MSAID

It' a wrap at #HUPO2025 in Toronto! Thank you to everyone who stopped by Booth #403, we cherished the scientific exchange and look forward to collaborating on advancing proteomics in the "one-health era". Safe travels everyone! #HUPO2025 #TeamMassSpec #Proteomics

#HUPO2025 Day 3! In focus: Poster Session 3 (1:15-3:15 PM) and our contribution “Spectrum-centric analysis of timsTOF data with CHIMERYS”. Drop in at the poster or Booth #403. #HUPO2025

Good morning Toronto! “On Day 2 Florian presents in Poster Session 2 (1:15-3:15 PM): “A universal search algorithm for bottom-up proteomics” – an intelligent search algorithm that deconvolutes chimeric fragmentation spectra across DDA, DIA and PRM workflows. Make sure to stop by. #HUPO2025”

Good morning Toronto! Today at #HUPO2025 Poster Session 1 (1:15-3:15 PM) we are presenting “A scalable, cloud-based proteomics platform for the masses”. Stop by Alex' poster or Booth #403 or drop a line if you’re curious about large-scale reproducible proteomics. #TeamMassSpec

Thrilled to be attending #HUPO2025 in Toronto! Visit us at Booth #403, where we’ll be presenting the newest updates to our proteomics platform and unveiling CHIMERYS 5. We can’t wait to engage with all of you. #Proteomics #TeamMassSpec

Last day at #ASMS2025! Don’t miss our talk today, featuring the MSAID Platform — a scalable, cloud-based solution designed for bottom-up proteomics.

📅 June 5 | 3:30–3:50pm | Hall AB
🔗 www.msaid.de/conferences/...

#TeamMassSpec #TeamProteomics #Proteomics #MassSpectrometry

We're off to our poster session at #ASMS2025! Join us at posters TP504 and TP507 to hear about our spectrum-centric analysis of timsTOF data and the latest updates on CHIMERYS, a universal search algorithm for bottom-up proteomics.

#TeamProteomics #TeamMassSpec #Proteomics #MassSpectrometry

Good morning #ASMS2025! See you soon in Room 322 at the Baltimore Convention Center for our breakfast seminar. We look forward to seeing you there!

#TeamProteomics #TeamMassSpec #Proteomics #MassSpectrometry

Hello #ASMS2025! Get ready for two exciting presentations from our team in Baltimore — happening tomorrow!

🔗 msaid.de/conferences/...
📍 Stop by Booth #203

#TeamMassSpec #TeamProteomics #Proteomics #MassSpectrometry

Join us tomorrow morning for a Breakfast Seminar at #ASMS2025 and get a first look at the latest updates to CHIMERYS 5 and the MSAID Platform.

🔗 Save your spot here: msaid.de/conferences/...

#TeamProteomics #TeamMassSpec #Proteomics #MassSpectrometry

Do not miss our talk next Thursday at #ASMS2025 on the MSAID Platform—a scalable, cloud-based solution for bottom-up proteomics.

📅 June 5 | 3:30–3:50pm | Hall AB
🔗 www.msaid.de/conferences/...

#TeamMassSpec #TeamProteomics #Proteomics #MassSpectrometry

Are you attending #ASMS2025? Don’t miss our talk on Double Dipping: Confirmation Bias Inflates DIA Data Completeness, revealing how two-pass searches and sample-specific spectral libraries can overstate data completeness and affect FDR control.

🔗 www.msaid.de/conferences/...

#TeamMassSpec

Only one week left for #ASMS2025! Join us for our talk on accurate and fast zero-shot peptide spectrum prediction, featuring a deep learning approach that predicts fragment ion intensities—even for peptides with unseen post-translational modifications.

🔗 www.msaid.de/conferences/...

#TeamMassSpec

Take a look at the scientific posters we will showcase at #ASMS2025, featuring our cutting-edge research:

🔗 Learn more: www.msaid.de/conferences/...

📍 Make sure to visit us at Booth #203

#TeamMassSpec #TeamProteomics #Proteomics #MassSpectrometry

Only 2 weeks until #ASMS2025 in Baltimore! Don’t miss the exciting talks our team will present during the conference.

🔗 Read more: msaid.de/conferences/...

📍Visit us at Booth 203—our team looks forward to connecting and engaging in insightful scientific discussions!

