📣 Join @katiecorker.bsky.social (ASAPbio), @thewilkybarkid.bsky.social, and @neurosarda.bsky.social (@prereview.bsky.social) on March 5th for the Community Call!

Speakers will discuss the ins and outs of doing open peer review as part of a team🤝

Register 👇️
buff.ly/5I0wC4l

Peer Review Resource Center – ASAPbio Find comprehensive resources and best practices for transparent, constructive peer review of life science research.

Open & transparent preprint review means:
✅Faster feedback
✅Crediting reviewers for their contributions
✅Public, constructive discussion

Are you new to preprint peer review and unsure where to begin? Check out the ASAPbio Peer Review Resource Center to learn more!

Menopausal Hormone Therapy Does Not Increase Mortality An analysis of over 800,000 women found no association between the use of menopausal hormone therapy and increased mortality.

👵An analysis of over 800,000 women found no association between menopausal hormone therapy and increased mortality.

For some groups of women, this therapy lowers mortality risk.

lifespan.io/news/menopau...
By: @drangowskaway.bsky.social

Lifetime Cognitive Enrichment Associated With Less Dementia Cognitive enrichment throughout life is associated with reduced dementia risk, and it has the potential to delay dementia and mild cognitive impairment.

A recent study suggests that cognitive enrichment 📚🌍📰throughout life:
🧠is associated with reduced dementia risk, and
🧠has the potential to delay the onset of dementia and mild cognitive impairment by five to seven years.

lifespan.io/news/lifetim...
By: @drangowskaway.bsky.social

Young Microbes Rejuvenate Intestinal Function in Mice Transferring microbiota from young to aged mice restored molecular signaling for intestinal function and improved the regeneration of intestinal stem cells.

In a recent study, researchers transferred microbiota from young to aged mice. 🦠🐁
The transfer helped to restore molecular signaling necessary for proper intestinal function and improved the regenerative capacity of intestinal stem cells.

lifespan.io/news/young-m...
By: @drangowskaway.bsky.social

Need an idea for your next Journal Club? Discuss a #preprint!
💪 Help the authors strengthen their work
🗣️ Discuss science as it happens
🥼 Help raise your and your group’s profile
📰 No restrictions on papers to include
🧪 Focus on the science

Association Between Vitamins and Slower Biological Aging An analysis of data of 15,000 participants and 11 vitamins found that higher vitamin intake is associated with slower biological aging.

A recent study suggested that higher vitamin intake, particularly of Vitamins C and B2, is associated with slower biological aging.
However, not all vitamins showed the same beneficial effects.

lifespan.io/news/associa...
By: @drangowskaway.bsky.social

Shingles Vaccination Is Associated With Slower Aging Shingles vaccination is associated with lower inflammation scores, slower epigenetic and transcriptomic aging, and a lower composite aging score.

A new study found that shingles vaccination 💉 is associated with:
🔥lower inflammation scores,
🧬slower epigenetic and transcriptomic aging, and
🧓a lower composite biological aging score.

lifespan.io/news/shingle...
By: @drangowskaway.bsky.social

The Impact of Childbearing Trajectories on Aging The authors of a recent study investigated the relationship between reproduction (number and timing of children), aging, and survival. An analysis of seven distinct reproductive trajectories suggested...

👶Does having babies impact how fast you age?
A new study that investigated various childbearing trajectories suggests accelerated aging and increased mortality risk in women with multiple live births, as well as childless women.

lifespan.io/news/the-imp...
By: @drangowskaway.bsky.social

The Geroprotective Potential of Hormone Replacement Therapy A recent review of literature investigated the risks and benefits of hormone replacement therapy. The authors point out that this approach could […]

A recent review of literature investigated the risks and benefits of hormone replacement therapy. The authors point out that this approach could be used as a geroprotector to extend the healthspan of women.
lifespan.io/news/the-ger...
By: @drangowskaway.bsky.social
#WomensHealth #aging #menopause

How Multivitamins and Minerals Impact Health and Longevity A recent review evaluated studies that included over 5.5 million participants to assess the impact of multivitamin and mineral supplements on different aspects of health [1]. A big market Multivitamin...

