Harald Lund

Postdoctoral Researcher in biology of long nong coding RNAs in macrophages Do you want to contribute to top quality medical The labs of Harald Lund and Alastair Kerr are seeking a postdoctoral fellow for an interdisciplinary project investigating the role of long noncoding R

📣 Postdoc opportunity
We're looking for a postdoc to study lncRNAs in tissue-resident macrophages — an interdisciplinary project between my lab and Alastair Kerr's lab at Karolinska Institutet

Apply here: ki.varbi.com/en/what:job/...
Deadline 8 Feb
#Postdoc #lncRNA #Macrophages #Immunology @ki.se

This paper represents a massive undertaking (6+ years!) led by then PhD student, now Postdoc Keying @keyinglia.bsky.social in collaboration with the Bob Harris lab and many amazing contributors. Thanks to everyone involved!
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Short summary
-Aging causes region-specific myelin degeneration in the spinal cord
-Microglia activate a protective TGFβ1 autocrine loop
-Disrupting microglial Tgfb1/Tgfbr2 leads to myelin loss and behavioral deficits that worsen with age
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TGFβ signaling mediates microglial resilience to spatiotemporally restricted myelin degeneration - Nature Neuroscience Zhu et al. find that aging causes region-specific myelin damage in the spinal cord, which is counteracted by enhanced TGFβ signaling in microglia, revealing a protective mechanism for healthy aging.

Microglia checkpoints promote healthy myelin aging
Our new paper is out in Nature Neuroscience @natneuro.nature.com

www.nature.com/articles/s41...
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Neutrophil-neuronal crosstalk drives arthritis-induced pain Pain in rheumatoid arthritis (RA) often persists despite effective control of inflammation, suggesting distinct mechanisms driving nociception. In both patients and animal models, pain severity does n...

Excited to finally share this story with you! We generated a temporal atlas of the joint-DRG axis during arthritis-induced pain to probe neuroimmune interactions. This revealed OSM and SEMA4D as mediators of neutrophil-neuronal signaling. Many thanks to all coauthors! www.biorxiv.org/content/10.6...

Research Associate - Parsa Group New York, New York, United States

We are looking for a Research Assistant! Come and build a great science team with me! #STEMjobs #ImmunoSky

job-boards.greenhouse.io/chanzuckerbe...