Thiago Bruder

Thanks @spjuraschek.bsky.social for sharing! I’m very honored!

Many thanks @krispy-ed.bsky.social !!!

Huge thanks to @Drshubhnita for her incredible work & contributions to our lab's growth! 👏 @ahascience.bsky.social @ahajournals.bsky.social. #PGRN #vascularscience #mitochondria #AHA

Progranulin Maintains Blood Pressure and Vascular Tone Dependent on EphrinA2 and Sortilin1 Receptors and Endothelial Nitric Oxide Synthase Activation | Journal of the American Heart Association

What's surprising? Unlike small vessels, PGRN deficiency reduces vascular contractility in large vessels (aorta). Why? We're still exploring! 🤔 Previously, we showed that a lack of PGRN increases vascular response in resistance artery. www.ahajournals.org/doi/10.1161/...

Vascular Contractility Relies on Integrity of Progranulin Pathway: Insights Into Mitochondrial Function | Journal of the American Heart Association

Thrilled to share our latest paper published in @ahajournals.bsky.social ! 🎉 Led by our former grad student
@Drshubhnita. We show how progranulin (PGRN) regulates vascular tone in large vessels (aorta) by controlling mitochondrial dynamics & respiration. www.ahajournals.org/doi/10.1161/...

I’m here as well