A recent review evaluated studies that included over 5.5 million participants to assess the impact of multivitamin and mineral supplements on different aspects of health.

www.lifespan.io/news/how-mul...
By: @drangowskaway.bsky.social

Recombinant Human Protein Stops Neuronal Loss in Alzheimer’s A recent study investigated biomarkers that can help monitor trajectories of Alzheimer’s disease-related molecular processes, such as neuronal cell death, and how patients respond to treatments. The a...

🧠An investigation into Alzheimer’s disease-related biomarkers provided insights into the molecular processes that contribute to improved cognition following treatment with a human recombinant protein.

lifespan.io/news/recombi...
By: @drangowskaway.bsky.social

Analyzing the Quality of Preclinical Anti-Aging Research Researchers have investigated the reporting quality of preclinical studies’ outcomes in anti-aging research. They analyzed how study quality changed over time, shortcomings in research, and the improv...

A recent study investigated the reporting quality of preclinical studies’ outcomes in anti-aging research.
The results suggest improvements are necessary if we want the research to yield as many valuable insights as possible.

www.lifespan.io/news/analyzi...
By: @drangowskaway.bsky.social

Human Umbilical Cord Blood Metabolites Lengthen Worms’ Lives Comparison of human umbilical cord blood with adult plasma revealed hundreds of metabolites whose abundances were age-dependent. Two different formulas, each […]

Comparison of human umbilical cord blood with adult plasma identified metabolites with anti-senescence properties.
Those molecules are more abundant in cord blood and decline with age.

www.lifespan.io/news/human-u...
By: @drangowskaway.bsky.social

Second-Hand Smoke Alters Protein Expression A recent study investigated plasma proteins in people exposed to secondhand smoke and found that exposure affected multiple molecular processes, including immune, inflammatory, and tissue repair pathw...

🚬Exposure to secondhand smoke affects multiple molecular processes, including immune, inflammatory, and tissue repair pathways, a study suggests.

www.lifespan.io/news/second-...
By: @drangowskaway.bsky.social

In my opinion, if the difference is that big, then yes, such a person would be considered bilingual.
However, I am not a specialist in linguistics.

I'm happy the article was encouraging to you. A multilingual person is someone who regularly uses more than one language. And yes, someone who speaks Spanish and Italian (or Dutch and German) is bilingual. I am bilingual because I speak Polish and English :)

Good luck with your studies!

Multilingualism Is Associated With Delayed Aging A recent study of over 80,000 Europeans concluded that speaking more than one language is associated with delayed aging. Further analysis suggested that the protective effect of speaking one foreign l...

💬Hello! Hola! Cześć! こんにちは!
Speaking more than one language is associated with delayed aging, according to a recent study!

www.lifespan.io/news/multili...
By: @drangowskaway.bsky.social
#Multilingualism #bilingual #polyglot #LanguageLearning

It was wonderful to work with you! Best of luck in your new adventure!

Organ Fat Is Associated With Carotid Atherosclerosis A recent study discovered an association between visceral and, to a lesser extent, hepatic fat with cardiovascular risk factors and carotid atherosclerosis. This association persists even after adjust...

A recent study discovered an association between visceral and hepatic fat with cardiovascular risk factors and carotid atherosclerosis.

www.lifespan.io/news/organ-f...
By: @drangowskaway.bsky.social

Rapamycin May Delay Age-Related Fertility Decline In a recent study, researchers identified that an increase in the expression of ribosome-related genes and a loss of protein homeostasis […]

Researchers identified changes in the expression of genes in eggs and their surrounding cells, which contribute to the age-related decline in female fertility.♀️
💊Rapamycin restored balance and increased fertility rates in human trials.👶
www.lifespan.io/news/rapamyc...
By: @drangowskaway.bsky.social

Addressing Age-Related Vision Decline With Lipid Supplements Researchers have partially reversed age-related vision decline in mice by injecting lipids directly into the retina [1]. The lipids in the […]

Researchers demonstrated a proof-of-concept for turning lipid injection, directly into the retina, into a possible therapy for age-related vision decline.👀
In a new study such treatment partially reversed vision decline in mice.
www.lifespan.io/news/address...
By: @drangowskaway.bsky.social

Reasserting Community Control Over Who Owns Our Knowledge — International Open Access Week With today’s start to International Open Access Week, important conversations will take place across the world exploring how communities can reassert control over the knowledge they produce. This year...

