Emily Tsao's Avatar

Emily Tsao

@emilytsao.bsky.social

PhD candidate in the Hope lab at the University of Toronto | RNA binding protein and hematopoiesis enjoyer | she/her :)

59 Followers  |  105 Following  |  11 Posts  |  Joined: 18.11.2024
Posts Following

Posts by Emily Tsao (@emilytsao.bsky.social)

Preview
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging Efficient DNA repair might make possible the longevity of naked mole-rats. However, whether they have distinctive mechanisms to optimize functions of DNA repair suppressors is unclear. We find that na...

A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging | Science www.science.org/doi/10.1126/...

10.10.2025 11:05 β€” πŸ‘ 16    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
Post image

Excited to be in Kumamoto for #ISEH2025!! 🩸 I get to share my PhD work (so far) at poster #24 tomorrow and poster #3220 on Friday afternoon - please come by to chat about RNA binding proteins, erythropoiesis, and iron metabolism :)

23.09.2025 12:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
FlyBase:Contribute to FlyBase - FlyBase Wiki

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

15.08.2025 12:45 β€” πŸ‘ 130    πŸ” 159    πŸ’¬ 3    πŸ“Œ 26
Preview
GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells Red blood cell (RBC) membrane lipid peroxidation during blood bank storage profoundly impacts transfusion efficacy; however, the genetic determinants …

Iron-loaded Red Blood Cells undergo a lipid peroxidation process akin to ferroptosis during storage in the blood bank. We now show that they also harbor a functional GPX4, and common SNPs, genetic or pharmacological manipulation impact transfusion outcomes www.sciencedirect.com/science/arti...

14.08.2025 18:17 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
Preview
A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function - Nature Biotechnology RNA-binding motifs in eukaryotic proteins are presented in a comprehensive resource.

New in @natbiotech.nature.com: a team led by scientists at MSK and β€ͺUniversity of Toronto have developed a new platform to facilitate the study of RNA-biding proteins (RBPs) across hundreds of species of plants, insects, and animals.

28.07.2025 15:34 β€” πŸ‘ 43    πŸ” 17    πŸ’¬ 0    πŸ“Œ 3
Video thumbnail

UHN is grateful and honoured to have called Dr. James Till, one of the fathers of stem cell science, a valued member of TeamUHN.

His many colleagues and students continue their work in his legacy, furthering stem cell science and cancer research, and improving patient outcomes.

23.05.2025 18:26 β€” πŸ‘ 10    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

!!!

13.05.2025 22:44 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

WOOO!! πŸŽ‰πŸŽ‰πŸŽ‰ Congrats Steph!!

30.04.2025 17:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Thrilled to share the first pre-print from our lab! We tackled a big question: Why are some pediatric leukemias extremely aggressive? We explored the developmental origins of fusion-driven acute myeloid leukemia (AML). Let's dive in! #AML #NUP98 A thread... n/13

08.04.2025 14:31 β€” πŸ‘ 19    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1
Post image

What protects individuals from developing blood cancers?

Thrilled to share my work in @bloodgenes.bsky.social lab, describing inherited resilience protecting blood stem cells from clonal hematopoiesis by modifying RNA regulation. πŸ§΅πŸ‘‡ (1/n)
www.biorxiv.org/content/10.1...

27.03.2025 20:30 β€” πŸ‘ 46    πŸ” 12    πŸ’¬ 3    πŸ“Œ 2
Post image

Congratulations to our Senior Scientists Drs. John Dick and Jean Wang, and Jayne Danska from @sickkidsto.bsky.social
on receiving the Inventor of the Year Award @uhntoronto.bsky.social. Their research has advanced a cancer immunotherapy now in global Phase II trials for hematological malignancies.

21.03.2025 15:52 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 3    πŸ“Œ 1
Preview
Gordon Keller Receives the 2025 ISSCR Achievement Award for his Seminal Work in Regenerative Medicine β€” International Society for Stem Cell Research The International Society for Stem Cell Research (ISSCR) is honoring Gordon Keller, Ph.D., with this year’s ISSCR Achievement Award. Dr. Keller is the Director of the McEwen Stem Cell Institute at t...

