Thomas A. Brinkley

Congratulations to all the Democratic candidates who won tonight. It’s a reminder that when we come together around strong, forward-looking leaders who care about the issues that matter, we can win. We’ve still got plenty of work to do, but the future looks a little bit brighter.

The CRG PhD call is open! 🌟
A truly special place, world-class facilities, an inspiring community, and a training team that really cares about helping each student reach their full potential.
My lab will be recruiting (moving next year), as will many amazing new colleagues!
#CRGPhD2026 #CRGBarcelona

The centriole is crucial for cilia formation, but its molecular architecture is not known. Research from the @Wieczorek Group at ETH Zurich reports structures of the centriole’s A-C linker, revealing how it crosslinks neighboring microtubule triplets. More: biol.ethz.ch/en/news-and-...

Did Amazon trick people into paying for Prime? Federal case goes to trial The U.S. government says Amazon manipulated people into signing up for Prime memberships that were purposefully hard to cancel. The company says its designs and disclosures follow industry standards.

The U.S. government says Amazon manipulated people into signing up for Prime memberships that were purposefully hard to cancel. The company says its designs and disclosures follow industry standards.

plastic tip holders from p10 pipette tip boxes

I have hundreds of these in my gel room. Any good ideas on how to repurpose them? 🧪🔬

These are the most challenging times for early-career scientists and engineers.

My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.

We found 437 of them.

Download it freely here: research.jhu.edu/rdt/funding-...

write good papers and die happy

✨#FluorescenceFriday brings you a glowing Berghia stephanieae juvenile! This stunning sea slug is lit up with Anti-α-Tubulin 🟢, revealing the dense network of cilia that help it glide across surfaces. 🐌💫 Image taken by @Luiza-O-Saad.bsky.social
#Microscopy #DevBio

Mark your calendars! The next ASCB | EMBO Meeting #CellBio2025 is taking place in Philadelphia, US, 6–10 December 2025: www.ascb.org/cellbio2025/ 🧪

@ascbiology.bsky.social‬
#CellBiology #research

The membrane topology problem inherent in ciliogenesis is solved by ciliary recruitment of a phospholipid flippase www.biorxiv.org/content/10.1...

Postdoc position in my lab: investigating how the microtubule motor protein dynein-2 works in cilia.

Here's dynein-2 at work translocating microtubules - how is this activity regulated? How does dynein-2 malfunction in disease?

Find out more and apply:
my.corehr.com/pls/uoxrecru...

MBL Light Microscopy Bootcamp | Marine Biological Laboratory Director:  Ed Munro, University of Chicago

This fall, we are offering a Light Microscopy Bootcamp for graduate students, postdocs, and advanced researchers! 🔬

Students will learn fluorescent microscopy, transmitted light microscopy, image processing, and more using our state-of-the-art systems. Learn more at the link!
bit.ly/4iGt8Yi

Thankful to receive a Best Poster Award at a research conference last week! 🏆🔬 #cilia #cellbio #devbio #bioinformatics

Saying ‘pandemic is over,’ NIH institute starts cutting COVID-19 research Grant terminations halt research on improving vaccinations and preventing future pandemics

Exclusive: Science has learned that grant termination letters went out last night to principal investigators of 29 awards made by NIAID, including nine grants that were part of a program hoping to deliver antiviral drugs to prevent future pandemics. scim.ag/4iVm7mY

Credit: Margot Riggi (@margotriggi.bsky.social), Max-Planck Institute of Biochemistry (@mpibiochem.bsky.social)

Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6

Save the date! Cell Bio 2025, the joint ASCB | EMBO meeting, will take place in Philadelphia, US, 6 – 10 December 2025:
www.ascb.org/cellbio2025/
#CellBio2025 @ascbiology.bsky.social 🧪

openRxiv has arrived!

We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences.
openrxiv.org/introducing-...

#openRxiv #OpenScience #Preprints #bioRxiv #medRxiv

Sharing some oocyte spindle love-an image taken by PhD student Phia Maddocks. This beautiful work is supported by our NIH funding. Without this funding, we cannot understand the complexities of fertility genetics. With declining fertility rates, this work is essential to human health.

Doing good science is 90% finding a science buddy to constantly talk to about the project.

I stood up today - and so did Beaker!
#standupforscience2025 #standupforscience
@standupforscience.bsky.social

Drosophila Alms1 proteins are general regulators of #centriolar cartwheel assembly, exhibiting distinct centriolar localization patterns and enabling Plk4-Ana2 interaction
#RefereedPreprint c/o @reviewcommons.org by Véronique Morel, Bénédicte Durand and colleagues
www.embopress.org/doi/full/10....

Do you mind if I use it for my poster on Friday? It’s a great idea.

Screencap from Mean Girls. In this scene, Cady and Aaron are in math class. Aaron is turned backwards in his seat and asking Cady what day it is. She, of course, responds "It's October 3rd."

On March 3rd, he asked me what day it was.

It's March 3rd... FOUR DAYS BEFORE WE STAND UP FOR SCIENCE 🎉🎉🎉🎉

Federal technology staffers resign rather than help Musk and DOGE Twenty-one civil service employees have resigned from billionaire Trump adviser Elon Musk’s Department of Government Efficiency, saying they're refusing to use their technical expertise to “dismantle ...

More than 20 civil service employees are resigning from Elon Musk’s DOGE, saying they refuse to “dismantle critical public services.”

Top: Graphical representation of current working model. Bottom: Representative immunofluorescence images of SKBR3 parental, DKO or CASP3 + 7-WT re-expression in DKO cells treated with 0.25 µM DALGreen in fed (top row) or starved (bottom row) conditions. BafA1 in both fed and starved conditions serves as controls.

Caspases have well known roles in #apoptosis, but roles in other cellular processes are emerging... This study shows that #caspase -3 & -7 promote cytoprotective #autophagy in response to non-lethal stress by modulating PARP1 activity in #BreastCancer cells 🧪 @plosbiology.org plos.io/41xfLVm

NIH funding freeze stalls applications on $1.5 billion in medical research funds The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

Cyan - TH Red - Iba1 Green - GFAP Blue - DAPI

Happy #fluorescencefriday to the microscopy folks of Bluesky! 🧪

Please enjoy this image hot off the slide scanner piloting our new decon module in a murine #Parkinsons model

Biggest-ever AI biology model writes DNA on demand An artificial-intelligence network trained on a vast trove of sequence data is a step towards designing completely new genomes.

🧪 Evo-2, the largest AI model for biology, is here. Trained on 128K genomes, it can generate entire chromosomes and decode noncoding DNA linked to disease. Scientists see it as an "app store" for biology. 🧬💻

‘I really wanted something to happen.’ The students behind the Stand Up for Science protests New group hopes to turn out researchers for 7 March demonstrations against Trump administration policies

Scientists are now organizing events, called Stand Up for Science, on 7 March in Washington, D.C., and state capitals.

So far, they have attracted more than 100 volunteers from some 30 states who are hoping to rally support for research as a public good. scim.ag/4328LAD