A reflection on this year's #OAweek theme & a snapshot of upcoming presentations. For a full list of events go to the #OpenAccess Week website: www.openaccessweek.org/events
www.openaccessweek.org/blog/2025/re...

Myth 3: Preprints are not discoverable or citable Myth: “Preprints are not discoverable or citable.” Truth: Preprints are an established part of today’s research ecosystem—they have DOIs, appear in major databases, and are recognized by both…

Think preprints are invisible? 👀
They’re not! Discover how preprints are findable, citable, and transforming scholarly communication in our latest ASAPbio Myth Busting whiteboard video.🎬
🎥 Watch here → buff.ly/qzAeHH0
#Preprint #OpenScience #ScholComm #ScientificPublishing

Interventions Testing Program Finds Three New Compounds A new report from the Interventions Testing Program adds three new compounds to the list of lifespan-extending compounds confirmed during their experiments: epicatechin, halofuginone, and mitoglitazon...

A new report from the Interventions Testing Program adds three new compounds to the list of lifespan-extending compounds confirmed during their experiments.
However, these compounds extend lifespan only in male ♂️ mice.🐁
www.lifespan.io/news/interve...
By: @drangowskaway.bsky.social

Impact of Off-Label Low-Dose Rapamycin on Healthy Adults A team of scientists has reviewed the clinical data regarding low-dose rapamycin therapy in healthy adults. They concluded that, while there is plenty of preclinical data regarding the impact of rapam...

Plenty of preclinical studies investigated rapamycin and showed its benefits in model organisms. However, can rapamycin extend healthspan and lifespan in healthy humans?
A review of clinical studies sheds light on that question.
www.lifespan.io/news/impact-...
By: @drangowskaway.bsky.social

Partial Reprogramming Rejuvenates Aged Cells and Tissues In a recent study, researchers investigated aging- and disease-associated changes in gene expression related to epithelial-mesenchymal transition. Inducing the Yamanaka factors in mice allowed them to...

A recent study showed that Yamanaka factors can partially reprogram gene expression patterns related to cellular identity, leading to rejuvenation in cells and tissues, independent of inducing pluripotency.

www.lifespan.io/news/partial...
By: @drangowskaway.bsky.social

Personalized Medicine Approach to Senolytics Clinical Trials Recent commentary in Nature Aging summarized the results of clinical trials for senolytics and discussed recommendations for future clinical trials that use personalized medicine approaches [1]. From ...

Personalized medicine strategies are entering the longevity field.

A recent paper discusses the results of senolytics clinical trials and how senolytics might work better in people with higher senescent cell burdens.

www.lifespan.io/news/persona...
By: @drangowskaway.bsky.social

Cell Cycle Stage Impacts the Efficacy of Senotherapeutics A recent study reported that the effectiveness of the senotherapeutic drug ABT-263 depends on the cell’s DNA content, which is based […]

A recent study reported that the effectiveness of the senotherapeutic drug ABT-263 💊 depends on the cellular division stage at which the cell became senescent.

www.lifespan.io/news/cell-cy...
By: @drangowskaway.bsky.social

Regular Glucosamine Use Linked to Fewer Chronic Diseases An analysis of UK Biobank data showed an association between regular glucosamine use and significantly lower risks of seven non-communicable chronic diseases [1]. […]

An analysis of UK Biobank data showed an association between regular glucosamine 💊 use and significantly lower risks of seven non-communicable chronic diseases.📉

www.lifespan.io/news/regular...
By: @drangowskaway.bsky.social