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Adrian Duszkiewicz

@adrian-du.bsky.social

Systems neuroscientist | Working out how the 🧠 generates 🌐 to find its 🧭 | Lecturer (Asst Prof) at the University of Manchester | Big fan of ancient things πŸΊπŸ“œ

251 Followers  |  479 Following  |  57 Posts  |  Joined: 21.06.2025
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Posts by Adrian Duszkiewicz (@adrian-du.bsky.social)

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Recurrent cortical networks encode natural sensory statistics via sequence filtering The visual cortex receives a stream of high-dimensional sensory input. The role of dense local, recurrent cortical connections in shaping responses to these inputs has been unclear. Here, we show that...

Recurrent cortical networks encode natural sensory statistics via sequence filtering
www.cell.com/neuron/abstr...
#neuroscience

05.03.2026 20:05 β€” πŸ‘ 52    πŸ” 13    πŸ’¬ 1    πŸ“Œ 1
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Linking neural manifolds to circuit structure in recurrent networks Dimensionality reduction methods are widely used in neuroscience to investigate two complementary aspects of neural activity: the distribution of sing…

Excited to share our new paper to be published in Neuron!

With Valentin Schmutz @bio-emergent.bsky.social and Wulfram Gerstner @gerstnerlab.bsky.social, we explore how circuit structure in RNNs shapes network computation and single-neuron responses.
www.sciencedirect.com/science/arti...

06.03.2026 17:11 β€” πŸ‘ 35    πŸ” 10    πŸ’¬ 1    πŸ“Œ 1
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πŸ†οΈ The winners of the #BrainPrize2026 have been announced!

🌟 The @lundbeckfonden.bsky.social @brainprize.org has been awarded to Prof. Patrik Ernfors and Prof. David Ginty for their discoveries on how the nervous system detects and processes touch and pain.

πŸ‘‰ buff.ly/CHkXW5t

#BrainPrize2026

05.03.2026 16:30 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells Lykken, Kanter, Nagelhus, Carpenter, Guardamagna, Moser & Moser (2025) - bioRxiv

Finally getting on top of new papers and god there are so many good ones. This from Lykken, Kanter, @edvardmoser.bsky.social & @m-bmoser.bsky.social is brilliant. Neuropixels showing differential phase shifts across grid modules drive place cell remapping. Elegant grid-to-place transformation story.

02.03.2026 11:27 β€” πŸ‘ 23    πŸ” 8    πŸ’¬ 1    πŸ“Œ 1
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Compact deep neural network models of the visual cortex - Nature Parsimonious deep neural network models can be used for prediction of visual neuron responses.

Nature research paper: Compact deep neural network models of the visual cortex

go.nature.com/3OKRXZU

04.03.2026 09:07 β€” πŸ‘ 23    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Recurrent cortical networks encode natural sensory statistics via sequence filtering The visual cortex receives a stream of high-dimensional sensory input. The role of dense local, recurrent cortical connections in shaping responses to these inputs has been unclear. Here, we show that sequence of inputs interact across time via recurrent interactions, so that natural sequences are boosted compared to irrelevant signals.
03.03.2026 16:23 β€” πŸ‘ 16    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Highly recommended for everyone working with neural data!

03.03.2026 16:58 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
How much neuroscience does a neuroscientist need to know? How much of the brain's learned algorithms depend on the fact it is a brain? We argue: a lot, but surprisingly few details matter. We point to simple biological details -- e.g. nonnegative firing and ...

Insightful angle for mechanistic interpretability!
doi.org/10.48550/arX...

03.03.2026 11:46 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Neurons around a recording ephys electrode

Neurons around a recording ephys electrode

Diagram of monkey looking at a screen in a neuroscience experiment

Diagram of monkey looking at a screen in a neuroscience experiment

Spike rasters for two units in response to a checkerboard shown in the screen. One is an ON neuron, the other is an OFF neuron

Spike rasters for two units in response to a checkerboard shown in the screen. One is an ON neuron, the other is an OFF neuron

Waveforms of single neurons within a single ephys electrode sorted using K-means clustering.

Waveforms of single neurons within a single ephys electrode sorted using K-means clustering.

Just uploaded some of my *hand-crafted* comp-neuro teaching materials, thought they might be useful to someone out there.

