Rice Neuroengineering Initiative

Big news coming out of Rice University. The Rice Brain Institute has launched to foster new collaborative research on our campus! A new era of research in brain health that links Biosciences, Engineering, Social Science, with Government Policy.
bit.ly/4oAE6C0

Is Psychiatry Ready for Closed-Loop Invasive Neuromodulation? This Viewpoint discusses closed-loop invasive neuromodulation treatment for neurological or psychiatric disorders resistant to conventional therapy.

Read more (subscription required) jamanetwork.com/journals/jam...

In this month's @jamapsychiatry.com Rice NEI faculty members @sameershethmd.bsky.social and Wayne Goodman examine the recent approval of adaptive #DBS for Parkinson's and whether closed-loop neuromodulation strategies are ready for clinical practice in neurological and psychiatric disorders.

Is Psychiatry Ready for Closed-Loop Invasive Neuromodulation? This Viewpoint discusses closed-loop invasive neuromodulation treatment for neurological or psychiatric disorders resistant to conventional therapy.

Read more (subsription required) jamanetwork.com/journals/jam...

Cool work coming out of Mechanical Engineering here at Rice that could advance medical engineering news.rice.edu/news/2025/ri...

This work provides insights into CSF flow patterns that may play a role in brain waste clearance and neurodegenerative disease mechanisms as we age, paving the way for improved diagnostic and therapeutic strategies.
Read more: pubs.rsna.org/doi/full/10....

Researchers from the joint @riceneuro.bsky.social and Houston Methodist Center for Neural Systems Restoration recently developed an approach to noninvasively measure CSF dynamics along blood vessels using advanced MRI and image processing techniques.

Traditional implantable devices with more electrodes also entail more wires and invasive surgeries. A new system from Robinson Lab offers a distributed network where implants are individually programmable and respond to unique digital instructions from a single transmitter.
bit.ly/4pTHIAS

A wonderful write-up in the Fall Rice Research Review outlining a few of our initiatives' ongoing projects in the areas of neural recording, synthetic serum biomarkers, and other brain research from the NEI and across campus.

Read more: bit.ly/4gMWrsQ

Marcia O’Malley and Jeffrey Tabor elected Fellows of the International Academy of Medical and Biological Engineering | George R. Brown School of Engineering | Rice University

Congratulations to Dr. Marcia O'Malley on this lifetime achievement!

engineering.rice.edu/news/marcia-...

This week's Engineering Minds Seminar welcomes Dr. Nanshu Lu from the @cockrellschool.bsky.social . Dr. Lu will present her lab's work developing a breakthrough e-tattoo technology that leverages automated, on-scalp non-contact printing of PEDOT: PSS-based conductive inks.

Our seminar speaker tomorrow, Dr. Seth Hays from UTDallas Bioengineering, will talk about his work with closed-loop #vagus nerve stimulation and discuss the ongoing efforts to develop and optimize a next-generation #CLV system.

Tomorrow, Dr. Bozhi Tian will discuss how his lab is expanding the frontier of electrophysiological modulation and biosensing. We look forward to his visit and discussions with our faculty and students!

Congratulations @riceneuro.bsky.social member Jessica Butts, who was funded by @apdaparkinsons.bsky.social to use
a new model that identifies and characterizes neurons in a part of the brainstem vulnerable to PD progression called the pedunculopontine tegmental nucleus (PPTg).
More: bit.ly/488vXjf

More funding news last month includes a collaborative grant between Chong Xie and Lan Luan from @riceneuro.bsky.social and Samuel Pfaff from @salkinstitute.bsky.social on a $750K grant, "Recording Spinal Neural Activity Across Genetic Classes During Hindlimb Motor Behaviors." 🎉

Congratulations @nicoleprovenza.bsky.social from
@bcmneurosurgery.bsky.social and @riceneuro.bsky.social
who is the recipient of a $3.7m R01 award from NIH/NIMH for her project, "Neurophysiological investigation of the approach-avoidance axis in OCD: applications to neuromodulation."🎉

@riceneuro.bsky.social researcher Jacob Robinson @jacobrobinson.bsky.social and his team are developing next-gen wireless miniature bioelectric implants that are opening doors to new treatments for a multitude of chronic conditions. Read more about their recently published work here: bit.ly/45VfTi5

Temporal coding carries more stable cortical visual representations than firing rate over time - Nature Communications Whether temporal code and rate code have different rates of representational drift over extended periods is not fully understood. Using ultraflexible electrodes, here authors show that temporal codes ...

