Gavin Boothroyd

A @pacbio.bsky.social high quality HiFi genome is now £315 with our new SPRQ-Nx chemistry.

As @genomicsuk.bsky.social said “complete genomes at a completely new price” Stop by booth 165 at #FOG26 to discuss how you can be part of this exciting new chapter for genomics

#wgs #genomics

The @molecularanalysis.bsky.social Team are hosting a @pacbio.bsky.social launch event for our new #Vega long read instrument, great attendance and fantastic talks from an introduction to the technologies involved, to research taking place already within the University and from further afield!

Looking forward to being part of this!

Poster with an image of a PacBio Vega instrument, and the text: Molecular Analysis; New Technology; PacBio Vega Long Read Sequencing; Genome Assembly: Novel strains CpG methylation Metagenomics: Species and strain resolution Transcriptomics: de novo assembly Differential splicing

We are very excited to offer PacBio Long Read Sequencing in @molecularanalysis.bsky.social !
If you are interested, please get in touch: www.gla.ac.uk/colleges/mvl...
You can also save the date - 14 Nov - as we will be hosting reps from PacBio. More details to follow!

Nice cloud inversion from the top of Ben Lomond yesterday

With the insights it brings, at $300 why would you chose any other genome over a HiFi genome?

Identification of de novo variants from parent-proband duos via long-read sequencing While de novo variants cause many Mendelian disorders, their detection currently requires sequencing of the proband and both biological parents. This is not feasible when only one parent is available,...

Looking forward to presenting duoNovo at ASHG this week.

We use long-read sequencing to detect de novo variants without having to sequence both parents. It's conceptually straightforward, and performs very accurately among variants likely to be clinically relevant.

www.medrxiv.org/content/10.1...

Folk music fan. Principal Clinical Scientist. Meet David Gokhale – leading the first-ever #Vega install in the UK (and the first in an NHS lab). His take? "It was clear this was a system we were eager to get our hands on.”

Soon, you’ll understand why we’re saying #TheresHiFiForThat
bit.ly/3IWVuS1

The @pacbio.bsky.social team are excited to be working with you! Looking forward to seeing how we can help advance research in lots of different areas with our #hifireads

Power washing his driveway on Monday to second top of the bill at Glastonbury on Friday #rockstarneighbours

#microbiome folks, here’s your chance to get free highly accurate #longread sequencing for your #metagenomics research. We’re accepting applications until 7/18. Link to apply and more information in post below.
Thanks to our sequencing sponsors @seqcenter.bsky.social and @zymoresearch.bsky.social.

PureTarget from #PacBio delivers scalable, accurate repeat expansion analysis with full sequence resolution. See how #HiFiSequencing enables a single assay to streamline complex testing across over a dozen genes.

Watch now: bit.ly/4jYhzMO

#PrecisionWithHiFi

PureTarget from #PacBio is a PCR-free Cas9 method that preserves methylation and reduces GC and size bias. Sequence expanded alleles, target complex regions, and multiplex up to 48 samples on Revio or Vega.

Watch now: bit.ly/4kWWoMg

#PrecisionWithHiFi

An absolute joy seeing Pulp lastnight for the first time since the 1990s. They’ve still got it

Exciting updates on @pacbio.bsky.social #PureTarget panels announced by @sarahdoom.bsky.social at #ESHG2025. An expanded repeat expansion panel and a carrier screening panel are coming very soon. If you are at the conference come and visit the #PacBio booth to find out more!

ESHG has been really fun so far. Check out the PacBio satellite symposium tomorrow where I’ll be talking about what’s coming next with PureTarget. 14:15 in Amber 5-6. We’re about more than just the best party.

Good morning #ESHG2025 come and join the @pacbio.bsky.social symposium this afternoon in Amber 5+6 between 14:15-15:45. We have a great line up of customer speakers and some exciting new product news! Hope to see you there!

