The Friedman Brain Institute

THANK YOU to the AWESOME #FBIResearchScholars Award donors — Joseph DiSabato & Nancy Sakamoto, Michael & Beth Fascitelli, Richard & Susan Friedman, Stuart Katz & Dr. Jane Martin, Joshua & Beth Nash, Ram Sundaram & Preethi Krishna, the Glickenhaus Family & the Lipschultz Family!

A HUGE CONGRATULATIONS to the 2026 #FBIScholars Awardees! The FBI Scholars Award gives both young & established investigators the freedom & flexibility to explore the most audacious ideas in brain science. THANK YOU to our amazing donors w/o whom this award would not be possible!

Exciting to see this paper out!

Data shows episodic memory is dependent on a small number of precisely timed, transient, internally-generated states.

Understanding these precise spatial and temporal dynamics is key to developing accurate and effective memory enhancement strategies 🧠

Neural Implant podcast - the people behind Brain-Machine Interface revolutions: Ignacio Sáez - Neurotechnology for Cognition: Recording and Modulating the Human Brain In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with Dr. , , whose lab uses intracranial brain recordings to study the biology of human cognition. Ignacio shares how cu...

Thanks to Ladan Jiracek for having me on the Neural Implant Podcast!

We discussed how clinical neuroscience is combining high-resolution brain recordings with sophisticated behavioral studies to provide a truly comprehensive characterization of the human brain.

🎧 Listen here: tinyurl.com/yx47525v

💡The neural mechanisms behind "aha!" moments are revealed in @natcomms.nature.com.

Bridging computational neuroscience and AI, this approach offers insights into learning in biological and artificial systems.

Congrats to @biyuhe.bsky.social and team! Proud to be part of this work.

Learn more 👇

Ever wondered how the Dalmatian Dog effect works?

The human brain can quickly learn from a single experience and generalize it to related experiences — an impressive feat so far not matched by AI.

Our new paper in @natcomms.nature.com reveals how this works.
www.nature.com/articles/s41...

Mindfulness-Oriented Recovery Enhancement rebalances prefrontal responses to drug and natural reward cues in opioid use disorder Despite decades of clinical implementation of medications for opioid use disorder (OUD), overdose mortality rates remain high, underscoring a critical gap in treatments that target brain mechanisms dr...

Check out our new preprint documenting how Mindfulness-Oriented Recovery Enhancement rebalances neural responses to drug and natural reward cues in opioid use disorder! W/ Yuefeng Huang, @narcatms.bsky.social, @drericgarland.bsky.social et al
@sinaibrain.bsky.social
www.medrxiv.org/content/10.6...

🌺 SPRING IS COMING! 🎨 + 🧠 = The #ArtoftheBrain Call for Images is OPEN! @mountsinainyc.bsky.social employees w/ a valid #MountSinai email address are invited to submit high quality, visually compelling works of brain-related #sciART. Photographs Video Figures etc. 👉 form.jotform.com/mssmneur0/20...

Major depressive disorder shares systemic immune signatures and potential therapeutic targets with inflammatory skin diseases - Molecular Psychiatry Molecular Psychiatry - Major depressive disorder shares systemic immune signatures and potential therapeutic targets with inflammatory skin diseases

NEW STUDY! "#MajorDepressiveDisorder shares systemic immune signatures and potential therapeutic targets w/ inflammatory skin diseases" - Emma Guttman, James Murrough, et al. @mountsinainyc.bsky.social CHECK IT OUT in Molecular Psychiatry @natureportfolio.nature.com 👉 www.nature.com/articles/s41...

According to NEW STUDY, #MajorDepressiveDisorder shares immune abnormalities and potential therapeutic targets with inflammatory skin diseases. Findings provide rationale for targeted strategy that may lead to new personalized treatments. PRESS RELEASE👉 www.mountsinai.org/about/newsro...

TODAY 👉 On 2/12, 2pm, JOIN @biausa.bsky.social, @nationalacademies.org & @sinaitbi.bsky.social's Dr. @dams-oconnor.bsky.social for a clinically-focused webinar on latest science & evidence-based strategies to improve care of people living w/ chronic #TBI symptoms. Register 👉 zoom.us/webinar/regi...

🌺 SPRING IS COMING! 🎨 + 🧠 = The #ArtoftheBrain Call for Images is OPEN! @mountsinainyc.bsky.social employees w/ a valid #MountSinai email address are invited to submit high quality, visually compelling works of brain-related #sciART. Photographs Video Figures etc. 👉 form.jotform.com/mssmneur0/20...

THURSDAY! On 2/12, 2pm, join @biausa.bsky.social, @nationalacademies.org & @sinaitbi.bsky.social's Dr. @dams-oconnor.bsky.social for clinically-focused webinar on latest science & evidence-based strategies to improve care of people living w/ chronic #TBI symptoms. Register 👉 zoom.us/webinar/regi...

🎉HUGE CONGRATULATIONS @paulkennyphd.bsky.social! We are delighted to announce the appointment of world-renowned neuroscientist Dr. Paul Kenny as Director of the #FriedmanBrainInstitute, one of the nation's largest neuroscience research hubs dedicated to understanding brain function. Wonderful news!👏

🧠On 2/24, the #BrainBodyResearchInstitute Seminar Series & Dr. Hongzhen Hu host @nyupress.bsky.social's Dr. Kara Margolis. @margolislabnyu.bsky.social's research is focused on discovering ways to alter gut signaling to treat disorders of brain & GI tract. Register👉 mountsinai.zoom.us/webinar/regi...

