Scientists are loving our latest study! 🎉
Thrilled that our @elife.bsky.social research article on RAD51 filament strand exchange is August’s most-read in Structural Biology. A landmark for understanding DNA repair. 🧬
23.09.2025 09:12 — 👍 11 🔁 2 💬 0 📌 0
Cryogenic electron microscopy has been used to determine the detailed structure of an intermediate state called a “D-loop” that forms when strands of DNA are exchanged during homologous recombination.
buff.ly/ofD02RD
24.08.2025 08:21 — 👍 28 🔁 7 💬 0 📌 0
Huge thanks to the incredible team. This was a massive effort, and I’m so proud of what we achieved together! now in @elife.bsky.social: Structural mechanism of strand exchange by the RAD51 filament doi.org/10.7554/eLif...
26.08.2025 10:51 — 👍 7 🔁 2 💬 0 📌 0
Thank you to everyone who joined us for the PaCIFiC launch, and for the strong interest from researchers across Cambridge.
This milestone reflects a shared vision to expand cryo-imaging across disciplines.
@campathology.bsky.social @cambridgebiosci.bsky.social
www.path.cam.ac.uk/news/pacific...
28.05.2025 13:48 — 👍 4 🔁 0 💬 0 📌 0
Have seen firsthand the many years of sweat and smarts that have gone into this work.
Categorized as a "landmark" study by @elife.bsky.social
Congratulations @luayjoudeh.bsky.social and @robertappleby.bsky.social !
27.05.2025 14:24 — 👍 10 🔁 2 💬 1 📌 0
CryoEM structure of a RAD51 synaptic filament. Glass ribbons of RAD51 protein bind to three fluorescent DNA strands
Our latest paper describing the #cryoEM structure of the human RAD51 synaptic complex is now out with accompanying peer review in eLife - a landmark study according to the editors!
elifesciences.org/reviewed-pre...
27.05.2025 14:15 — 👍 4 🔁 2 💬 0 📌 1
RAD51 D-loop
🧬 Thrilled to share that our latest work, A landmark study uncovering intricate molecular details of the human DNA repair process.
📰 Press release: elifesciences.org/for-the-pres...
📄 Full article: elifesciences.org/reviewed-pre...
Proud of the team #DNADamage #CryoEM #CambridgeUniversity
27.05.2025 14:08 — 👍 5 🔁 2 💬 0 📌 1
Seminar on Protein Structure Evolution every 2nd Tue, 4 PM GMT.
Link: https://tinyurl.com/prose-seminar2
By @claudiaalcar.bsky.social @caro-rocha.bsky.social @lacholt.bsky.social @zachary-ardern.bsky.social @romeritos.bsky.social @hassanzaman.bsky.social
Hi 👋 I'm a postdoc in the #Neuroimmunology and #Imaging group at the @dzne.science Bonn 🧪🔬 Passionate about #ComputationalNeuroscience 🧠💻 and #NeuralModeling 🧮
🌍 fabriziomusacchio.com
👨💻 github.com/FabrizioMusacchio
🐘 sigmoid.social/@pixeltracker
H2A.Z is cool
Horses are bad at existing
PhD student in the Sanulli Lab at Stanford University
We study chromosomal replication & recombinational repair mechanisms, Smc5/6, SUMO-based controls using multidisciplinary approaches. Tweets are a group effort.
Associate Professor at MIT BE : http://ashansenlab.com
Interested in understanding the relationship between 3D genome structure and function
spinster (in multiple ways) | she/her | comp bio phd/data vis | crochet | audhd | ace | queer | fat | pgh | fairy-type | dnd/lancer | stardew/fields of mistria | tng/ds9/voy | I do science for money, but I nerd for free
Genomics, bioinformatics; attempting to say useful things about cancer and evolution.
Institute of Genetics and Cancer, University of Edinburgh
https://institute-genetics-cancer.ed.ac.uk
https://semplelab.com
Molecular evolution of cell morphology and growth mechanisms in alphaproteobacteria 👾 Assoc Prof of Biology at The U of Scranton 🥟
Simons Fdtn. LSRF postdoc fellow in @ctmurphy1.bsky.social lab at Princeton University | Aging, death, and DNA repair in worms 🪱 🏳️🌈 | ♥️ art and film https://letterboxd.com/deelort/films/
Protein structure evolution | Royal Society Newton International Fellow at UCL | she/her
Chasing DNA double strand break repair outcomes and clastogen response
https://scholar.google.com/citations?user=JZpgwJwAAAAJ&hl=en
chem bio PhD student in the Doudna Lab @Berkeley
Principal Group Leader at the Francis Crick Institute. DNA replication, cryo-EM and molecular mechanism.
Group leader.
HGT in bacterial pathogens. Acinetobacter, Legionella. Natural transformation. AMR. MGEs.
Centre International de Recherche en Infectiologie
Professor, TALENted & CRISPRing Genome Editor, maker of low-allergenic, low-toxic, pathogen-free food crops, cat-lover
Interested in treating/preventing age-related ill health (dementia, cardiovascular disease, cancer, frailty, etc.) by targeting aspects of the biology of aging. Learn more: https://www.c-span.org/video/?511443-1/ageless
Thompson Lab at Lyon College 🧬🧬🧬
Studying helicases, conjugative transfer, and genomics!
Cell biologist and a cat person. I mainly study CDK8/19, cell cycle regulation, and new anti-cancer drug candidates.
https://orcid.org/0000-0002-9080-5683