Day 3 at the @microbiologysociety.org conference and it’s @pacbio.bsky.social symposium day!

📍 Join @jewilki.bsky.social and guest speaker @yanshao.bsky.social, @sangerinstitute.bsky.social at 13:15-13:45 to find out more

Legendary PacBio 🧦 will be available for all attendees! #Microbio25

Day 2 of the @microbiologysociety.org conference in Liverpool, drop by the @pacbio.bsky.social booth to chat all things microbial genomics, get a demo of our new #Vega platform and find out how #HiFisequencing is redefining research for all applications and budgets!

#vega #microbiome #microbio25

Come and meet the @pacbio.bsky.social team and #Vega at @microbiologysociety.org conference! #microbio25

Alexander Hoischen from @radboudumc.bsky.social presented impressive work demonstrating how PacBio HiFi reads aid in diagnosing rare diseases. Further, his work offers potential for diagnosing more patients in future. As someone who also works on a rare disease, this is truly inspiring! #rngs25

With the new #SPRQ chemistry, #PacBio users are achieving higher accuracy for all variant types, robust yields from 4x lower input amounts, and consistently superior performance over previous chemistry. See how it’s setting a new standard in long-read sequencing.

Learn more: bit.ly/3Y0Ds6Z

Really looking forward to attending @microbiologysociety.org annual meeting in Liverpool. As well as a great @pacbio.bsky.social symposium with talks from @jewilki.bsky.social and @yanshao.bsky.social we will have the #Vega system on booth so please stop past for a demo #MicroBio25

Datasets - PacBio - Highly accurate long-read sequencing Explore these publicly available datasets generated using SMRT Sequencing applications including whole genome sequencing, RNA sequencing, and more.

I didn't know PacBio maintained its own curation of sample/reference datasets. Saves me a bit of trouble of hunting down reliable ones for a pipeline testing:

www.pacb.com/connect/data...

Our contribution to sequencing and genomics BBSRC’s investments into the tools underpinning genome sequencing and wider genomics research has supported innovation and expansion of this bioscience field.

📢 Exciting news! @BBSRC’s latest report highlights @EdGenomics' pivotal role in advancing UK genomics & sequencing! We’re honoured to be featured. 🧬🙌

📰 Read more: www.ukri.org/who-we-are/h...

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Join #PacBio at #AGBT25 to explore the latest in HiFi sequencing with our new benchtop sequencer Vega, new applications like Ampli-Fi and Sci-Fi, and advancements in SPRQ chemistry. Stop by to connect, learn, and see what’s next in sequencing. #AGBT2025

Evaluating the efficiency of 16S-ITS-23S operon sequencing for species level resolution in microbial communities - Scientific Reports Scientific Reports - Evaluating the efficiency of 16S-ITS-23S operon sequencing for species level resolution in microbial communities

“V3-V4 #16S rRNA sequencing was sufficient for genus-level analysis. However, V3-V4 sequencing was shown to perform poorly at the species-level, this study demonstrates using full rRNA operon (16S-ITS-23S) sequencing performs much better at this level.” #PacBio 🧵 1/3
www.nature.com/articles/s41...

Great soil #metagenomics talk by @mikeschatz.bsky.social.

Few reads can be classified because everything is novel... so just build the reference catalogue first!

Hundreds of high-quality MAGs being recovered with #PacBio HiFi, and new sequencing with Vega is on par with quality from Revio.

NEW: GutID, the first commercial human gut health test powered by HiFi sequencing, sets a new benchmark in gut microbiome testing. Learn how this transformative tool leverages #PacBio tech to open new frontiers in #healthcare by providing deeper insights into the human #microbiome. bit.ly/3CfmGIF

Join us at PAG 2025 to see how PacBio #HiFisequencing is advancing research in plant and animal sciences. Learn how this technology is tackling global challenges like conservation and sustainability for a brighter future. 

Details: bit.ly/41hR9Qw  

#PacBio #PAG32