Kasper D Hansen

The ultimate goal of wellness consumerism is to shift all responsibility to the individual health consumer who then gets the "freedom" of navigating an unregulated snake oil market.

How about porting Linux to Rust?

YouTube video by Bruce Springsteen Bruce Springsteen - Streets Of Minneapolis (Official Audio)

I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.

Stay free

I have not tested it. I strongly think action=error should be default.

Glad to share our benchmark study in Genome Biology on highly variable gene (HVG) selection methods for single-cell RNA-seq. We show that a hybrid strategy performs best, now implemented in the mixhvg R package. rdcu.be/eUfjt

We Let AI Run Our Office Vending Machine. It Lost Hundreds of Dollars. An AI agent ran a snack operation in the WSJ newsroom. It gave away a free PlayStation, ordered a live fish—and taught us lessons about the future of AI.

Gift link, probably the funniest thing the Wall Street Journal has done this year.

His lab was humming with discovery. After one year under Trump, it’s almost silent John Quackenbush built a lab that is at the forefront of human genetics research and bioinformatics. Trump administration cuts have put it in danger of collapse.

This is shocking stuff. John Quackenbush has been brilliant since forever. www.statnews.com/2025/12/05/r...

This is real x.com/grok/status/.... Yangtze record swim times but in LLM form

Oops. Ooooooooooooops.

I do hope that nobody has been given or denied a job/promotion based on their SpringerNature citation counts in the past 15 years.

arxiv.org/pdf/2511.01675

h/t @nathlarigaldie.bsky.social

Will definitely include this example in my next talk on how to name files!

✅ Full marks for "make it easy to guess what the heck something is, based on it name".

Bioconductor - Bioconductor 3.22 Released The Bioconductor project aims to develop and share open source software for precise and repeatable analysis of biological data. We foster an inclusive and collaborative community of developers and…

🚀 Bioconductor 3.22 is released!

Thanks to all developers and community members for contributing to the project!

🔗 Please see the full release announcement here: bioconductor.org/news/bioc_3_...

Lieber Institute For Brain Development - Staff Scientist I, Translational Neuroscience A little about us:The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with develop...

We are hiring for a PhD-level Staff Scientist to join our teams in the Translational Neuroscience Division @lieberinstitute.bsky.social. This is an exciting opportunity to work at the intersection of human 🧠 neuroanatomy and molecular neuroscience

recruiting.paylocity.com/recruiting/j...

Yes, that is weird. I for one would rank NAR above Nature Communications if we just focus on journal name.

a close up of a young man 's face with headphones on . ALT: a close up of a young man 's face with headphones on .

This 1980s anti-drug ad, but about screen time

Today at #ASHG25 I will talk about the work of a talented graduate student Dev Raj Bhattarai on cell type-specific isoform expression in Alzheimer's disease at the @nanoporetech.com Education Session (12pm Rm 153). Dev will also present his work today at poster 9228T.

Today at #ASHG2025 Adam Davidovich will talk about our work on inheritance of DNA methylation patterns in mice with some interesting biology, including (to our knowledge) the first paramutation naturally occurring in mammals.

Room 210C at 11am.

I’m at #ashg2025 for a few days. Reach out if you want to chat.

It’s the time of the year where 98% of my feed will become posts from @michaelhoffman.bsky.social on ASHG

Illustration of Burrows-Wheeler Transform and many auxiliary structures from the input string how$now$brown$cow$#

New tool "bwt-svg" for making illustrations of the BWT and the many auxiliary arrays and other structures related to it. Pyodide-based no-installation-necessary interface here: benlangmead.github.io/bwt-svg/. (H/t to @robert.bio for pointing me to pyodide!) Full repo: github.com/benlangmead/....

Identification of de novo variants from parent-proband duos via long-read sequencing While de novo variants cause many Mendelian disorders, their detection currently requires sequencing of the proband and both biological parents. This is not feasible when only one parent is available,...

Looking forward to presenting duoNovo at ASHG this week.

We use long-read sequencing to detect de novo variants without having to sequence both parents. It's conceptually straightforward, and performs very accurately among variants likely to be clinically relevant.

www.medrxiv.org/content/10.1...

Screenshot one of two of blog post at https://dirk.eddelbuettel.com/blog/2025/10/10#rcpparmadillo_15_transition_office_hours detailing offer of office hours to help with CRAN deadlines for packages depending on RcppArmadillo

Screenshot two of two of blog post at https://dirk.eddelbuettel.com/blog/2025/10/10#rcpparmadillo_15_transition_office_hours detailing offer of office hours to help with CRAN deadlines for packages depending on RcppArmadillo

RcppArmadillo 15 CRAN Transition: Offering Office Hours

Offering office hours to help in updating #rstats CRAN packages to RcppArmadillo 15.0.2 given CRAN 'Deadlines' for a number of the reverse-dependency packages. Details and booking link at blog post.

dirk.eddelbuettel.com/blog/2025/10...

Amazing opportunity for help if you're using RcppArmadillo in a CRAN package.

Thanks for posting. This was an amazing read.

This is an important limitation and something we should absolutely work on solving.

I enjoyed reading the Introduction.

Despite the fact that the cover features neither a dragon, nor a spaceship, I have ordered a copy.

Books And Their Covers - Penny Arcade Videogaming-related online strip by Mike Krahulik and Jerry Holkins. Includes news and commentary.

How can we know if it is worth reading without seeing the cover? I hope it has either a dragon or a space ship.

www.penny-arcade.com/comic/2022/0...

This is a masterpiece. Simply excellent
www.instagram.com/reel/DMVGMIC...

Didn’t want to believe this was true. It’s true.

Higher eQTL power reveals signals that boost GWAS colocalization Expression quantitative trait locus (eQTL) studies in human cohorts typically detect at least one regulatory signal per gene, and have been proposed as a way to explain mechanisms of genetic liability...

Good discussion & study-design recommendations in this new preprint by @mikelove.bsky.social @klmohlke.bsky.social & colleagues:
Higher eQTL power reveals signals that boost GWAS colocalization 🧪🧬

www.biorxiv.org/content/10.1...

It all depends on how many times a piece of code is run. Yes, for highly user workflows, it makes a lot of sense to optimize. But that is not all code.