Understanding visual representations and their longitudinal stability requires neuronal recording at multiple scales. Results published in Nature Communications indicate that temporal coding may be essential in ensuring consistent sensory experiences over time. Read more: bit.ly/3HPe7aq

Material considerations for delivering therapeutics across the blood–brain barrier Therapeutic drug delivery across the blood–brain barrier (BBB) has been a challenging feat for centuries. The intricate nature of the BBB is protected by multip

@riceneuro.bsky.social Researchers Christina Tringides and Ava Zoba have published a recent review in APL Materials discussing materials advances for therapies that are trying to address the complex challenges presented by the blood-brain barrier. Read more: pubs.aip.org/aip/apm/arti...

@riceneuro.bsky.social will again host a Neuro section at #GCURS 2025 here at Rice University. Undergraduate research in all fields of neuroengineering and neuroscience are welcome to apply. Christina Tringides, Scott Keene, David Lipshutz, Nishal Shah will be our 2025 faculty mentors.

Towards precise synthetic neural codes: high-dimensional stimulation with flexible electrodes - npj Flexible Electronics npj Flexible Electronics - Towards precise synthetic neural codes: high-dimensional stimulation with flexible electrodes

A new npj Flexible Electronics Perspective is out this month from Luan and Xie Labs at @riceneuro.bsky.social. It explores high-dimensional neural stimulation using flexible microelectrode arrays, supported by cortical simulations, to guide next-gen brain-machine interfaces.

bit.ly/3U9wlWH

New and junior researchers at Rice University and TX Medical Center affiliates are invited to register for our Fall NeuroNetworking event next month! It is a great opportunity to make new contacts in the fields of brain research and pitch your own lab's interests.

Unsupervised learning of temporal regularities in visual cortical populations - Nature Communications How the brain extracts and reproduces temporal regularities from incoming sensory information is poorly understood. Here, the authors discover the ability of neural populations in the primary visual c...

Read more: www.nature.com/articles/s41...

@riceneuro.bsky.social Researcher Valentin Dragoi and his team found that visual cortex neurons can learn and replay complex timing patterns after repeated light stimulation, providing clues to how our brains extract and reproduce temporal regularities from a wide range of sensory inputs.

A recent study out in @biorxiv-neursci.bsky.social from @jerzyszablowski.bsky.social lab builds on their RMA platform as a cost-efficient, noninvasive tool that, "enables sensitive, multiplexed, and repeatable measurements of gene expression in the brain with a blood test."

More: bit.ly/3ZygaW9

O’Malley named a winner of the 11th Nagamori Award | George R. Brown School of Engineering | Rice University

🎉An incredible honor that acknowledges the stellar work that Dr. Marcia O'Malley and the generations of MAHI lab students have contributed to this field. Congratulations! 🎉

engineering.rice.edu/news/omalley...

Pseudo-linear summation explains neural geometry of multi-finger movements in human premotor cortex - Nature Communications Here, the authors show that Intracortical recordings in human motor cortex during attempted multi-finger movements reveal a largely linear code with two violations: magnitude normalization and greater...

By recording motor cortical activity, researchers from @riceneuro.bsky.social, @stanfordbrain.bsky.social , and other key institutes found that multi-finger movements are represented in the brain using a pseudo-linear summation of individual finger movements.

Read more: go.nature.com/4kUVuzz

Notch signaling in neurogenesis Summary: This Review explores how Notch signaling regulates mammalian neurogenesis through proneural gene regulation, signaling pathway crosstalk and adult neural stem cell maintenance, highlighting e...

The mechanisms of this pathway are explored from embryonic development through therapeutic potentials for the adult brain. Emerging technologies that measure Notch dynamics are explored, and knowledge gaps are identified. Read more: bit.ly/4mAAShT

A new review paper this week in Development @biologists.bsky.social from @riceneuro.bsky.social Butts Lab, explores the importance of the Notch signaling pathway in neurogenesis. (more)

As part of Brain Tumor Awareness Month, "Meeting of the Minds" is focusing on advancements in brain cancer research, showcasing the many promises that are on the horizon @mdanderson.bsky.social, @riceneuro.bsky.social, and @uthealthhouston.bsky.social. Register here: bit.ly/43t5Pgm #GrayMay