It's just some exercise notebooks for data analysis github.com/morales-greg...

02.03.2026 10:02 β€” πŸ‘ 37    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Non‐Canonical Subiculum Circuit Organization and Function The subiculum is highly interconnected with the hippocampus, sub-regions of the thalamus, and the entorhinal and retrosplenial cortices. Together, these regions form a distributed network that plays ...

Great new update on the subiculum circuits!

02.03.2026 14:19 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Legendary!

27.02.2026 20:19 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Mission: record hippocampal place cells in zero gravity
Crew: 3 rats with electrode arrays
Vehicle: Space Shuttle Columbia
Status: data now publicly available on DANDI, 28 years later

The ratstronauts' mission is finally complete. πŸ€πŸš€ h/t NASA

about.dandiarchive.org/blog/2026/02...

27.02.2026 14:54 β€” πŸ‘ 60    πŸ” 23    πŸ’¬ 1    πŸ“Œ 8
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Cognitive Neurophysiology (CNP) - Institute of Basic Medical Sciences We are now hiring two PhDs and a Post Doc:Deadline 1st of March:https://www.jobbnorge.no/en/available-jobs/job/294553/phd-research-fellow-in-machine-learning-for-cognitive-neuroscienceDeadline 4th of ...

We have PhD positions and Post Doc positions available! www.med.uio.no/imb/english/... Please apply if you are interested in human invasive intracranial recordings or applied machine learning in a neuroscientific context.

Deadlines 1st of March (Sunday!) and 4th of March.

Please RT!

27.02.2026 14:40 β€” πŸ‘ 18    πŸ” 10    πŸ’¬ 1    πŸ“Œ 2

I actually couldn't believe it was JUST seven years ago, feels like I've been doing these implants all my life πŸ˜…

26.02.2026 15:02 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Just found this image of a DOWN state in posterior parietal cortex I recorded 7 years ago with my first linear probe, I distinctly remember I couldn't believe my own eyes πŸ˜΅β€πŸ’«

26.02.2026 14:52 β€” πŸ‘ 20    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Vectorized instructive signals in cortical dendrites - Nature Mice learning a neurofeedback brain–computer interface task show neuron-specific teaching signals in cortical dendrites, consistent with a vectorized solution for credit assignment in the brain.

This paper on how the brain may do gradient descent is very cool: www.nature.com/articles/s41...

26.02.2026 03:02 β€” πŸ‘ 146    πŸ” 44    πŸ’¬ 3    πŸ“Œ 2
DANDI Atlas Explorer Demo
YouTube video by DANDI DANDI Atlas Explorer Demo

Where in the brain does DANDI have data? Now you can find out. DANDI Atlas maps datasets onto the Allen CCF mouse brain atlas in interactive 3D. Explore 47 dandisets across 353 brain regions.

atlas.dandiarchive.org

Learn more: about.dandiarchive.org/blog/2026/02...

25.02.2026 19:43 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Neuronal calcium spikes enable vector inversion in the Drosophila brain In the fly central complex, PFNa neurons switch from firing classical sodium spikes when depolarized to firing non-canonical T-type calcium spikes when hyperpolarized. This bidirectional spiking allow...

www.cell.com/cell/fulltex...

We had a lot of fun working on this project (led by Itzel Ishida, not on bluesky). Some interesting highlights from the paper -

06.01.2026 16:35 β€” πŸ‘ 59    πŸ” 28    πŸ’¬ 1    πŸ“Œ 3
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Why You Can’t Remember Being a Toddler This form of amnesia is almost universal, but has long been overlooked.

Why can't you remember being a toddler? Or can you?

Nice feature in Time of our lab's work on infantile amnesia at @tcddublin.bsky.social

Also of the labs of @sarahdpower.bsky.social at MPI Berlin, @franklandlab.bsky.social at Sick Kids, and Nick Turk-Browne at Yale.

time.com/7380496/why-...

25.02.2026 08:31 β€” πŸ‘ 36    πŸ” 17    πŸ’¬ 2    πŸ“Œ 1
Details | Working at Bristol | University of Bristol

🚨JOB alert🚨

We have three (yes, THREE) 🌟lectureships🌟 advertised in the School of Biological Sciences, University of Bristol.

