A two year post-doctoral position at the BacterialGenome Plasticity Unit starting October 1st - Research
A 2-year postdoc position in my lab, under the supervision of P-Alex Kaminski, on Z-DNA phages and the benefit given by ZTGC DNA and the replication machinery, with attempt to create a Z based minireplicon
research.pasteur.fr/en/job/a-two...
28.07.2025 10:30 β π 42 π 48 π¬ 0 π 0
@cascaleslab.bsky.social
25.07.2025 04:26 β π 0 π 0 π¬ 0 π 0
New study reveals a CD38-like ADP-ribosyl cyclase toxin delivered by T6SS that depletes NAD+ in both bacterial and eukaryotic cells.
A striking case of structural mimicry, cross-immunity, and widespread deployment in microbial warfare.
βοΈβͺ @jmartinkus.bsky.social & coll.
π shorturl.at/b5LSB
#MicroSky
25.07.2025 04:26 β π 5 π 1 π¬ 2 π 0
Portail Emploi CNRS - Offre d'emploi - IngΓ©nieur d'Etude en Microbiologie (H/F)
We have an open engineer position to work on type IX secretion (T9SS), under the supervision of @doan_thierry (collab with HP Fierobe & A. Tolonen). 1-year contract, renewable up to 3.5 years. Please apply here or forward to anyone potentially interested:
emploi.cnrs.fr/Offres/CDD/U...
08.07.2025 14:54 β π 23 π 32 π¬ 0 π 0
A new study delivers the most comprehensive phylogenomic analysis of Spirochaetes to date, revealing their deep evolutionary roots and shedding light on the loss of spiral morphology and host adaptation.
βοΈ @microbiomol.bsky.social and coll. @pasteur.fr
π shorturl.at/UxAWu
#MicroSky
07.07.2025 05:20 β π 8 π 3 π¬ 0 π 0
E. coli and P. aeruginosa need the Hsp90 chaperone to produce key virulence factors colibactin & pyoverdine, study reveals. Hsp90 stabilizes megasynthases behind complex metabolite biosynthesis. New angles on infection control & biotech tools!
π shorturl.at/n1Pu6
βοΈ Fratacci, Chaouche & coll. #IMM
03.07.2025 05:06 β π 4 π 0 π¬ 0 π 0
New insights into Shigella flexneri pathogenesis: the VapBC TA system is activated during intracellular infection, coordinating stress adaptation, T3SS-mediated virulence, and immune evasion, new study reveals.
βοΈ E. Saifi & coll. @inem-necker.bsky.social @pasteur.fr
π shorturl.at/26d33
#MicroSky
01.07.2025 04:21 β π 8 π 2 π¬ 0 π 0
A new path in the fight against AMR!
Using B cells from CF patients, researchers isolated human mAbs targeting the T3SS of P. aeruginosa. Structural & functional data reveal distinct neutralization modes, blocking virulence without antibiotics! #MicroSky
βοΈ βͺJM Desveaux @ coll.
π shorturl.at/2hixd
26.06.2025 04:41 β π 0 π 0 π¬ 0 π 0
A prophage-encoded single-stranded DNA-binding protein (SSBP) from S. aureus attenuates bacterial virulence and enhances macrophage activation via IL-6, new study reveals. SSBP boosts immune clearance and shows therapeutic potential. #MicroSky #Phage
βοΈ Ahmad-Mansour & coll.
π shorturl.at/6yqFx
17.06.2025 04:06 β π 4 π 0 π¬ 0 π 0
Dynamic excision of the F13 hlb-converting prophage in Staph. aureus is critical for full virulence, new study reveals. Loss of F13 restores Ξ²-hemolysin expression and enhances pathogenicity, while locking the prophage impairs infection. #MicroSky
βοΈ O. Poupel & coll @pasteur.fr
π shorturl.at/F1W3t
13.06.2025 10:00 β π 9 π 4 π¬ 1 π 0
Uropathogenic E. coli uses a novel two-gene system, DanRI, to outsmart neutrophils by blocking NETs and ROS. Induced by host nucleosomes, DanRI boosts bacterial survival & persistence. A new twist in immune evasion!
βοΈ @doracerina.bsky.social & coll.
π shorturl.at/cAj05
#MicroSky
12.06.2025 11:38 β π 4 π 1 π¬ 1 π 0
Nearly half of bacteria carry mobile, accessory PDF enzymes that can resist actinonin, new study reveals. Resistance to PDF-targeting antibiotics is already encoded and poised to spread.
#AMR #MicroSky
βοΈ @morgan-lamberioux.bsky.social and coll.
