Jürgen Kuball's Avatar

Jürgen Kuball

@jkuball.bsky.social

Chair of the Department of Hematology UMC Utrecht, NL, and Principle investigator interested in biology of gdT cells and allogeneic stem cell transplantation.

345 Followers  |  410 Following  |  15 Posts  |  Joined: 12.02.2024  |  1.6315

Latest posts by jkuball.bsky.social on Bluesky

Two main reasons: (1) Extracting γδTCRs and engineering them into other cell types creates versatile tools to target diverse cancers; (2) γδT cells have distinct homing and functional properties that can complement the arsenal of conventional αβ T cells.

24.07.2025 12:49 — 👍 0    🔁 0    💬 0    📌 0
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Disrupting the balance between activating and inhibitory receptors of γδT cells for effective cancer immunotherapy Nature Reviews Cancer - In this Review, Beringer and colleagues highlight how future strategies for developing immunotherapies using γδT cells and their receptors will depend on creating...

www.nature.com/articles/s41...

@jkuball.bsky.social @sotnom.bsky.social @lydialynch.bsky.social @labminguet.bsky.social

04.06.2025 16:47 — 👍 11    🔁 4    💬 0    📌 0
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Disrupting the balance between activating and inhibitory receptors of γδT cells for effective cancer immunotherapy Nature Reviews Cancer - In this Review, Beringer and colleagues highlight how future strategies for developing immunotherapies using γδT cells and their receptors will depend on creating...

🧬 Proud to share our latest review in Nature Cancer Reviews! Our article, "Disrupting the balance between activating and inhibitory receptors of γδT cells for effective cancer immunotherapy", highlights a powerful but often overlooked player in the immunotherapy landscape.

rdcu.be/eo4RX

02.06.2025 13:58 — 👍 7    🔁 0    💬 2    📌 0
The EU CAR-T Handbook

Major achievement of the GoCART Coalition and all authors to release the 2025 edition of the EU CAR-T handbook at #EBMT25. Thx to my co-editors, all authors, EBMT and EHA to support this amazing project that will allow to develop the CART passport! Enjoy reading 😀. www.ebmt.org/education/ca...

29.03.2025 22:26 — 👍 4    🔁 0    💬 0    📌 0
11.03.2025 08:33 — 👍 6    🔁 5    💬 0    📌 0
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The use of MSCs in steroid-refractory acute GvHD in Europe: a survey from the EBMT cellular therapy & immunobiology working party Bone Marrow Transplantation - The use of MSCs in steroid-refractory acute GvHD in Europe: a survey from the EBMT cellular therapy & immunobiology working party

Still hot and happening: academic MSC for GVHD, a study of the CTIWP of The EBMT
rdcu.be/eaCcY

20.02.2025 14:20 — 👍 3    🔁 0    💬 0    📌 0
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The landscape of immune monitoring in CAR-T cell therapy: A comprehensive review and survey study by the Cellular Therapy and Immunobiology Working Party of the EBMT Immune monitoring of cell therapies is a complex and evolving topic, particularly in the rapid expanding field of chimeric antigen receptor T (CAR-T) …

🚀 Fresh off the pre-proof! 🚀
Excited to share our latest work, now available in Blood Reviews
✅ Immune monitoring is widely implemented but still lacks standardization.
✅ There is an urgent need for harmonized protocols to optimize patient outcomes.

www.sciencedirect.com/science/arti...

16.02.2025 12:49 — 👍 4    🔁 1    💬 0    📌 0
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Christian Chabannon presenting on the progress of #GoCARTcoalition a European initiative aiming to increase access to this exciting new therapies to cancer patients and patients with auto immune diseases. #EBMT #EHA #CART25

07.02.2025 07:40 — 👍 3    🔁 0    💬 1    📌 0
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What a great pre meeting before #CART25 in Strassbourg of #T2Evolve and #GoCART coalition on developing consensus on collected CART data as well as registry interactions using OMOPing

06.02.2025 10:24 — 👍 2    🔁 0    💬 0    📌 0
LinkedIn This link will take you to a page that’s not on LinkedIn

We are proud to inform you that the survey about the CAR-T process has resulted in a stunning 227 response. Curious about first data: please join the session at QM Day April 1 at the EBMT congress in Florence, Italy!

#EBMT #JACIE #CART #GOCARTcoalition #HEMATOLOGY

lnkd.in/gQ8dQaps

04.02.2025 13:27 — 👍 2    🔁 0    💬 0    📌 0
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Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis and neuromyelitis optica spectrum disorder — recommendations from ECTRIMS and the EBMT - Nature Reviews Neurolog... Autologous haematopoietic stem cell transplantation (AHSCT) is a treatment option for some forms of multiple sclerosis (MS), but uncertainties remain about its implementation in clinical practice and ...

www.nature.com/articles/s41.... Important consensus paper for centers using autologous stem cell transplant as treatment for Multiple Sclerosis

01.02.2025 07:54 — 👍 2    🔁 0    💬 0    📌 0
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Congrats to the winners!!! Studies with real world data on CART are so important to improve clinical practice. Looking forward to the outcome of these studies thegocartcoalition.com

20.01.2025 11:00 — 👍 4    🔁 0    💬 0    📌 0
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Proud of Anke Janssen who finalized her PhD on the biology of gdT cells and their receptors for cancer in immunotherapies. Yuca also to the co-promotors Dennis Beringer and Moniek de Witte

research.umcutrecht.nl/news/%CE%B3%...

17.12.2024 11:28 — 👍 5    🔁 0    💬 0    📌 0
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Excellent presentation of ⁦‪@CChabannon‬⁩ on tisagenlecleucel for the Management of Patients with R/R DLBCL: an Interim Report of the European PASS Conducted
by EBMT ⁦at #ASH24

10.12.2024 18:12 — 👍 7    🔁 0    💬 0    📌 0
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Thx for picking up our work on MSC for GVHD at #ASH24 …. Still an interesting option

10.12.2024 17:49 — 👍 5    🔁 0    💬 0    📌 0
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#ASH24 Fantastic E. Donnall Thomas Lecture given by Sean Morrison on Hematopoietc Stem Cell Maintenance!

09.12.2024 19:07 — 👍 5    🔁 1    💬 0    📌 0
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Dr. Ing Soo Tiong from @petermaccc.bsky.social presenting his excellent work at #ASH24 on how the remission clonal haematopoietic landscape is shaped by venetoclax in pts with AML. TP53 and BAX microclones! With a bit more sensitive sequencing tech we will find the nanoclones… #hemepath #hemesky

07.12.2024 19:17 — 👍 9    🔁 3    💬 0    📌 0
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Starting #ASH24 on Bluesky 😎

07.12.2024 16:30 — 👍 8    🔁 1    💬 0    📌 0

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