OUT NOW! In this review, Viksar Dubey & Li Shen highlight strategies that have been employed to address current limitations of #DeepLearning models & explore methods aimed at improving the prediction of personalized gene expression. ➡️ academic.oup.com/bib/article/...

@mountsinainyc.bsky.social

In @businessinsider.com, @mountsinainyc.bsky.social's Drs. Alexander Charney & Noam Beckmann, discuss their groundbreaking study "Establishing the relationship between brain cellular senescence and brain structure"👉 markets.businessinsider.com/news/stocks/... FULL STUDY👉 www.cell.com/cell/fulltex...

For Continuing Education Units (CEUs), register for "Redefining Recovery: Addressing #TBI as a Chronic Condition" through @biausa.bsky.social 👉 learn.biausa.org

On 2/12 at 2pm, join @biausa.bsky.social, @nationalacademies.org & Dr. @dams-oconnor.bsky.social, Director @sinaitbi.bsky.social, for clinically-focused webinar on latest science & evidence-based strategies to improve care of people living w/ chronic #TBI symptoms. Register👉 zoom.us/webinar/regi...

Thru an unbiased, forward genetic screen in Drosophila,
@volluminstitute.bsky.social's Dongeun Heo found unexpected, non-neuronal role for dSarm/SARM1 pathway in #Astrocyte morphogenesis. INTERESTED? JOIN Swagata Dey, Batuhan Ayci & @chloelopezlee.bsky.social when they host Dr Heo at #MSNseminars

In a NEW STUDY, @mountsinainyc.bsky.social researchers Dr. Jonathan DePierro, et al. identify barriers to #MentalHealth service use among health system employees. Learn More in the Journal of Occupational and Environmental Medicine 👉 journals.lww.com/joem/abstrac...

A bittersweet farewell to the Cai Lab and Mount Sinai ❤️. 7 incredible years with some of the kindest, fun, inspiring people I've ever met. So many lab antics, life lessons, amazing meals, and scientific discoveries. I will miss them dearly. @denisejcai.bsky.social @sinaibrain.bsky.social

TONIGHT, Jan 26! No❄️Day! Weather you have to⛷️🏂or🛷, make sure to JOIN @storycollider.bsky.social at Caveat NYC when Diana Li & @paulacroxson.bsky.social host @denisejcai.bsky.social & 4 other #StoryTellers for an unforgettable evening of deeply personal stories. TIX👉 storycollider.org/tickets/2026...

Already-available therapy could protect football players from CTE: ‘Incredibly groundbreaking’ “When we first started this project, I was extremely skeptical,” said Dr. Elisabeth Wilde. “But we’ve seen consistent results across multiple of our studies, so it’s starting to be quite compelling…

NEW STUDY from @utah.edu suggests red light therapy may one day offer a valuable tool in fight against #CTE. In @nypost.com, @sinaitbi.bsky.social's Dr. Kristen Dams O'Connor offers her perspective👉 nypost.com/2026/01/22/h... FULL STUDY in Journal of Neurotrauma👉 journals.sagepub.com/doi/10.1177/...

Establishing the relationship between brain cellular senescence and brain structure Cellular senescence and brain structural changes represent defining features of aging, yet their relationship remains poorly understood. This study demonstrates a molecular link between these processe...

NEW STUDY OUT NOW! ! Establishing the relationship between brain cellular senescence and brain structure - Anina Lund, Brian Kopell, @ericjnestler.bsky.social, @alexcharney.bsky.social, Noam Beckmann, et al. READ FULL TEXT @cellpress.bsky.social www.cell.com/cell/fulltex...

NEW! Researchers Anina Lund, Brian Kopell, @ericjnestler.bsky.social, @alexcharney.bsky.social, Noam Beckmann, et al. @mountsinainyc.bsky.social have characterized how cellular senescence is assoc w/ human brain structure in both dvlpmnt & late life PRESS RELEASE👉 www.mountsinai.org/about/newsro...

In this INTERESTING and INFORMATIVE interview w/ Psychiatric Times, @ericjnestler.bsky.social reflects on his decades of work in #Depression and #Addiction sciences, along with his new role as dean of the Icahn School of Medicine at Mount Sinai. Watch here👉 www.psychiatrictimes.com/view/innovat...

What is #CTE? What is the prevalence of CTE? Can CTE be diagnosed during life? These are but a few of the important questions pertaining to #ChronicTraumaticEncephalopathy. Join this important discussion & Learn More w/ @sinaitbi.bsky.social's Dr. Kristen Dams-O'Connor 👉 bjsm.bmj.com/content/earl...

INTERESTED in the @mountsinainyc.bsky.social Students for Rare club activities and future events? For more information please email 👉 brooke.friedman@icahn.mssm.edu or david.donofrio@icahn.mssm.edu @sinaigenetics.bsky.social

The #MountSinai Students for Rare club, a chapter of @nordrare.bsky.social, recently hosted its inaugural Rare Disease Professional Panel. Leaders from research, clinical care, advocacy, patient experience & the arts highlighted the rare disease community as a powerful force for good.