@mashaals.bsky.social
@madmaxolotl.bsky.social
@scientist-ninja.bsky.social
Brenda
Claudia
@acflewis.bsky.social
@stairwaytokevin.bsky.social
@tinalasisi.bsky.social
Arslan Zaidi

This research involved researchers from different disciplines and nationalities who collaborated from various parts of the world:

11/ If you are interested in genetics or want to challenge old assumptions, check it out! 🌍🔍

End of thread.
What do you think about this new form of analysis?

10/ This research is the result of a CONAHCYT Mx🧑‍🔬 grant and it received a Graduate Student Excellence Award🏆 by the SMBE🧬 this year✨

GitHub - mariajpalma/GG-NC: Here is the code for the Pipeline and shiny app, also the wrapper to run it Here is the code for the Pipeline and shiny app, also the wrapper to run it - mariajpalma/GG-NC

9/ This approach highlights the richness of genetic connections and how demographic and evolutionary events have shaped human genetic makeup.🧠✨
You can apply it to any genetic data using: github.com/mariajpalma/...

8/ Our method does not seek an absolute genetic truth. Instead, it recognizes that genetic relationships are contextual and vary depending on the research questions and markers analyzed.🧬💡

7/ For example, using the network-based approach, we found between 5 and 34 genetic communities in one analysis, and the number of communities depends on the metrics and resolutions applied. This challenges the idea of ​​universal categorizations.🚫📦

6/ We applied this approach to a dataset combining information from the 1000 Genomes and Human Genome Diversity Projects. The results? A much richer and more detailed view of human genetic diversity.🌍

5/ Unlike traditional methods, our tool does not group individuals into a fixed number of predefined categories. Instead, it identifies genetic communities at different levels of resolution using clustering algorithms, such as Louvain and Leiden.🧑‍💻👥

4/ We have developed a network-based pipeline and visualization tool that diverges from conventional genetic analysis models. This approach, grounded in relational thinking, builds individual networks utilizing genetic similarity metrics.💡🧬
sohail-lab.shinyapps.io/GG-NC/

Counter the weaponization of genetics research by extremists Geneticists must rethink how they conduct their research and how they communicate results.

3/Read this article on this topic: “Counter the weaponization of genetics research by extremists”
www.nature.com/articles/d41...
See, also:
▶️
pubmed.ncbi.nlm.nih.gov/36989389/
▶️
muse.jhu.edu/article/894253

2/ Genetic studies have been misused to rationalize hate speech. Rethinking the way we group individuals in our research sends the message that we acknowledge that continental groups–or other rigid classifications–fail to capture human genetic diversity.

1/ Human genetics has traditionally been framed and studied using approaches that assume discrete, unchanging clusters such as continental groups🗺️. But what if this oversimplifies complex genetic relationships and co-produces racial frameworks?🤔

🧵Thread: Is it time to rethink human genetic diversity through the lens of relational thinking?🌍🧬

The multi-scale complexity of human genetic variation beyond continental groups Traditional clustering and visualization approaches in human genetics often operate under frameworks that assume inherent, discrete groupings1,2. These methods can inadvertently simplify multifaceted ...

I am proud to share our latest paper📜 “The multi-scale complexity of human genetic variation beyond continental groups”, just pre-printed on @biorxivpreprint.bsky.social !

Link Here ➡️ www.biorxiv.org/content/10.1...

@mashaals.bsky.social
@scientist-ninja.bsky.social
@madmaxolotl.bsky.social
Brenda
Claudia
@acflewis.bsky.social
@stairwaytokevin.bsky.social
@tinalasisi.bsky.social
Arslan Zaidi

This research involved researchers from different disciplines and nationalities who collaborated from various parts of the world:

11/ If you are interested in genetics or want to challenge old assumptions, check it out! 🌍🔍

End of thread.
What do you think about this new form of analysis?

10/ This research is the result of a @Conahcyt_Mex🇲🇽🧑‍🔬 grant and it received a Graduate Student Excellence Award🏆 by the @OfficialSMBE🧬 this year✨
x.com/OfficialSMBE...

GitHub - mariajpalma/GG-NC: Here is the code for the Pipeline and shiny app, also the wrapper to run it Here is the code for the Pipeline and shiny app, also the wrapper to run it - mariajpalma/GG-NC

9/ This approach highlights the richness of genetic connections and how demographic and evolutionary events have shaped human genetic makeup.🧠✨
You can apply it to any genetic data using: github.com/mariajpalma/...

8/ Our method does not seek an absolute genetic truth. Instead, it recognizes that genetic relationships are contextual and vary depending on the research questions and markers analyzed.🧬💡

7/ For example, using the network-based approach, we found between 5 and 34 genetic communities in one analysis, and the number of communities depends on the metrics and resolutions applied. This challenges the idea of ​​universal categorizations.🚫📦

6/ We applied this approach to a dataset combining information from the 1000 Genomes and Human Genome Diversity Projects. The results? A much richer and more detailed view of human genetic diversity.🌍

5/ Unlike traditional methods, our tool does not group individuals into a fixed number of predefined categories. Instead, it identifies genetic communities at different levels of resolution using clustering algorithms, such as Louvain and Leiden.🧑‍💻👥

4/ We have developed a network-based pipeline and visualization tool that diverges from conventional genetic analysis models. This approach, grounded in relational thinking, builds individual networks utilizing genetic similarity metrics.💡🧬
sohail-lab.shinyapps.io/GG-NC/

Counter the weaponization of genetics research by extremists Geneticists must rethink how they conduct their research and how they communicate results.

3/Read this article on this topic: “Counter the weaponization of genetics research by extremists”
www.nature.com/articles/d41...
See, also:
▶️https://pubmed.ncbi.nlm.nih.gov/36989389/
▶️https://muse.jhu.edu/article/894253

2/ Genetic studies have been misused to rationalize hate speech. Rethinking the way we group individuals in our research sends the message that we acknowledge that continental groups–or other rigid classifications–fail to capture human genetic diversity.

1/ Human genetics has traditionally been framed and studied using approaches that assume discrete, unchanging clusters such as continental groups🗺️. But what if this oversimplifies complex genetic relationships and co-produces racial frameworks?🤔

🧵Thread: Is it time to rethink human genetic diversity through the lens of relational thinking?🌍🧬