Broad remit, including #AnimalBehaviour & #GlobalChangeBiology

⏱️Deadline: 8th March 2026
πŸ™Please circulate widely

😊Come join us!

Full #job details: tinyurl.com/y3us95rc

23.02.2026 18:13 β€” πŸ‘ 63    πŸ” 97    πŸ’¬ 0    πŸ“Œ 0
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Brain Mapping: Redefining borders in the sensorimotor cortex

πŸ”— buff.ly/UDspPwy

23.02.2026 11:44 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Place cells in CA1 lack topographical organization of firing locations | PNAS Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...

A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. πŸ§ πŸ—ΊοΈ Out now in @pnas.orgΒ www.pnas.org/doi/10.1073/...

19.02.2026 11:53 β€” πŸ‘ 149    πŸ” 43    πŸ’¬ 4    πŸ“Œ 8

New preprint out πŸŽ‰

What happens to the hippocampal β€œplace code” when an animal is actively engaged in a task?

The answer surprised us (and might surprise you too!).

Let's dive in ⬇️

Link:
"Hippocampal trace coding dominates and disrupts place coding" www.biorxiv.org/content/10.6...

19.02.2026 22:25 β€” πŸ‘ 61    πŸ” 22    πŸ’¬ 3    πŸ“Œ 3
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Data-Driven AI for Neuroscience Organizers Carsen Stringer, HHMI/Janelia Research Campus Srini Turaga, HHMI/Janelia Research Campus Atika Syeda, HHMI/Janelia Research Campus Fabian Sinz, University of GΓΆttingen Alice Wang,

πŸ“’ Applications are open! This meeting brings together scientists using data-driven #AI to analyze + model neural circuits and uncover how the brain performs complex computations. 🧠

Apply by May 28 ➑️ janelia.news/NAI26

@computingnature.bsky.social @sinzlab.bsky.social @srinituraga.bsky.social

18.02.2026 16:31 β€” πŸ‘ 10    πŸ” 10    πŸ’¬ 0    πŸ“Œ 1
The Google Summer of Code and Neuroinformatics Unit logos next to each other.

The Google Summer of Code and Neuroinformatics Unit logos next to each other.

Do you want to spend the summer being paid to contribute to open source neuroscience software?

We are taking part in Google Summer of Code again, offering paid, remote placements to work on one of our tools. Open to (nearly) everyone worldwide.

More details: neuroinformatics.dev/get-involved...

20.02.2026 13:45 β€” πŸ‘ 15    πŸ” 9    πŸ’¬ 1    πŸ“Œ 3
Examples of sequences of activity seen in multiple regions of the brain

Examples of sequences of activity seen in multiple regions of the brain

Sequences are everywhere! In every brain region. And are written in stone.

Invariant Activity Sequences Across the Mouse Brain.

Out today, by CΓ©lian Bimbard, with @kenneth-harris.bsky.social.

Based on data by CΓ©lian and by @intlbrainlab.bsky.social.

www.biorxiv.org/content/10.6...

22.12.2025 11:59 β€” πŸ‘ 79    πŸ” 23    πŸ’¬ 3    πŸ“Œ 1
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Do you work or study in the fields of psychology, neuroscience, computer science, artificial intelligence, or philosophy?

What does the term 'representation' mean to you?

We invite you to participate in a brief survey on key conceptual questions across fields.

eu.surveymonkey.com/r/VX9GNXM

12.02.2026 13:39 β€” πŸ‘ 66    πŸ” 60    πŸ’¬ 4    πŸ“Œ 3
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Neuronal spiking in the mammalian forebrain is dominated by a heterogeneous ground state Neuronal firing patterns have significant spatiotemporal variability with no agreed-upon theoretical framework. Using a combined experimental and mode…

With this one in print, I think I finally earned that PhD... πŸ˜…
Presented for the first time at the cosyne when the world ended (March 2020). I'll bring over a summary thread from twitter when it was still twitter...

www.sciencedirect.com/science/arti...

18.02.2026 19:00 β€” πŸ‘ 147    πŸ” 38    πŸ’¬ 10    πŸ“Œ 1

Congrats Dan, so glad to see this out! I remember you presenting this to us virtually during the first lockdown πŸ˜΅β€πŸ’«

18.02.2026 19:14 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Wonderful study, congrats Antoine and the rest of the team! 🀩

18.02.2026 19:07 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0