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Ganuza Lab

@ganuzalab.bsky.social

Developmental Biology Lab focused on normal and malignant hematopoiesis. We employ synthetic biology to tackle fundamental biological and medical questions. https://www.ganuzalab.org Barts Cancer Institute, QMUL @qmbci.bsky.social

64 Followers  |  58 Following  |  13 Posts  |  Joined: 10.12.2024
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Posts by Ganuza Lab (@ganuzalab.bsky.social)

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Explore the February #ExpHem issue, with articles from the labs of Jean-Pierre LΓ©vesque, @ganuzalab.bsky.social, Katrin Ottersbach, Duonan Yu and more! Read the latest research in experimental hematology now on www.exphem.org.

18.02.2026 21:01 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Thanks Shannon

17.01.2026 15:54 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar Allotransplantation provides a lifesaving treatment to hundreds of thousands of patients worldwide every year, including among others heart, kidney, liver and bone marrow (BM) transplants [1,2]. Yet, ...

Have you ever wondered about Pig HSCs? Today is your lucky day! Check out this excellent work from @ganuzalab.bsky.social. Well done!
Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar. www.exphem.org/article/S030...
@isehsociety.bsky.social

17.01.2026 13:53 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Merry Xmas to you and your family from our lab. πŸŽ…πŸŽ„πŸŽ‰πŸŽ„πŸŽ…β˜ƒοΈβ˜ƒοΈπŸŽ‰

24.12.2025 12:28 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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HSC-independent and -dependent hematopoiesis: new insights and lineage tracing methods. Hematopoietic cells are mesodermal in origin and emerge through a highly regulated process known as endothelial-to-hematopoietic transition (EHT), which yields various hematopoietic progenitors 1,2 In...

Check out our collaborative Review Article with Dr Momoko Yoshimoto on:
HSC-independent and -dependent hematopoiesis: new insights and lineage tracing methods. - Experimental Hematology www.exphem.org/article/S030...

@isehsociety.bsky.social @qmbci.bsky.social

21.12.2025 13:47 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Many thanks Raquel!

14.12.2025 16:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar Allotransplantation provides a lifesaving treatment to hundreds of thousands of patients worldwide every year, including among others heart, kidney, liver and bone marrow transplants1,2. Yet, thousand...

Check our new article:
Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar

We must understand pig hematopoiesis to enable bone marrow xenotransplantation.

@qmbci.bsky.social
Emma Bailey
@foteinikal.bsky.social

www.exphem.org/article/S030...

14.12.2025 08:58 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
ASH Commits More than $12 Million to Address Research Threats - Hematology.org ASH Commits More than $12 Million to Address Research Threats

ASH is committing more than $12 million to address research funding challenges and support the next generation of hematologists.

Learn more: ow.ly/sK3050W735W

10.06.2025 15:20 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Thanks @isehsociety.bsky.social for featuring our lab. #SimplyBlood. Thanks @billgrey.bsky.social for the interview.

05.03.2025 07:17 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Yay @ganuzalab.bsky.social! So proud of my former trainee and his wonderful lab.

05.03.2025 03:09 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Thanks @smckinneyfreeman.bsky.social

05.03.2025 06:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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This week on #SimplyBlood 🩸 we're highlighting the @ganuzalab.bsky.social lab out of the Centre for Haemato-Oncology Barts Cancer Institute, Queen Mary University of London, UK. Read more on www.simplyblood.org

04.03.2025 22:15 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 0    πŸ“Œ 2

Thanks 😊

02.03.2025 12:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Pubmed down! Expected under the current craziness.

02.03.2025 11:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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πŸ”₯ New Fraticelli lab publicationπŸ”₯

β€œPre-existing stem cell heterogeneity dictates clonal responses to the acquisition of leukemia driver mutations”

Now at Cell Stem Cell, with two new figures, in vivo, and sequential mutagenesis data.

Performed with the support of Cris Cancer and @erc.europa.eu

25.02.2025 16:24 β€” πŸ‘ 109    πŸ” 26    πŸ’¬ 9    πŸ“Œ 1

#ESHMICRO2025

17.02.2025 21:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Raúl SÑnchez-Lanzas and Foteini Kalampalika @foteinikal.bsky.social presenting their work on clonal hematopoiesis and aplastic anaemia at the Haematological Tumour Microenvironment Meeting ESH in London!!! Well done guys 😊!!

17.02.2025 21:09 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Are the Trump team’s actions affecting your research? How to contact Nature Use this form to share information with Nature’s news team, or to make suggestions for future coverage.

Use this form to tell us how the new US administration is affecting your research, or suggest future coverage

https://go.nature.com/42SyoUu

13.02.2025 13:12 β€” πŸ‘ 148    πŸ” 135    πŸ’¬ 0    πŸ“Œ 7

More Federicos and less Trumps

12.02.2025 10:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Federico Mayor Zaragoza obituary: former UNESCO chief who championed neonatal screening The biochemist introduced the first heel-prick tests for newborn babies in Spain, protecting infants from life-changing metabolic conditions.

Obituary: Federico Mayor Zaragoza (1934-2024) former UNESCO chief who championed neonatal screening

https://go.nature.com/3WXw9LQ

11.02.2025 18:03 β€” πŸ‘ 50    πŸ” 15    πŸ’¬ 1    πŸ“Œ 1
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Senolytics Restore Hematopoietic Stem Cells Function in Sickle Cell Disease Sickle Cell Disease (SCD) is a blood disorder affecting millions worldwide. Emerging evidence reveals that SCD pathophysiology increases risk of myeloid malignancies and hematopoietic stem cell (HSC) ...

Excited to share our work - online today as a preprint. Here, we characterize precocious aging in HSCs of mice and people with sickle cell disease. Excitingly, we demonstrate the potential of senolytics to restore HSC function to the bone marrow of mice with SCD.

www.biorxiv.org/content/10.1...

10.02.2025 02:51 β€” πŸ‘ 12    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones - Leukemia Leukemia - A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones

@ganuzalab.bsky.social
Exciting new work from my former trainee, Mikel Ganuza, now running his own excellent team. Congrats!
#HSCs #clonalhematopoiesis
#science

www.nature.com/articles/s41...

29.01.2025 04:30 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Thanks so much @smckinneyfreeman.bsky.social

29.01.2025 07:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0