bacterium that degrades PET plastic.

We identified a plasmid vector for the strain and generated a large RB-TnSeq library, screening for genes impacting plastic degradation.

The songbird basal ganglia connectome The basal ganglia (BG) play an essential role in shaping vertebrate behavior, ranging from motor learning to emotions, but comprehensive maps of their canonical synaptic architecture are missing. In m...

I am happy to share that the main story of my PhD is now available as a preprint! www.biorxiv.org/content/10.1...

We analyses over 8500 neurons in a songbird basal ganglia dataset.

To explore this and two other stories more interactively, also check out our website!
www.songbird-connectomics.org

Our new preprint outlining how to make 1000-plex mass tags!

How to design 1000-plex mass tags using the differential mass defect Multiplexing samples in mass spectrometry-based proteomics has long been accomplished by isotopologues of small molecules. These chemically-identical "mass tags" conjugate to peptides to encode sample...

A bit dense, but the important message is dead simple:

We got to cite the E = mc² paper!

Kidding :)

The important part is that combinations of isotopes unlock 100-1000x gains in protein measurement speed.

Here's how: www.biorxiv.org/content/10.1...

#TeamMassSpec #Proteomics 🧪

Microbe-Mineral Atlas Engineering The Barstow lab at Cornell University is looking for a new postdoc for 2026 and beyond to help us with the next phase of our Microbe-Mineral Atlas project. We plan on going from basic scientific disco...

We’re starting to look for postdocs for 2026 and beyond. Nothing official yet, but if you want to use your synbio skills and the growing Microbe-Mineral Atlas to build cutting-edge biomining technologies read more below:

docs.google.com/document/d/1...

Thanks for contributing your expertise!!

I got to editing a few clips to show how I make plant tissue culture leaf disks from leaves obtained in open air. Uploaded for your consideration to the PRISM collection. Enjoyyyyy.

prism.cultivarium.org/protocols/20...

What is the future missing?

convergentresearch.org

Semble | A social knowledge network for researchers Follow your peers' research trails. Surface and discover new connections. Built on ATProto so you own your data.

8/ With semble.so and @cosmik.network we are aiming squarely at the CI space, but it is ultimately an ecosystem effort, so we’re excited to be building with the vibrant ATProto community ✨

Excited to try this! The waiting list makes me even more curious

Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...

We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10

💡Did you know you can run #LeanLang in your browser without installing anything? The Lean Playground provides a full environment for experimentation, learning, and for sharing code snippets with others.

Try it out! live.lean-lang.org

Wait uh, what?? 🤩