Brittany Moyce Gruber, PhD

🧵(1/7)We are now out of September🍁! From the last two weeks we have had publications from the CIRTN labs of Drs Jenny Bruin, Mourad Ferdaoussi, Peter Light, Patrick MacDonald, James Shapiro and Bruce Verchere!

📢 We’re hiring a Lab Manager for the MILC Biorepository!

Join our #THRiVElab team to advance science on #breastfeeding and #humanmilk.

📍 In person, full-time in Winnipeg
💵 $51K–$74K + benefits
🧪 5+ yrs experience
🔗 Apply: viprecprod.ad.umanitoba.ca – #39591

Pls share! 💫
#JobAlert #ScienceJobs

Come work with us and make great science happen with awesome people! 🧫🥼👩🏾‍💻🤜🏻🤛🏽

Kupffer cell programming by maternal obesity triggers fatty liver disease Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

Maternal obesity rewires fetal Kupffer cells (KCs) via HIF1α, triggering fatty liver disease in adult mice. Replacing KCs with naive monocytes rescues the liver. Great @nature.com paper from the great @masslab.bsky.social. 🤗
doi.org/10.1038/s415... 🧪

🚨 BREAKING: Nearly 4 months the NIH cut its first grants, a judge has ruled that the directives and process that led to cuts are arbitrary and capricious.

"The explanations are bereft of reasoning — virtually in their entirety... unsupported by [facts]."

Each of them are VOID and ILLEGAL, he says.

The intriguing case for GIPR antagonism, supported by genetics, pharmacology and Maritide is presented by Rosenkilde, George, Veniant and Holst #weightloss ##obesity diabetesjournals.org/diabetes/art...

As we head to the 2025 @amdiabetesassn.bsky.social GIP biology will be part of the conversation. Here Samms and Sloop summarize the compelling scientific story of Tirzepatide and the case for GIPR co-agonism #Diabetes #Weightloss #obesity diabetesjournals.org/diabetes/art...

Manitoba Wildfires Response 2025

My family in Flin Flon have safely evacuated, but thousands are trapped in pukatawagan.
Govt will match red cross donations, as heroic efforts in apocalyptic conditions continue.
Please consider a donation
#manitobawildfire
www.redcross.ca/how-we-help/...

Today the Supreme Court cleared the way for the federal government to transfer thousands of acres of national forestland including a Native American sacred site, to Resolution Copper a mining company owned by Rio Tinto and BHP. The land holds deep spiritual significance for the Western Apache tribe.

This also includes resident and fellow physicians

NSF’s grant cuts fall heaviest on scientists from underrepresented groups Projects to broaden participation were cut disproportionately—and were often led by Black scientists, women, and those with disabilities

Numbers are stark. www.science.org/content/arti...

Pedants: actually, AI doesn't use that much water compared to farming

Wise people: literally a single drop of water spent on the Plagiarism Machine That Lies is one drop too many

Donate to Standing with Travis Stewart, organized by Meghan Adams A Husband, Father, and Hero Facing Stage 4 Cancer On April 17, 2025 the stable, predict… Meghan Adams needs your support for Standing with Travis Stewart

My cousin's husband was diagnosed with stage 4, metastatic colorectal cancer.
They have 2 young children and a beautiful life together.

Please consider a donation AND get screened regularly
gofund.me/62c647cb

Gusting winds worsen wildfire near The Pas, creating 'really big beast' and forcing more evacuations | CBC News A Manitoba wildfire threatening various communities over the past week was intensified by strong winds overnight, forcing hundreds more people to evacuate.

Gusting winds worsen wildfire near The Pas, creating 'really big beast' and forcing more evacuations

www.cbc.ca/news/canada/...

Bill Gates accuses Elon Musk of ‘killing’ children with USAID cuts Billionaire reopens feud with Tesla chief as he unveils plan to spend $200bn on philanthropy and close foundation in 2045

Billionaire philanthropist Bill Gates ratcheted up his feud with Elon Musk, accusing the world’s richest man of “killing the world’s poorest children” through what he said were misguided cuts to US development assistance

www.ft.com/content/bdd9...

Measles in Alberta for 2025-05-06:
• 287 cases (+22)
• +1 north zone
• +4 central zone
• +17 south zone

We are now nearly double what the total national number of Canadian cases was in 2024, just in Alberta.

Effective May 5, 2025, NOAA’s National Centers for Environmental Information (NCEI) will decommission its snow and ice data products from the Coasts, Oceans, and Geophysics Science Division (COGS). As a result, the level of services for affected products below will be reduced to Basic—meaning they will remain accessible but may not be actively maintained, updated, or fully supported. This includes Sea Ice Index, Snow Data Assimilation System (SNODAS) Data Products, Glacier Photograph Collection, U.S. National Ice Center Arctic Sea Ice Charts and Climatologies in Gridded Format Gridded Monthly Sea Ice Extent and Concentration, 1850 Onward World Glacier Inventory. If you rely on these products in your work, research, education, or planning, we invite you to share your story at nsidc@nsidc.org. Your input can help us demonstrate the importance of these data sets and advocate for future support.

This is horrible. I don't even know what to say. Some of our most key polar data.

"As a result, the level of services for affected products below will be reduced to Basic—meaning they will remain accessible but may not be actively maintained, updated, or fully supported."

nsidc.org/data/user-re...

National Institutes of Health lays off hundreds more staff, including at cancer research institute The cuts at the National Institutes of Health blindsided staff, after reassurances that no further layoffs were planned.

More firings at the National Cancer Institute, including the Cancer Information Service, “which provides answers to doctors and patients about cancer, and updates to databases summarizing cancer information for healthcare providers”.

I mean who needs it, right?

www.cbsnews.com/news/nih-lay...

Which FDA-approved vaccines had randomized, placebo-controlled trials?

ALL OF THEM.

Polio?
Measles, mumps, rubella?
Haemophilus influenzae B?
Diphtheria, tetanus, pertussis?
Meningococcus?
Varicella?
Pneumococcus?
Rotavirus?
RSV?
Hepatitis B?
Influenza?
HPV?
COVID-19?
Shingles?

YEP.

A thread🧵
1/

I think this is a Peppa Pig plot

Cole Perfetti (59:57) scores the latest game-tying goal in a Game 7 in NHL history!

Exclusive: NSF stops awarding new grants and funding existing ones US science funder also plans to screen grant applications for compliance with ‘agency priorities’.

Staff members at the US National Science Foundation (NSF) were told on 30 April to “stop awarding all funding actions until further notice,” according to an email seen by Nature.

https://go.nature.com/44Ugf9V

a close up of a statue of yoda smoking a cigarette and saying `` learning am i '' . Alt: a close up of a statue of yoda smoking a cigarette and saying `` learning am i '' .

Any peds nephrology or ID folks have a good lecture on measles in immunocompromised patients you’d like to give our group? Worried that the outbreak will spread to MN soon and want to be prepared.

Seriously, Anna Lambe is so good she makes Siaja one of the most instantly lovable characters ever.

youtu.be/xz2ty6KGBSg

I congratulate Prime Minister Mark Carney and the Liberal Party on their success in Canada’s election.  I’m confident Mark will be a strong leader for the fundamental values and interests Canadians and Americans share.

Thank you Joe Biden!

If you’re in line when the polls close, stay in line. You can still cast your ballot. Your vote matters.