@pasteur.fr
π shorturl.at/WTBVx
10.06.2025 03:41 β π 12 π 5 π¬ 0 π 0
New study reshapes our view of sleeping sickness: #Trypanosoma brucei persists in fatty skin tissues and uses host-derived glycerol to get transmission-ready, even when blood levels are low.
#SleepingSickness #ScienceNews #Parasites
βοΈF. Bringaud & coll.
πhttps://shorturl.at/LGGxk
28.05.2025 04:35 β π 0 π 0 π¬ 0 π 0
Antibiotics disrupt gut microbes, but what about their viruses?
A new study finds that gut phages crash, bloom, and bounce back after antibiotics, helping restore microbial balance via kill-the-winner dynamics.
βοΈ @eugenpfeifer.bsky.social & coll.
π shorturl.at/AtafX
#MicroSky #AMR
27.05.2025 04:25 β π 31 π 9 π¬ 1 π 0
π¨My new team at @ipbstoulouse.bsky.social in France currently have an open, fully-funded PhD position π§βπ¬π©βπ¬to study membrane proteins & transporters of therapeutic interest using cryo-EM & biophysics.π§π¬π¦
#StructuralBiology #MicroSky
Please share π€
For more details π
21.05.2025 09:30 β π 22 π 15 π¬ 2 π 0
I will be recruiting new postdocs with start dates end 2025 - early 2026. If you'd like to work at the Pasteur Institute in the heart of Paris surrounded by amazing scientists, reach out to discuss possible projects on SynBio / Bacterial Immunity!
18.05.2025 15:19 β π 85 π 79 π¬ 3 π 2
New study reveals that Salmonella can replicate inside macrophages even without its T3SSs, if the nutrient conditions are right! Metabolic heterogeneity of host cells is a game-changer in bacterial replication dynamics. #MicroSky
βοΈ @pescoll.bsky.social and coll. @pasteur.fr
π shorturl.at/a9a06
17.05.2025 06:41 β π 6 π 1 π¬ 1 π 0
Why did Omicron dominate the #COVID19 waves?
New study reveals: Faster replication in human nasal tissue, Disruption of motile cilia & Stealthy evasion of innate immune defenses
Omicron wasnβt just fast, it was sneaky!
βοΈ @lisachakrabarti.bsky.social and coll. @pasteur.fr
shorturl.at/ByGOh
07.05.2025 05:14 β π 10 π 7 π¬ 0 π 2
New study reveals how segmented filamentous bacteria attach to the gut lining: a unique tip structure on their intracellular offspring is key! Cryo-EM shows a novel S-layer transition at the tip, critical for immune-boosting host interaction. #Microsky
π shorturl.at/gXueL
βοΈ P. Schnupf and coll.
11.04.2025 13:37 β π 6 π 0 π¬ 1 π 0
New study reveals how NCOA7-AS helps block flu virus entry by teaming up with V-ATPase and SNX5/6. Key mutations break this defense, offering new insight into how cells fight infection.
βοΈ M. Arnaud-Arnould, @arebendenne.bsky.social, @mickael-blaise.bsky.social, C. Goujon & coll.
π shorturl.at/q2uYb
03.04.2025 03:45 β π 1 π 0 π¬ 0 π 0
In the Thau lagoon, free-living amoebae show distinct habitat patterns and selective grazing on Vibrionaceae, new study reveals. A complex, underexplored microbial ecology!
βοΈ @gm-charriere.bsky.social & coll.
π shorturl.at/fWnuM
#MicroSky #MicrobialEcology #Protistology
03.04.2025 03:39 β π 2 π 1 π¬ 1 π 0
Another PhD Position in my lab - phage therapy - programming skill required. Open for international candidates
31.03.2025 14:03 β π 9 π 8 π¬ 1 π 1
New study shows HlyF/CprA enzymes enhance OMV-mediated virulence in E. coli and P. aeruginosa by promoting direct membrane fusion and clathrin-independent uptake.
A novel mechanism for efficient cargo delivery and host manipulation. #MicroSky
βοΈ @ericoswald.bsky.social & coll.
π shorturl.at/zpNYl
31.03.2025 04:46 β π 5 π 0 π¬ 0 π 0
New study reveals that E. coli LdcI filamentation under acid stress enhances pH buffering and fitness.
Disrupting polymerisation impairs enzyme clustering and stress response, highlighting self-assembly as a key regulatory mechanism. #MicroSky
βοΈ M. Kirchner, I. Gutsche & coll.