#TeamMassSpec #TeamProteomics

We are excited to announce that MSAID's Information Security Management System (ISMS) was recently certified according to ISO/IEC 27001:2022 by TÜV SÜD! Achieving this milestone highlights our commitment to meet rigorous standards for information security.🔒

#ISO27001 #TÜVSüd #DataSecurity #AI

Join us for our Breakfast Seminar at #ASMS2025 and discover the latest updates to CHIMERYS 5 and the MSAID Platform. Learn about new features and hear real-world applications from fellow scientists who are using our technology in their research.

🔗 Register here: www.msaid.de/conferences/...

Calling all #TeamMassSpec enthusiasts! 🚀 Join us this June at #ASMS2025 in Baltimore. Visit us at booth #203 and do not miss our breakfast seminar, where we will unveil the latest MSAID Platform updates and launch CHIMERYS 5.

🔗Register here:
www.msaid.de/conferences/...

#TeamProteomics #Proteomics

🔄 Fig 6: CHIMERYS enables fair DDA vs DIA comparisons.
→ Same algorithm, consistent FDR
→ IDs vs data completeness: tune your workflow to your needs
Unify your data analysis workflow with #CHIMERYS: choose the mode, not the model!
7/7

💡 Fig 5: CHIMERYS unlocks #directInfusion proteomics (DISPA) — library-free!
→ Up to 3× more IDs result in richer functional insights
→ Same #deepLearning model and data processing as for DDA & DIA
Any mass spec-data, no special tuning, just deeper results.
6/7

📐 Fig 4: CHIMERYS quantifies peptides directly from chimeric #MS2 spectra. How? Deconvolution!
→ #PRM-level precision with r = 0.99 vs Skyline
→ CV performance on par with established DIA algorithms
No libraries. No manual curation. Straight from data to insights.
5/7

🚀 Fig 3: In DIA, complexity skyrockets. No problem for CHIMERYS!
→ CHIMERYS delivers high ID rates with better FDR control than other solutions
→ More informative fragment utilization yields more reliable #quantification
It handles #DIA data in a spectrum-centric fashion.
4/7

📈 Fig 2: Challenging data? CHIMERYS shines!
Extract more IDs from any DDA data — good for revisiting legacy data, even low-res.
→ 4x more throughput without loss in IDs
→ 2x more IDs at the same throughput
→ Cloud-based for speed & scalability
Unveil secrets older data hold!
3/7

🧩 Fig 1: CHIMERYS solves the puzzle of chimeric spectra as mixtures of peptides.
Using AI-based predictions and regularized linear regression, it identifies multiple peptides per MS2 spectrum. With rigorous #FDR control, it outperforms 8 search engines in #DDA ID rates.
2/7

🚨 New in @naturemethods.bsky.social
#CHIMERYS has already transformed #proteomics since 2022, powering DDA, DIA & PRM analysis in a single workflow.
Wanna know how CHIMERYS works? 👉 www.nature.com/articles/s41...
#TeamMassSpec #NatureMethods #ASMS2025 🧪🔬
1/7

🔄 Fig 6: CHIMERYS enables fair DDA vs DIA comparisons.
→ Same algorithm, consistent FDR
→ IDs vs data completeness: tune your workflow to your needs
Unify your data analysis workflow with #CHIMERYS: choose the mode, not the model!

💡 Fig 5: CHIMERYS unlocks #directInfusion proteomics (DISPA) — library-free!
→ Up to 3× more IDs result in richer functional insights
→ Same #deepLearning model and data processing as for DDA & DIA
Any mass spec-data, no special tuning, just deeper results.

📐 Fig 4: CHIMERYS quantifies peptides directly from chimeric #MS2 spectra. How? Deconvolution!
→ #PRM-level precision with r = 0.99 vs Skyline
→ CV performance on par with established DIA algorithms
No libraries. No manual curation. Straight from data to insights.

🚀 Fig 3: In DIA, complexity skyrockets. No problem for CHIMERYS!
→ CHIMERYS delivers high ID rates with better FDR control than other solutions
→ More informative fragment utilization yields more reliable #quantification
It handles #DIA data in a spectrum-centric fashion.

📈 Fig 2: Challenging data? CHIMERYS shines!
Extract more IDs from any DDA data — good for revisiting legacy data, even low-res.
→ 4x more throughput without loss in IDs
→ 2x more IDs at the same throughput
→ Cloud-based for speed & scalability
Unveil secrets older data hold!