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Daniel M Spagnolo

@daniel-m-spagnolo.bsky.social

Computational Biologist / Bioinformatician working on novel cancer therapies. Knowledgeable in genomics, multi-omics, bioimaging, and tumour heterogeneity. Pitt-CMU CPCB alumnus. American scientist working (and cycling!) across Cambridge, UK.

165 Followers  |  804 Following  |  6 Posts  |  Joined: 27.01.2025  |  1.8153

Latest posts by daniel-m-spagnolo.bsky.social on Bluesky

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Artios Pharma secures $115M series D to ramp up clinical efforts with DNA damage response pipeline Artios Pharma collected $115 million from an oversubscribed series D that will support its growing ambitions for its pipeline of DNA damage response (DDR)-targeting cancer prospects. | The biotech wil...
17.11.2025 15:21 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Excellent @fogenomics.bsky.social session on AI in drug discovery chaired by @tomdiethe.com w/ an extremely succinct explanation of different generative models & the utility of synthetic data from Helena Andres Terre & a vision for disrupting the drug discovery paradigm/timeline from Sergei Yakneen

30.01.2025 18:23 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics Accurately modeling and predicting RNA biology has been a long-standing challenge, bearing significant clinical ramifications for variant interpretation and the formulation of tailored therapeutics. W...

One of my favorite talks of the day at @fogenomics.bsky.social was Brendan Frey from Deep Genomics discussing the advantages of foundation models with the use case of predicting RNA regulatory mechanisms and designing RNA therapeutics. More details at: www.biorxiv.org/content/10.1...

29.01.2025 20:49 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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ExCeL London / @fogenomics.bsky.social catering to its captive audience of nerds with an X-Wing Starfighter on display #starwars #rebelalliance

29.01.2025 13:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Great talk at Festival of Genomics this morning from @adamrutherford.bsky.social on scientific racism & the eugenic origins of the field of genetics. One takeaway: β€œstandard genetics teaching increases racist essentialist thinking” in students, instead we should start by introducing complex traits.

29.01.2025 12:34 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Excited to attend the Festival of Genomics, which also bookmarks my 1 year milestone at Artios! Looking forward to hearing from the diverse roster of speakers, and making some professional connections.

27.01.2025 13:53 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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