π shorturl.at/am3Pu
31.03.2025 04:36 β π 4 π 2 π¬ 0 π 0
Topics that span the microbial universe:
𧬠Pathogenesis
π± Food & Environmental Microbiology
π§ͺ Clinical & Sustainable Microbiology
π¦ Virology, Mycology, AMR, AI & more!
Donβt miss this meeting of minds in beautiful Bordeaux! π·
#SFM2025 #MicrobiologyCongress
28.03.2025 07:03 β π 2 π 1 π¬ 0 π 0
π€ A stellar speaker lineup awaits!
From @alainblanchard.bsky.social to @kimingeneva.bsky.social, @anne-puel.bsky.social, Mathieu Picardeau, and many more, world-class experts covering cutting-edge microbiology.
π£ Submit your abstracts for a chance to present!
#Science #Microbes
28.03.2025 07:03 β π 4 π 2 π¬ 1 π 0
π¨ Save the date!
The Annual Congress of the French Society for Microbiology is heading to Bordeaux, Sept 24β26, 2025!
An unmissable event for all microbe lovers.
π Full program here π shorturl.at/R1cwa
#SFM2025 #Microbiology #MicroSky
@sfmicrobiologie.bsky.social
28.03.2025 07:03 β π 6 π 2 π¬ 2 π 0
Topics that span the microbial universe:
𧬠Pathogenesis
π± Food & Environmental Microbiology
π§ͺ Clinical & Sustainable Microbiology
π¦ Virology, Mycology, AMR, AI & more!
Donβt miss this meeting of minds in beautiful Bordeaux! π·
#SFM2025 #MicrobiologyCongress
28.03.2025 07:00 β π 0 π 0 π¬ 0 π 0
#Microbiology #Genomics #MicroSky #Colorectalcancer
@pasteur.fr @institutcochin.bsky.social
04.03.2025 05:11 β π 1 π 0 π¬ 0 π 0
PhD in Microbiology,
Postdoctoral fellow - UCLouvain - LalouxLab
Prey - Predator interactions
#Bdellovibrio
Former in @LesterlinLab - #conjugation
ORCID : 0000-0003-0923-253X
A PhD student in the Cascales lab
PhD student at Enninga Lab - Institut Pasteur Paris | in-situ cryo electron tomography & Mtb π§«π¬
PhD in Microbiology and Molecular Biology - Open to work in international postdoctoral position
http://linkedin.com/in/chloΓ©-silard
PhD. PharmD. currently in Post-Doc in Bacterial Genome Plasticity unit, Institut Pasteur, Paris.
Genetics π§¬, plasmids, microbiology π¬ translation, Vibrio π¦
Understanding the pathogen phenotypic variations to decipher & control the infection process and the treatment failures
https://ciri.ens-lyon.fr/teams/persist
How the metabolic crosstalk between pathogenic bacteria and host cells impacts infection? @pasteur.fr
Microbiologist & RNA biologist, INRAE research director, professor at ENS-PSL
𧑠telling science stories, learning its history, sharing research approaches and findings in life sciences, exploring SciFi inspirations.
https://www.ibens.bio.ens.psl.eu/ida
Biology on Infection Unit at Institut Pasteur and Inserm
Research unit studying at the cellular and molecular levels how microbes propagate, cause disease and resist to drugs - CNRS-UniversitΓ© Lyon I - Lyon - France
Signaling and Asymmetry of the Bacterial cell lab at MMSB - CNRS Lyon
The Collaborative Research Centre DECIDE (DECisions in Infectious DisEases) aims to identify molecular mechanisms within the host that control the course of infectious diseases.
Professor at Montpellier University, IHPE Lab, France.
http://ihpe.univ-perp.fr/ihpe-charriere-guillaume/
Curious and interested in many aspects of phagocyte biology, vibrios, amoebae, oysters, host-pathogen co-evolution, and comparative immunology.
Relaying microbiology news, articles and comments relevant to aspects on bacteria, fungi, viruses and other microbes / microorganisms. Microbes are πͺ
Microbiologist at CNRS | Passionate about RNA, 'omics and Bacillus π»π§«π§¬π¬ | Based at Laboratoire de Chimie BactΓ©rienneπ©βπ¬| Soaking up the sun in MarseilleβοΈποΈ and its Calanquesππ₯Ύ| Echoes of my postdoc days in Scotland still lingerπΈπ₯ π΄σ §σ ’σ ³σ £σ ΄σ Ώ
Head of the Bacterial Commensalism and Pathogenesis team. Our research focuses on bacterial toxins, extracellular vesicles, and zoonotic pathogens, with a particular emphasis on Escherichia coli, Pseudomonas, Klebsiellaβ¦