Well deserved award for Dr. Gordon Keller! Gordon was a member of my thesis committee when I was a PhD student and his helpful suggestions made me a better scientist :)
www.isscr.org/isscr-news/g...

18.03.2025 16:15 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Had the best time in SLC learning lots about iron & heme last week!! So grateful for the fantastic program that the CIHD faculty & staff put together and to have met so many cool people :))

17.03.2025 18:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Cristiana O’Brien is our fourth #TeamUHNWomen feature and a doctoral student at @pmresearch-uhn.bsky.social.

Learn about why she is grateful to be in science and what it means to be a woman in her field ➑️ www.uhnresearch.ca/news/shining...

12.02.2025 21:03 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

So excited to visit Utah and listen to all these cool talks in March!!

12.02.2025 02:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Erasmus MC Hematology Lecture speaker lineup never fails to impress! #hemesky πŸ§ͺ🩸 mcusercontent.com/71bcc0f3bb8a...

11.01.2025 14:03 β€” πŸ‘ 25    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
Preview
Respiratory Research Lab @McMaster on LinkedIn: Are you ready to make a difference in asthma research? Your experiences… Are you ready to make a difference in asthma research? Your experiences could help shape the future of asthma treatments. Participants are financially…

Are you from #HamOnt or surrounding area? Have #asthma or wheezing during exercise? Want to take part in research at @mcmasteruniversity.bsky.social to discover new treatments ? Email asthma@mcmaster.ca to learn more! (Please share with yoru networks) #pulmsky www.linkedin.com/posts/macres...

01.01.2025 14:22 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Excited to share a major breakthrough from the lab! D&D-seq is a new technology that bridges a key gap in single-cell multi-omics/genomics : the ability to map DNA:Protein interactions (e.g., TFs or chromatin remodellers). Led by Ivan Raimondi, Wei-Yu Chi and Sang-Ho Yoon

02.01.2025 21:54 β€” πŸ‘ 71    πŸ” 11    πŸ’¬ 2    πŸ“Œ 3
Post image

Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology

www.biorxiv.org/content/10.1...

23.12.2024 17:49 β€” πŸ‘ 268    πŸ” 92    πŸ’¬ 6    πŸ“Œ 11
Post image

Bioart, courtesy of the NIH. All images are in the public domain and available for download as high-quality SVGs.
bioart.niaid.nih.gov

17.12.2024 01:15 β€” πŸ‘ 453    πŸ” 173    πŸ’¬ 14    πŸ“Œ 10

Oh rats! Thanks for letting me know - hopefully I can catch the next one if you visit again! :)

12.12.2024 00:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Hello! Would love to attend your talk (if it’s open to the wider UofT community/hasn’t already happened) - could I ask when/where it’s being hosted? :) Thank you!

11.12.2024 20:22 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Seated (online) and ready to listen!! πŸͺ‘

07.12.2024 17:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Safe travels!! And happy 60th to your dad! πŸŽ‚

26.11.2024 00:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes The CCR4-NOT complex is a major regulator of eukaryotic messenger RNA (mRNA) stability. Slow decoding during translation promotes association of CCR4-NOT with ribosomes, accelerating mRNA degradation....

I’m thrilled to share a collaborative story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu. We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation!
www.science.org/doi/10.1126/...

22.11.2024 18:09 β€” πŸ‘ 129    πŸ” 45    πŸ’¬ 3    πŸ“Œ 8

You as well!! πŸ«‚

23.11.2024 19:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

🚨 Save the Date!🚨 ISEH is heading to Kumamoto, Japan for #ISEH2025. Check out our confirmed speakers so far and mark your calendars for a great program you won't want to miss ➑️ iseh.org/iseh2025

20.11.2024 22:46 β€” πŸ‘ 26    πŸ” 15    πŸ’¬ 0    πŸ“Œ 2

Migrating! Happy to see lots of favourite blood folks already here :)

19.11.2024 00:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0